 | Steve Carell als Ben Cooper |
 | Jennifer Garner als Kelly Cooper |
 | Ed Oxenbould als Alexander Cooper |
 | Dylan Minnette als Anthony Cooper |
 | Kerris Dorsey als Emily Cooper |
 | Elise Vargas als Baby Trevor |
| Zoey Vargas als Baby Trevor |
 | Sidney Fullmer als Becky Gibson |
 | Bella Thorne als Celia |
 | Megan Mullally als Nina |
 | Mekai Curtis als Paul Dumphy |
 | Lincoln Melcher als Philip Parker |
 | Reese Hartwig als Elliot Gibson |
 | Martha Hackett als Mrs. Gibson |
 | Mary Mouser als Audrey Gibson |
 | Alex Désert als Mr. Rogue |
 | Toni Trucks als Steph |
 | Liz Carey als Yoga Instructor |
 | Rizwan Manji als Mr. Cellars |
 | Eric Edelstein als Mr. Tonucci |
 | Tara Brook als Receptionist Abby |
| Andrew Franklin als Captain Hook |
 | Cassandra Braden als High School Teacher |
 | Ruben Vernier als Video Game Receptionist |
 | Donald Glover als Greg |
 | Joel Johnstone als Logan |
| Ben Greene als Joaquin |
 | Scott Keiji Takeda als Video Game Exec Yoshi |
 | Burn Gorman als Mr. Brand |
 | Angelyna Martinez-Boyd als Bookstore Employee |
| Dennison Samaroo als Pharmacist |
 | Jesse Garcia als Dwayne |
 | Joey Capone als Jimmy |
 | Jennifer Coolidge als Ms. Suggs |
 | Jonathan Slavin als Tux Shop Employee |
| Jonah Goldman als Actor John Darling |
| Katelyn Hilario als Actor Wendy Darling |
 | Samantha Logan als Heather |
| Alexander Biffin als Thunder from Down Under Dancer |
| Dylan Yeandle als Thunder from Down Under Dancer |
 | David Francis Harris als Thunder from Down Under Dancer |
 | Steve Bannos als Security Guard |
 | Michael Blaiklock als Nagamaki Host |
| Cort Rogers als Stage Hand |
 | Alina Phelan als Pregnant Sheila |
 | Serena Kashmir als Audrey's Friend (uncredited) |
 | Dick Van Dyke als Dick Van Dyke (uncredited) |
| Miguel Arteta | Director |
| Shawn Levy | Producer |
| Rob Lieber | Screenplay |
| Rob Lieber | Screenstory |
| Will Rack | Associate Producer |
| Terry Stacey | Director of Photography |
| Bill Corso | Makeup Artist |
| Philip Steuer | Executive Producer |
| Teressa Hill | Hairstylist |
| Simon Jayes | Camera Operator |
| Christine Lakin | Choreographer |
| John Ross | Sound Re-Recording Mixer |
| Myron Nettinga | Sound Re-Recording Mixer |
| Knox White | Boom Operator |
| Robert Foulkes | Location Manager |
| Roz Music | Makeup Department Head |
| J.D. Schwalm | Special Effects Coordinator |
| Amol Parulekar | Visual Effects Producer |
| Aimee McCue | Set Costumer |
| Geno Hart | Transportation Coordinator |
| Stephen Christensen | Art Direction |
| Andrew DeCristofaro | Supervising Sound Editor |
| Pamela Martin | Editor |
| Nancy Steiner | Costume Design |
| Shandra Page | Hair Department Head |
| Michael Payne | Sound Effects Editor |
| Philip Steuer | Unit Production Manager |
| Garrett Warren | Stunt Coordinator |
| Susan Benjamin | Set Decoration |
| Philip Tallman | Music Editor |
| Christopher Lance | Visual Effects Supervisor |
| Rebecca Robertson | Script Supervisor |
| Patrick McClung | Visual Effects Supervisor |
| Tamara Notcutt | Casting |
| Lynda Kyle Walker | Key Hair Stylist |
| Peter Tothpal | Hairstylist |
| Becky Sullivan | Supervising Sound Editor |
| Everett Chase | Set Designer |
| Ernie Malik | Unit Publicist |
| Dan Muscarella | Color Timer |
| Judith Viorst | Book |
| Michael Corenblith | Production Design |
| Matthew Hirsch | Production Supervisor |
| Linda Matthews | Costume Supervisor |
| Becky Cotton | Makeup Artist |
| Andrea Jackson | Hairstylist |
| Dale Robinette | Still Photographer |
| Terry Scott | Construction Coordinator |
| Dan Hegeman | Sound Effects Editor |
| Susan Hegarty | Dialect Coach |
| Jason Lust | Executive Producer |
| Randi Hiller | Casting |
| Pauletta O. Lewis | Hairstylist |
| Fernand Bos | Music Editor |
| Marty Osborne | Picture Car Coordinator |
| Daniel S. Levine | Producer |
| Lisa Henson | Producer |
| Deborah La Mia Denaver | Makeup Department Head |
| Cinzia Zanetti | Makeup Artist |
| Christophe Beck | Original Music Composer |
| Rachel Bonner | Hairstylist |
| K. Troy Zestos | Hairstylist |
| Louie Esparza | Lead Painter |
| Lisa Nash-Jones | Makeup Artist |
| Susannah Carradine | Art Department Coordinator |
| Sunday Stevens | First Assistant Director |
| Cinzia Zanetti | Key Makeup Artist |
| Tony Castagnola | Greensman |
| John Damiani | Makeup Artist |
| Valerie Jackson | Hairstylist |
| Jenni Clark | Makeup Artist |
| Judy Staats | Makeup Artist |
| Clint Carney | Prop Maker |
| Lorrie Campbell | Set Designer |
| Jeffe Jenkins | Lead Painter |
| Glynna Grimala | Supervising ADR Editor |
| Alan Shultz | Dolly Grip |
| Jimmy Jay | Key Set Costumer |
| Charlie McIntyre | Rigging Gaffer |
| Zoran Veselic | First Assistant Camera |
| Kerry Ann Carmean | Foley Editor |
| Michael Bauman | Chief Lighting Technician |
| John Paul Molloy | Modeling |
| Jose F. Barrios | Rigging Grip |
| Maura Gannett | Studio Teachers |
| Jeremy M. Griffiths | Dolly Grip |
| David Masure-Bosco | Visual Effects Coordinator |
| Richard Crompton | Dolly Grip |
| Rocco Francesco Paolone | Painter |
| Jane Reynolds | Visual Effects Coordinator |
| Nancy MacLeod | Sound Effects Editor |
| Staci Pontius | First Assistant Editor |
| Gary Isbell | Leadman |
| John Stradling | First Assistant Camera |
| Jack Glenn | Dolly Grip |
| Rick Harris | Rigging Grip |
| Robert Heine | First Assistant Camera |
| Les T. Tomita | Key Grip |
| Robert 'Caz' Duffy | First Assistant Camera |
| Bradley Richard | Camera Operator |
| Kim Guthrie | First Assistant Camera |
| J.P. Jones | Property Master |
| Michelle Pazer | Dialogue Editor |
| Aiden Ramos | Sound Recordist |
| Steve Nelson | Sound Mixer |
| Blanca Lista | Production Executive |
