 | Mia Wasikowska als Alice Kingsleigh |
 | Johnny Depp als The Mad Hatter |
 | Anne Hathaway als The White Queen |
 | Helena Bonham Carter als The Red Queen |
 | Crispin Glover als The Knave of Hearts |
 | Matt Lucas als Tweedledee / Tweedledum |
 | Alan Rickman als The Caterpillar (voice) |
 | Stephen Fry als The Cheshire Cat (voice) |
 | Michael Sheen als The White Rabbit (voice) |
 | Timothy Spall als The Bloodhound (voice) |
 | Marton Csokas als Charles Kingsleigh |
 | Lindsay Duncan als Helen Kingsleigh |
 | Geraldine James als Lady Ascot |
 | Tim Pigott-Smith als Lord Ascot |
 | Leo Bill als Hamish Ascot |
 | Frances de la Tour als Aunt Imogene |
 | Christopher Lee als The Jabberwocky (voice) |
 | Paul Whitehouse als The March Hare (voice) |
 | Barbara Windsor als The Dormouse (voice) |
 | Michael Gough als The Dodo (voice) |
 | Imelda Staunton als Tall Flower Faces (voice) |
 | Eleanor Tomlinson als Fiona Chattaway |
 | Rebecca Crookshank als Strange Woman Kisser |
 | Jemma Powell als Margaret Kingsleigh |
 | Eleanor Gecks als Faith Chattaway |
 | Holly Hawkins als Woman with Large Nose in Red Queen Court |
 | Lucy Davenport als Woman with Big Ears in Red Queen Court |
 | Joel Swetow als Man with Large Belly in Red Queen Court |
 | Jessica Oyelowo als Woman with Large Poitrine in Red Queen Court |
 | Ethan Cohn als Man with Large Chin in Red Queen Court |
 | Richard Alonzo als Man with Big Forehead in Red Queen Court |
 | Harry Taylor als Ship Captain |
 | Chris Grabher als Hightopp Hat Juggler |
 | Simone Sault als Party Dancer |
 | Caroline Royce als Party Dancer |
 | Bonnie Parker als Party Dancer |
 | Cortney Palm als Red Queen's Court (uncredited) |
 | Amy Bailey als Hatteress (uncredited) |
| Tim Burton | Director |
| Linda Woolverton | Screenplay |
| Danny Elfman | Original Music Composer |
| Katterli Frauenfelder | Producer |
| Joe Roth | Producer |
| Jennifer Todd | Producer |
| Suzanne Todd | Producer |
| Richard D. Zanuck | Producer |
| Mary Richards | Line Producer |
| Chris Lebenzon | Executive Producer |
| Peter M. Tobyansen | Executive Producer |
| Dariusz Wolski | Director of Photography |
| Chris Lebenzon | Editor |
| Colleen Atwood | Costume Design |
| Michael Leung | Lighting Artist |
| Michael Schlingmann | Storyboard |
| Adam Holmes | Layout |
| Joel Foster | Animation |
| Harald Kraut | Layout |
| Seth Engstrom | Art Direction |
| Lewis Carroll | Novel |
| Ian Blum | Animation |
| Robert Stromberg | Production Design |
| Wayne Dalglish | Stunts |
| Rick Newsome | Storyboard Designer |
| Michael Hansen | Utility Stunts |
| Karen O'Hara | Set Decoration |
| Ken Ralston | Senior Visual Effects Supervisor |
| David Schaub | Animation Supervisor |
| Carey Villegas | Visual Effects Supervisor |
| Sean Phillips | Visual Effects Supervisor |
| Robert Edwards | ADR Mixer |
| Michele Tandy | Finance |
| Katterli Frauenfelder | Co-Producer |
| Tom C. Peitzman | Co-Producer |
| Derek Frey | Associate Producer |
| Lisa Curtis Saunders | Software Engineer |
| Tommy Harper | Unit Production Manager |
| Peter M. Tobyansen | Unit Production Manager |
| Katterli Frauenfelder | First Assistant Director |
| Brandon Lambdin | Second Assistant Director |
| Garrett Warren | Stunt Coordinator |
| Stefan Dechant | Supervising Art Director |
| Kasra Farahani | Assistant Art Director |
| Scott Herbertson | Assistant Art Director |
| Todd Cherniawsky | Art Direction |
| Andrew L. Jones | Art Direction |
| Mike Stassi | Art Direction |
| Christina Ann Wilson | Art Direction |
| Andrea Carter | Art Department Coordinator |
| Elizabeth Keenan | Assistant Set Decoration |
| Mark Weissenfluh | Leadman |
| Christine L. Cantella | Assistant Costume Designer |
| Donna O'Neal | Costume Supervisor |
| Cacey Kirshner | Costumer |
| Terry Baliel | Hair Department Head |
| Leslie Devlin | Key Makeup Artist |
| Patty York | Makeup Artist |
| Joel Harlow | Makeup Artist |
| Richard Alonzo | Special Effects Makeup Artist |
| Debra Coleman | Makeup Artist |
| Tonyia Verna | Makeup Artist |
| Paul Gooch | Key Hair Stylist |
| Karen Asano-Myers | Hairstylist |
| Valli O'Reilly | Makeup Designer |
| Martin Schaer | "A" Camera Operator |
| P. Scott Sakamoto | Steadicam Operator |
| P. Scott Sakamoto | Camera Operator |
| Trevor Loomis | First Assistant Camera |
| James Goldman | Second Assistant Camera |
| Christopher J. Garcia | Second Assistant Camera |
| Luca Kouimelis | Script Supervisor |
| William B. Kaplan | Sound Mixer |
| Thomas Giordano | Boom Operator |
| Peggy Names | Boom Operator |
| Cary Weitz | Boom Operator |
| JC Bond | Additional Editor |
| Christine Kim | First Assistant Editor |
| Michel Aller | First Assistant Editor |
| Jessie Thiele | Post Production Supervisor |
| Michael Semanick | Sound Re-Recording Mixer |
| Tom Johnson | Sound Re-Recording Mixer |
| Steve Boeddeker | Sound Designer |
| Steve Boeddeker | Supervising Sound Editor |
| David Evans | Supervising Sound Editor |
| Paul Apted | Sound Editor |
| Andy Kennedy | Sound Effects Editor |
| Steve Browell | Sound Effects Editor |
| Jack Whittaker | Sound Effects Editor |
| Samir Foco | Sound Effects Editor |
| Geoffrey G. Rubay | Sound Effects Editor |
| Dustin Cawood | Sound Effects Editor |
| Stefan Henrix | Supervising ADR Editor |
| Stefan Henrix | Supervising Dialogue Editor |
| Iain Eyre | Dialogue Editor |
| Michelle Pazer | Dialogue Editor |
| Jason George | Dialogue Editor |
| Phil Freudenfeld | Assistant Sound Editor |
| Dawn Gough | Assistant Sound Editor |
| Tricia Linklater | Assistant Sound Editor |
| Jonathan Null | Foley Supervisor |
| Pascal Garneau | Foley Editor |
| Brian Chumney | Foley Editor |
| Andy Malcolm | Foley Artist |
| Goro Koyama | Foley Artist |
| Barbara Harris | ADR Voice Casting |
| Michael Miller | ADR Mixer |
| David Weisberg | ADR Mixer |
| Howard London | ADR Mixer |
| Sandy Buchanan | ADR Mixer |
| Antony Bayman | ADR Mixer |
| Pip Norton | ADR Mixer |
| Courtney Bishop | ADR Recordist |
| Greg P. Russell | Additional Sound Re-Recording Mixer |
| Bill Banyai | Sound Engineer |
| Louis Elman | ADR Voice Casting |
| Abigail Barbier | ADR Voice Casting |
| Tatjana Bozinovski | Compositor |
| Rafael E. Sánchez | Chief Lighting Technician |
| Patrick Hoeschen | Assistant Chief Lighting Technician |
| J. Michael Popovich | Key Grip |
| Gary Dahlquist | Rigging Gaffer |
| Doug Harlocker | Property Master |
| Josh Roth | Assistant Property Master |
| Karen Jarnecke | Production Coordinator |
| Gregory J. Pawlik Jr. | Second Second Assistant Director |
| C. Scott Baker | Set Designer |
| Jackson Bishop | Set Designer |
| Tammy S. Lee | Set Designer |
| Jeff Markwith | Set Designer |
| Richard F. Mays | Set Designer |
| David Moreau | Set Designer |
| Anne Porter | Set Designer |
| John Villarino | Construction Coordinator |
| Donna Glasser-Hancock | Production Accountant |
| Marybeth Martin-Eck | First Assistant Accountant |
| David Romano | Payroll Accountant |
| Lara Sargent | Post Production Accountant |
| Marnice Wolfe | Post Production Accountant |
| Gabriela Gutentag | Unit Publicist |
| Leah Gallo | Still Photographer |
| Bill Abbott | Music Editor |
| Michael Higham | Music Editor |
| Robert Dawson | Title Designer |
| Lizzie Kelly | Video Assist Operator |
| Brenda Donoho | Set Costumer |
| Craig Barron | Visual Effects Supervisor |
| Robert E. Evans | Visual Effects Producer |
| Ben Grossmann | Visual Effects Supervisor |
| Adam Hart | Stunt Double |
| Eunice Huthart | Stunt Coordinator |
| Ilram Choi | Fight Choreographer |
| Theo Kypri | Stunt Double |
| Jesse V. Johnson | Utility Stunts |
| Tania L. Pearson | Stunts |
| Jasi Cotton Lanier | Stunts |
| Ernie Reyes Jr. | Stunt Double |
| Heather Philips | Stunt Double |
| Frank Torres | Utility Stunts |
| Steve Upton | Utility Stunts |
| Paul Anthony Scott | Stunts |
| Vladimir Kubr | Utility Stunts |
| Alicia Vela-Bailey | Stunts |
| Richard Epper | Utility Stunts |
| Stacey Carino | Stunts |
| Alex Chansky | Stunts |
| Randall Archer | Stunts |
| Scott Armstrong | Utility Stunts |
| Craig Kuehne | Compositor |
| Michael Schlingmann | Storyboard Artist |
