 | Adam Sandler als Dave Buznik |
 | Jack Nicholson als Dr. Buddy Rydell |
 | Marisa Tomei als Linda |
 | Luis Guzmán als Lou |
 | Allen Covert als Andrew |
 | Lynne Thigpen als Judge Daniels |
 | Kurt Fuller als Frank Head |
 | Jonathan Loughran als Nate |
 | Krista Allen als Stacy |
 | January Jones als Gina |
 | Woody Harrelson als Galaxia / Security Guard Gary |
 | John Turturro als Chuck |
 | Kevin Nealon als Sam |
 | Conrad Goode als Bailiff / Lexus Man |
 | Gina Gallego als Bar Waitress |
 | Nancy Carell als Flight Attendant |
 | Marisa Chandler als Flight Attendant |
 | Don Diamont als Man in Seat |
 | Isaac C. Singleton Jr. als Air Marshall |
 | Bobby Knight als Bobby Knight |
 | John McEnroe als John McEnroe |
 | Rudolph Giuliani als Mayor Rudy Giuliani |
| Judith Nathan als Judith Nathan |
| Tony Carbonetti als Tony Carbonetti |
| Bob Sheppard als The Voice of the Yankees |
| Robert Merrill als Robert Merrill |
 | Derek Jeter als Derek Jeter |
 | Lori Heuring als Anger Management Receptionist |
 | Stephen Dunham als Maitre d' |
 | Jeff Morris als Porter |
 | Tony Genaro als Cabbie |
| John Kirk als Bar Waitress's Lawyer |
| Ken Rosier als Buddy's Lawyer |
 | Clint Black als Masseur |
| Rob Steiner als Dave's Co-Worker |
 | Lorna Scott als Lady in Restroom |
 | Bonnie Hellman als Wife at Table |
 | Joe Howard als Husband at Table |
 | Kevin Dunigan als Man #1 in Anger Group |
 | Paul Renteria als Man #2 in Anger Group |
| Kevin Grady als Baseball Fan |
 | Sidney Ganis als Neighbor |
| Larry Morgan als Pool Player |
| Cody Arens als Boy at Yankee Stadium |
 | Michael Arthur als Police Officer |
| Jonathan Osser als Young Dave Buznik |
| Melissa Mitchell als Sara |
| Alan James Morgan als Young Arnie Shankman |
| Lindsey Weber als Arnie's Sister |
| Halley Eveland als Wedgie Boy |
| Taylor Segal als Laughing Girl |
 | Nikki Segal als Girl Playing in Water |
 | John C. Reilly als Older Arnie Shankman (uncredited) |
 | Harry Dean Stanton als Blind Man (uncredited) |
 | Heather Graham als Kendra (uncredited) |
| Kristen Moser als Lauren (uncredited) |
 | Dawn Drake als Girl on Plane (uncredited) |
| Sarah Beth Nelson als Kelly Canfield (uncredited) |
 | Nils Allen Stewart als Tiny (uncredited) |
 | Tom Malloy als Yankees Left Fielder (uncredited) |
| Zack Abramowitz als Baseball Fan (uncredited) |
 | Arnold Chon als Buddhist Monk (uncredited) |
| John Jacobs | Executive Producer |
| Barry Bernardi | Producer |
| Peter Segal | Director |
| Adam Sandler | Executive Producer |
| Teddy Castellucci | Original Music Composer |
| Todd Garner | Executive Producer |
| Allen Covert | Executive Producer |
| Jack Giarraputo | Producer |
| Jeff Gourson | Editor |
| Donald McAlpine | Director of Photography |
| Tim Herlihy | Executive Producer |
| David Dorfman | Writer |
| Allegra Clegg | Co-Producer |
| Derek Dauchy | Co-Producer |
| Michael Ewing | Co-Producer |
| Tom McNulty | Production Executive |
| Roger Mussenden | Casting |
| Alan Au | Production Design |
| Domenic Silvestri | Art Direction |
| Brad Davis | Set Decoration |
| Chris L. Spellman | Set Decoration |
| Ellen Lutter | Costume Design |
| Michael Dilbeck | Music Supervisor |
| Allegra Clegg | Unit Production Manager |
| Cheryl Quarantiello | Unit Production Manager |
| John Hockridge | First Assistant Director |
| Joseph J. Kontra | Second Assistant Director |
| Kiersten Pilar Miller | Second Assistant Director |
| Andy Armstrong | Stunt Coordinator |
| Paul Eliopoulos | Stunt Double |
| Tanner Gill | Stunt Double |
| Patsy Bouge | Post Production Supervisor |
| Timothy S. Wiles | Property Master |
| Nancy Karlin | Script Supervisor |
| Lisa Swain | Production Coordinator |
| Paul Belenardo | Production Accountant |
| Paul C. Babin | Camera Operator |
| Clyde E. Bryan | First Assistant Camera |
| Suzanne Trucks | Second Assistant Camera |
| Michael Scott | "B" Camera Operator |
| A. Anthony Cappello | First Assistant "B" Camera |
| Barnaby Shapiro | Second Assistant "B" Camera |
| Bob Gorelick | Steadicam Operator |
| Abraham Martinez | Camera Loader |
| Alfred Ainsworth | Video Assist Operator |
| Ann Foley | Assistant Costume Designer |
| Elaine Ramires | Costume Supervisor |
| Valerie Zielonka | Key Costumer |
| Jeannie H. Kelly | Costumer |
| Edward T. Hanley | Costumer |
| Leslie Weir | Costumer |
| Javier Arrieta | Costumer |
| Brett Gathrid | Costumer |
| Leslie Brown | Costumer |
| Debbie Travis | Costumer |
| Michael Germain | Makeup Department Head |
| Ann Pala | Makeup Artist |
| Joanne Gair | Makeup Artist |
| Kimberly Greene | Makeup Artist |
| Kimberly Felix | Key Makeup Artist |
| Thomas Real | Hair Department Head |
| Nancy Tong | Key Hair Stylist |
| Joy Zapata | Hairstylist |
| Anne Morgan | Hairstylist |
| Steven R. Mathis | Chief Lighting Technician |
| Keith Baber | Assistant Chief Lighting Technician |
| Michael E. Gips | Electrician |
| Dylan Rush | Electrician |
| Kevin Tiesiera | Electrician |
| Jack Chouchanian | Key Grip |
| Alan K. Schultz | Dolly Grip |
| Jack Glenn | Dolly Grip |
| Ralph Del Castillo | Grip |
| Daisuke Dice Miyake | Grip |
| Tony Sepian | Grip |
| Rick Harris | Key Rigging Grip |
| Dana Baker | Rigging Grip |
| Todd Griffith | Rigging Grip |
| Thomas Causey | Sound Mixer |
| Joseph F. Brennan | Boom Operator |
| Richard Kite | Utility Sound |
| Clay Pinney | Special Effects Supervisor |
| John S. Baker | Special Effects |
| Ralph Coleman | Location Manager |
| Rob Frank | Assistant Location Manager |
| Jane E. Graves | Assistant Location Manager |
| Tom Lackey | Location Scout |
| Heath Banks | Assistant Production Coordinator |
| Jean Nakahara | Assistant Production Coordinator |
| Kerri Smeltzer | Production Secretary |
| Boysie Jereza | Assistant Accountant |
| Edna Wilkerson-Fuentes | Assistant Accountant |
| John Montgomery | Payroll Accountant |
| Karen Higgins | Construction Coordinator |
| Steven Kissick | Construction Foreman |
| Alicia Maccarone | Assistant Art Director |
| Mick Cukurs | Set Designer |
| Patricia Klawonn | Set Designer |
| Jeffrey Beck | Set Designer |
| Karen Teneyck | Graphic Designer |
| Dan Sweetman | Storyboard Artist |
| Alex Hillkurtz | Storyboard Artist |
| Alex Tavoularis | Production Illustrator |
| Al Lewis | Art Department Coordinator |
| Chuck Askerneese | Assistant Property Master |
| Sean Ginevan | Leadman |
| Cameron Matheson | Set Dresser |
| Wendi Laski | Unit Publicist |
| Sidney Ray Baldwin | Still Photographer |
| Timothy Grant Engle | Second Second Assistant Director |
| J.D. Donaruma | Actor's Assistant |
| Jonathan Loughran | Actor's Assistant |
| Kendra Carter | Casting Assistant |
| Ajay Dass | Extras Casting |
| Charlie Scott | Craft Service |
| Edward Flotard | Transportation Coordinator |
| Mike Riportella | Transportation Co-Captain |
| Jason Gourson | First Assistant Editor |
| Tom Costain | First Assistant Editor |
| Laura Weiss | Assistant Editor |
| Elmo Weber | Supervising Sound Editor |
| David Bach | Supervising Sound Editor |
| Derek Vanderhorst | Supervising Sound Effects Editor |
| Orada Jusatayanond | Sound Editor |
| Cameron Steenhagen | Dialogue Editor |
| Robert Jackson | Dialogue Editor |
| Russell Farmarco | Supervising ADR Editor |
| Marc Glassman | Foley Editor |
| Monique Reymond | Foley Artist |
| Jeffrey J. Haboush | Sound Re-Recording Mixer |
| Bill W. Benton | Sound Re-Recording Mixer |
| Tracy Bolt | Sound Recordist |
| Howard London | ADR Recordist |
| J.J. George | Music Editor |
| Stuart Grusin | Music Editor |
| Chris Regan | Color Timer |
| Mary Beth Smith | Negative Cutter |
| Wende Crowley | Music Coordinator |
| Bryan Bonwell | Music Coordinator |
| Sheena Duggal | Visual Effects Supervisor |
| Rob Bredow | CG Supervisor |
| Scott Sohan | Visual Effects Editor |
| Tommy Baratta | Chef |
| J.J. Perry | Stunts |
| Eileen Weisinger | Stunts |
| John Cenatiempo | Stunts |
| Peter Epstein | Stunts |
| John Casino | Stunts |
