 | Cary Grant als Mortimer Brewster |
 | Priscilla Lane als Elaine Harper Brewster |
 | Josephine Hull als Aunt Abby Brewster |
 | Jean Adair als Aunt Martha Brewster |
 | Raymond Massey als Jonathan Brewster |
 | John Alexander als 'Teddy Roosevelt' Brewster |
 | Peter Lorre als Dr. Einstein |
 | Jack Carson als Officer Patrick O'Hara |
 | Edward Everett Horton als Mr. Witherspoon |
 | James Gleason als Lt. Rooney |
 | Grant Mitchell als Reverend Harper |
 | Edward McNamara als Sergeant Brophy |
 | Garry Owen als Taxi Cab Driver |
 | John Ridgely als Officer Saunders |
 | Vaughan Glaser als Judge Cullman |
 | Chester Clute als Dr. Gilchrist |
 | Charles Lane als Reporter at Marriage License Office |
 | Edward McWade als Gibbs |
 | Hank Mann als Photographer at Marriage License Office (uncredited) |
 | Spencer Charters als Marriage License Clerk |
| Sol Gorss als New York Pitcher (uncredited) |
 | Lee Phelps als Umpire (uncredited) |
 | Raymond Walburn als Drummer at baseball game (uncredited) |
 | Spec O'Donnell als Young Man in Line (uncredited) |
 | Leo White als Man in Phone Booth (uncredited) |
| Frank Capra | Director |
| Frank Capra | Producer |
| Jack L. Warner | Producer |
| Joseph Kesselring | Theatre Play |
| Julius J. Epstein | Screenplay |
| Philip G. Epstein | Screenplay |
| Sol Polito | Director of Photography |
| Daniel Mandell | Editor |
| Max Parker | Art Direction |
| Orry-Kelly | Costume Design |
| Perc Westmore | Makeup Artist |
| George Bau | Makeup Artist |
| Eric Stacey | Unit Production Manager |
| Russell Saunders | Assistant Director |
| C.A. Riggs | Sound |
| Robert Burks | Special Effects |
| Byron Haskin | Special Effects |
| Wesley Anderson | Additional Camera |
| Mickey Marigold | Still Photographer |
| Harold Noyes | Grip |
| Hugo Friedhofer | Orchestrator |
| Max Steiner | Original Music Composer |
| Leo F. Forbstein | Original Music Composer |
| Everett Alton Brown | Sound Mixer |
| John Wallace | Makeup Artist |
| Bob Fender | Unit Publicist |
| Anita De Beltrand | Hairstylist |
| Claude Archer | Second Assistant Director |
| Frank Evans | Assistant Camera |
| Charles O'Bannon | Gaffer |
