 | Kristen Wiig als Annie Walker |
 | Maya Rudolph als Lillian Donovan |
 | Rose Byrne als Helen Harris |
 | Chris O'Dowd als Officer Rhodes |
 | Wendi McLendon-Covey als Rita |
 | Ellie Kemper als Becca |
 | Melissa McCarthy als Megan Price |
 | Jon Hamm als Ted |
 | Jill Clayburgh als Judy Walker |
 | Rebel Wilson als Brynn |
 | Matt Lucas als Gil |
 | Michael Hitchcock als Don Cholodecki |
 | Tim Heidecker als Douglas Price |
 | Franklyn Ajaye als Mr. Donovan |
 | Lynne Marie Stewart als Mrs. Donovan |
 | Terry Crews als Rodney |
 | Jessica St. Clair als Whitney |
 | Kali Hawk als Kahlua |
 | Andy Buckley als Helen's Husband |
 | Matt Bennett als Helen's Stepson |
 | Nancy Carell als Helen's Tennis Partner |
 | Melanie Hutsell als Carol |
 | Carnie Wilson als Carnie Wilson |
 | Chynna Phillips als Chynna Phillips |
 | Wendy Wilson als Wendy Wilson |
 | Joe Nuñez als Oscar |
 | Mia Rose Frampton als Jewelry Store Girl |
 | Tom Yi als Jewelry Store Couple |
 | Elaine Kao als Jewelry Store Couple |
 | Mitch Silpa als Flight Attendant Steve |
 | Dana Powell als Flight Attendant Claire |
 | Greg Tuculescu als Kevin |
 | Brian Petsos als Pete |
 | Ben Falcone als Air Marshall Jon |
 | Richard Riehle als Bill Cozbi |
 | Suzanne LaChasse als Hostess (uncredited) |
 | Annie Mumolo als Nervous Woman on Plane |
 | Jillian Bell als Girl at Shower |
 | Ariane Price als Girl at Shower |
 | Paul Feig als Wedding Guest (uncredited) |
| Paul Feig | Director |
| Judd Apatow | Producer |
| Paul Feig | Executive Producer |
| Kristen Wiig | Screenplay |
| Annie Mumolo | Screenplay |
| Barry Mendel | Producer |
| Clayton Townsend | Producer |
| Jonathan Karp | Music Supervisor |
| Michael Andrews | Original Music Composer |
| Robert D. Yeoman | Director of Photography |
| Allison Jones | Casting |
| Michael L. Sale | Editor |
| William Kerr | Editor |
| Jefferson Sage | Production Design |
| Christine Wada | Costume Design |
| Leesa Evans | Costume Design |
| Douglas A. Mowat | Set Decoration |
| Keith P. Cunningham | Art Direction |
| Jose Zamora | Hairstylist |
| Heba Thorisdottir | Makeup Department Head |
| Janine Rath-Thompson | Hair Department Head |
| David Danon | Key Hair Stylist |
| Sheila Waldron | Script Supervisor |
| Suzanne Hanover | Still Photographer |
| Ari Jacobs | Art Department Coordinator |
| George H. Anderson | Supervising Sound Editor |
| Adam Jenkins | Sound Re-Recording Mixer |
| Marc Fishman | Sound Re-Recording Mixer |
| Cindy Marty | Sound Effects Editor |
| Ken McLaughlin | Production Sound Mixer |
| Casey Hotchkiss | Camera Operator |
| Chris Haarhoff | Steadicam Operator |
| Chris Haarhoff | Camera Operator |
| Donald Frazee | Special Effects Coordinator |
| Jessie Graff | Stunts |
| James Matheny | Dialogue Editor |
| Larry Kemp | Dialogue Editor |
| Tammy Fearing | ADR Supervisor |
| Joe Schiff | ADR Editor |
| Greg Zimmerman | ADR Recordist |
| Greg Steele | ADR Mixer |
| Goro Koyama | Foley Artist |
| Andy Malcolm | Foley Artist |
| Stephen Muir | Foley Recordist |
| Jack Heeren | Foley Mixer |
| Don White | Foley Mixer |
| Jenna Dalla Riva | Foley Recordist |
| Lisa Goldberg | Associate Producer |
| Olivia Summers | Stunt Driver |
| Boni Yanagisawa | Stunts |
| Georgina Tsoar | Stunt Driver |
| Olivia Summers | Stunts |
| Heather Martin | Stunts |
| Jessica Harbeck | Stunts |
| Kristen Hance | Stunts |
| Jennifer Adams | Stunts |
| Janene Carleton | Stunts |
| Kristen Wiig | Co-Producer |
| Annie Mumolo | Co-Producer |
| Veronica Lorenz | Makeup Artist |
| Darrin Prescott | Stunts |
