 | Joaquin Phoenix als Kenai (voice) |
 | Jeremy Suarez als Koda (voice) |
 | Jason Raize als Denahi (voice) |
 | Rick Moranis als Rutt (voice) |
 | Dave Thomas als Tuke (voice) |
 | D.B. Sweeney als Sitka (voice) |
 | Joan Copeland als Tanana (voice) |
 | Michael Clarke Duncan als Tug (voice) |
 | Harold Gould als Old Denahi (voice) |
 | Paul Christie als Ram #1 (voice) |
 | Danny Mastrogiorgio als Ram #2 (voice) |
 | Estelle Harris als Old Lady Bear (voice) |
 | Greg Proops als Male Lover Bear (voice) |
 | Pauley Perrette als Female Lover Bear (voice) |
 | Bumper Robinson als Chipmunks (voice) |
 | Darko Cesar als Foreign Croatian Bear (voice) |
| Angayuqaq Oscar Kawagley als Inuit Narrator (voice) |
 | Sherry Lynn als Additional Voice (voice) |
 | Mickie McGowan als Additional Voice (voice) |
 | Debi Derryberry als Additional Voices (voice) |
 | Patrick Pinney als Additional Voices (voice) |
| Aaron Blaise | Director |
| Robert Walker | Director |
| Mark Mancina | Original Music Composer |
| Matthew Jon Beck | Casting |
| Mary Hidalgo | Casting |
| Tim Mertens | Editor |
| Phil Collins | Original Music Composer |
| Tab Murphy | Screenplay |
| Lorne Cameron | Screenplay |
| Chuck Williams | Producer |
| Steve Bencich | Screenplay |
| Ron J. Friedman | Screenplay |
| Phil Collins | Songs |
| Robh Ruppel | Art Direction |
| Jeff Draheim | Associate Editor |
| Matt Whitlock | Animation Manager |
| Bill Perkins | Visual Development |
| Bruce Anderson | Production Manager |
| Hans Bacher | Visual Development |
| Richie Chavez | Visual Development |
| Paul A. Felix | Visual Development |
| Douglas Henderson | Visual Development |
| Xiangyuan Jie | Visual Development |
| Sai Ping Lok | Visual Development |
| Franc Reyes | Visual Development |
| Harald Siepermann | Visual Development |
| Marcelo Vignali | Visual Development |
| Terryl Whitlatch | Visual Development |
| Nathan Greno | Story |
| Byron Howard | Supervising Animator |
| Alex Kupershmidt | Supervising Animator |
| Ruben A. Aquino | Supervising Animator |
| James Young Jackson | Supervising Animator |
| Tony Stanley | Lead Animator |
| Broose Johnson | Lead Animator |
| Anthony Wayne Michaels | Lead Animator |
| Tom Gately | Lead Animator |
| Jonathan Annand | Animation |
| Gregg Azzopardi | Animation |
| Robert Bryan | Animation |
| Don Crum | Animation |
| Steve Mason | Animation |
| Branko Mihanovic | Animation |
| Jean-Claude Tran | Animation |
| John Webber | Animation |
| Ian White | Animation |
| Travis Blaise | Animation |
| Jason Boose | Animation |
| Scott Kersavage | CGI Supervisor |
| Brion McIntosh | First Assistant Editor |
| Bruce Tauscher | Color Timer |
| Christopher W. Gee | Technical Supervisor |
| David Hoselton | Screenplay |
| Igor Khait | Associate Producer |
| Garrett Wren | Visual Effects Supervisor |
| Rune Brandt Bennicke | Character Designer |
| Kevin Deters | Story |
| Thom Enriquez | Story |
| Broose Johnson | Story |
| John Norton | Story |
| Stevie Wermers-Skelton | Story |
| Woody Woodman | Story |
| Kevin Harkey | Story |
| John Puglisi | Story |
| Darko Cesar | Animation |
| Robert O. Corley | Animation |
| Sasha Dorogov | Animation |
| Trey Finney | Animation |
| Sarah Mercey-Boose | Animation |
| Dominic M. Carola | Animation |
| Theodore Anthony Lee Ty | Animation |
| Michael Benet | Animation |
| John E. Hurst | Animation |
| Rune Brandt Bennicke | Lead Animator |
| Stephanie Mendoza | Production Accountant |
| Earl Coffman | Compositors |
| Dave Metzger | Orchestrator |
| Earl Ghaffari | Music Editor |
| Bérénice Robinson | Post-Production Manager |
| Leslie Moes | Post Production Supervisor |
| Richard L. Anderson | Supervising Sound Effects Editor |
| Mike Chock | Supervising Sound Effects Editor |
| Steve Lee | Sound Effects Editor |
| Petra Bach | ADR Supervisor |
| Piero Mura | ADR Editor |
| Reuben Simon | Foley Editor |
| Mark Binder | Sound Design Assistant |
| Chris DeLaGuardia | Color Timer |
| Mary Beth Smith | Negative Cutter |
| Rick Mackay | Negative Cutter |
| Donald Dowd | Special Effects |
| The Blind Boys of Alabama | Songs |
| Tina Turner | Songs |
