 | Nicolas Cage als Seth |
 | Meg Ryan als Maggie Rice |
 | Andre Braugher als Cassiel |
 | Dennis Franz als Nathaniel Messinger |
 | Colm Feore als Jordan |
 | Robin Bartlett als Anne |
 | Joanna Merlin als Teresa Messinger |
 | Sarah Dampf als Susan |
 | Rhonda Dotson als Susan's Mother |
 | Nigel Gibbs als Doctor |
 | John Putch als Man in Car |
 | Lauri Johnson als Woman in Car |
| Christian Aubert als Foreign Visitor in Car |
 | Jay Patterson als Air Traffic Controller |
 | Shishir Kurup als Jimmy, Anesthesiologist |
 | Brian Markinson als Tom, Surgical Fellow |
 | Elisabeth Shue als Pregnant Woman |
 | Alexander Gould als Little Boy (Uncredited) |
| Kiều Chinh als Asian Woman |
 | Nick Offerman als Construction Worker |
| Dana Stevens | Screenplay |
| Brad Silberling | Director |
| Wim Wenders | Screenplay |
| Richard Reitinger | Screenplay |
| Peter Handke | Author |
| Dawn Steel | Producer |
| Lynzee Klingman | Editor |
| John Seale | Director of Photography |
| Charles Roven | Producer |
| Gabriel Yared | Original Music Composer |
| Arnon Milchan | Executive Producer |
| Robert Cavallo | Executive Producer |
| Charles Newirth | Executive Producer |
| Lilly Kilvert | Production Design |
| Douglas Segal | Co-Producer |
| Kelley Smith-Wait | Co-Producer |
| Danny Bramson | Music Supervisor |
| Shay Cunliffe | Costume Design |
| David Rubin | Casting |
| Allegra Clegg | Unit Production Manager |
| Michele Panelli-Venetis | First Assistant Director |
| Matt Rebenkoff | Second Assistant Director |
| Jeff Levine | Associate Producer |
| Alan Glazer | Associate Producer |
| Gretchen Rau | Set Decoration |
| John Warnke | Art Direction |
| Dianne Wager | Assistant Art Director |
| Patrick Cassidy | Leadman |
| Martha Johnston | Set Designer |
| John P. Goldsmith | Set Designer |
| Anthony D. Parrillo | Set Designer |
| Dianne Dreyer | Script Supervisor |
| John Rhode | Camera Operator |
| Calmar Roberts | First Assistant Camera |
| Trevor Loomis | Second Assistant Camera |
| Murray Close | Still Photographer |
| Ian Kelly | Video Assist Operator |
| Morris Flam | Chief Lighting Technician |
| Jeff Pelton | Camera Loader |
| Heather Green | Camera Loader |
| John Carney | Assistant Chief Lighting Technician |
| Dennis J. Lootens | Rigging Gaffer |
| Bobby Huber | Key Grip |
| Scott Hillman | Best Boy Grip |
| Bryan Ashford | Dolly Grip |
| Coleman L. Hart | Key Rigging Grip |
| David Gulick | Property Master |
| Peter C. Clarke | Assistant Property Master |
| Mark Gantt | Assistant Property Master |
| David MacMillan | Sound Mixer |
| Harrison D. Marsh | Boom Operator |
| Perry Dodgson | Cableman |
| Carol Hybi | Costume Supervisor |
| Donna Casey-Aira | Assistant Costume Designer |
| Alan Martin | Costumer |
| Taryn Walsh | Costumer |
| Gail Just | Costumer |
| Hallie D'Amore | Key Makeup Artist |
| Allen Weisinger | Makeup Artist |
| Lutz Wesemann | Makeup Artist |
| Colleen Callaghan | Key Hair Stylist |
| Joseph Coscia | Hairstylist |
| Sally Hershberger | Hairstylist |
| Thomas R. Burman | Makeup Effects Designer |
| Bari Dreiband-Burman | Makeup Effects Designer |
| Anthony Allen Barlow | Makeup Effects Designer |
| Peter Maroti | Makeup Effects Designer |
| Adam Boome | Associate Editor |
| Michael Hofacre | Associate Editor |
| Danya Joseph | Assistant Editor |
| Eric Tignini | Second Second Assistant Director |
| Shelley Kirkwood | Unit Publicist |
| David Blitstein | Special Effects Coordinator |
| Doug Coleman | Stunt Coordinator |
| Daniel W. Barringer | Stunt Coordinator |
| Bobby Joe Garren | Greensman |
| Lauren Ross | Location Manager |
| Ken Haber | Location Manager |
| Steve Dayan | Location Manager |
| Mark B. Johnson | Assistant Location Manager |
| Joel Marrow | Transportation Coordinator |
| Randy Cantor | Transportation Captain |
| Butch West | Construction Coordinator |
| Jess Gonchor | Construction Foreman |
| Thomas E. Brown | Painter |
| Chuck Eskridge | Standby Painter |
| Adria Later | Studio Teacher |
| Judith M. Brown | Studio Teacher |
| Jan Garner | Production Accountant |
| Douglas V.R. Shellow | Production Secretary |
| Ronna Kress | Casting Associate |
| Scott French | Casting Assistant |
| Willie Radcliff | Craft Service |
| Todd Rowland | Actor's Assistant |
| Karen Lin | Actor's Assistant |
| Mark A. Mangini | Supervising Sound Editor |
| John Pospisil | Sound Designer |
| Robert J. Litt | Sound Re-Recording Mixer |
| Michael Herbick | Sound Re-Recording Mixer |
| Elliot Tyson | Sound Re-Recording Mixer |
| Thomas J. O'Connell | ADR Mixer |
| David E. Stone | Sound Effects Editor |
| Geoffrey G. Rubay | Sound Effects Editor |
| Julia Evershade | Dialogue Editor |
| Julia Evershade | ADR Editor |
| Christopher Flick | Foley Editor |
| Ezra Dweck | Foley Editor |
| Robert Randles | Music Editor |
| Katherine Quittner | Music Editor |
| Carlton Kaller | Music Editor |
| Ellen Heuer | Foley Artist |
| Michael J. Broomberg | Foley Artist |
| Marilyn Graf | Foley Mixer |
| Sonny Pettijohn | Assistant Sound Editor |
| Elijah Schkeiban | Assistant Sound Editor |
| Paul Hulme | Scoring Mixer |
| Ben Georgiades | Scoring Mixer |
| Gabriel Yared | Orchestrator |
| John Bell | Orchestrator |
| Harry Rabinowitz | Conductor |
| Mo Henry | Negative Cutter |
| Terry Claborn | Color Timer |
| John Nelson | Visual Effects Supervisor |
| Julia Frey | Visual Effects Producer |
| Robin Griffin | Visual Effects Producer |
| John McLaughlin | CG Supervisor |
| Colin Campbell | Compositing Lead |
| John Alden | Stunts |
| Scott Alan Cook | Stunts |
| Eddie Braun | Stunts |
| Steve Blalock | Stunts |
| James Turner | Stunts |
| Max Daniels | Stunts |
| Eliza Coleman | Stunts |
| Rick Sawaya | Stunts |
| Rick Seaman | Stunts |
| Mark Chadwick | Stunts |
| J. Mark Donaldson | Stunts |
| Bob Elmore | Stunts |
| Joe Bucaro III | Stunts |
| Thomas Rosales Jr. | Stunts |
| Ramiro González | Stunts |
| Jason Rodriguez | Stunts |
| Gilbert Rosales | Stunts |
| Jim Stephan | Stunts |
| Brad Bovee | Stunts |
| Brian J. Williams | Stunts |
| Keith Campbell | Stunts |
| Kerry Rossall | Stunts |
| Vince Deadrick Jr. | Stunts |
| Larry Holt | Stunts |
| Julius LeFlore | Stunts |
| Ray Gabriel | Stunts |
| George Marshall Ruge | Stunts |
| Alex Gaona | Stunts |
| Royce L. Minor | Stunts |
| Rashaé Minor | Stunts |
| Eddie Yansick | Stunts |
| Mickey Giacomazzi | Stunts |
| Kathy Jarvis | Stunts |
| Christina Ritzi | Stunts |
| Tanner Gill | Stunts |
| Ramiro Gonzalez III | Stunts |
| Eric Chambers | Stunts |
