 | Will Ferrell als Brad Whitaker |
 | Mark Wahlberg als Dusty Mayron |
 | Linda Cardellini als Sara |
 | Thomas Haden Church als Leo Holt |
 | Scarlett Estevez als Megan |
 | Owen Vaccaro als Dylan |
 | Bobby Cannavale als Dr. Francisco |
 | Hannibal Buress als Griff |
 | Bill Burr als Jerry (Bully's Dad) |
 | Jamie Denbo als Doris |
 | Mark L. Young als Dental Hygienist |
 | Matthew Paul Martinez als Pete (Recording Engineer) |
 | Dave Davis als Panda Singer #1 |
 | James Harlon Palmer als Panda Singer #2 |
| Riley Ann Corbin als Hello Kitty Girl |
| LaJessie Smith als Jean Jacket |
 | Billy 4 Johnston als Red-Head Kid |
| Olivia Renee Dupepe als 4th Grade Bully Girl |
 | Billy Slaughter als Instigator Dad |
 | LaMonica Garrett als Marco (Lakers Coach) |
 | Nathaniel Woolsey als Beer Vendor |
 | Kobe Bryant als Kobe Bryant |
 | John Cena als Cool Dad |
 | Alessandra Ambrosio als Karen |
 | Didi Costine als Adrianna |
| Hector Presedo als Pepe |
 | Zora Ngwaba als Sunday School Girl |
| Beau Joseph Faucheaux als Sunday School Boy |
 | Paul Scheer als The Whip (Arena Radio DJ) |
| D'Vitrius Shirley-Davie als Skater Kid |
| Joshua Probus als Skater Kid |
 | Kerry Cahill als Angry Cone-Lane Mom |
 | Chris Henchy als Panda DJ / Jason Sinclair |
| Caleb J. Middlebrooks als Panda Call |
 | Cooper Dodson als Hearts of Courage Kid |
| Joel K. Berger als Corey from Red Bull |
 | Grayson Thorne Kilpatrick als Fist Bump Kid at Half Pipe |
| Alex Wayne Boutte als Conference Room Employee |
| JoAnna Wortham als Fertility Clinic Employee |
 | Allen Zwolle als Birthday Guy |
| Abigail C Addison als Daughter at Daddy & Daughter Dance (uncredited) |
| Chris Angerdina als Basketball Fan (uncredited) |
 | Michael D. Anglin als Sheriffs (uncredited) |
 | Sue-Lynn Ansari als Guitar Girl (uncredited) |
| John L. Armijo als Sheriff (uncredited) |
| Saber Bankson als Daughter at Dance (uncredited) |
| Charles Barber als TSA Employee (uncredited) |
| Nazeema Bartek als Office Employee / Airport Passenger / Basketball Game (uncredited) |
| Tony Beard als Sportscaster (uncredited) |
| Lukas Bennett als Basketball Player (uncredited) |
| Eric Berris als Panda Radio Station Tech (uncredited) |
 | Tracy Brotherton als Airline Employee (uncredited) |
| Brady Calhoun als Police Officer / Father at Dance (uncredited) |
| Adam McKay | Screenplay |
| Sean Anders | Director |
| Brian Burns | Screenplay |
| Chris Henchy | Screenplay |
| Eric Kissack | Editor |
| Clayton Hartley | Production Design |
| Julio Macat | Director of Photography |
| Will Ferrell | Producer |
| Carol Ramsey | Costume Design |
| Riza Aziz | Executive Producer |
| Adam McKay | Producer |
| Sean Anders | Executive Producer |
| Michael Andrews | Original Music Composer |
| Brad Wilhite | Editor |
| Chris Henchy | Producer |
| John Morris | Producer |
| Jan Pascale | Set Decoration |
| Kevin J. Messick | Executive Producer |
| Brian Burns | Story |
| David Koplan | Executive Producer |
| Diana Pokorny | Executive Producer |
| Elliott Glick | Supervising Art Director |
| Jessica Elbaum | Executive Producer |
| Joey McFarland | Executive Producer |
| Anthony 'Ace' Thomas | Choreographer |
| Anthony 'Ace' Thomas | Stunts |
| Ian Belgard | Acting Double |
| Allison Jones | Casting |
| Dave Jordan | Music Supervisor |
| Jojo Villanueva | Music Supervisor |
| Diana Pokorny | Unit Production Manager |
| Daniel Silverberg | First Assistant Director |
| James Roque Jr. | Second Assistant Director |
| Todd Bryant | Stunt Coordinator |
| Michelle Morrissey | Production Supervisor |
| Cate Hardman | Script Supervisor |
| David Wyman | Sound Mixer |
| Betsy Lindell | Boom Operator |
| Dan Furst | Video Assist Operator |
| Christopher TJ McGuire | Steadicam Operator |
| Christopher TJ McGuire | "A" Camera Operator |
| Michael Applebaum | "B" Camera Operator |
| Greg Finkel | First Assistant Camera |
| Bob E. Krattiger | Chief Lighting Technician |
| Joseph Krattiger | Assistant Chief Lighting Technician |
| Jeremy Hays | Special Effects Coordinator |
| Michael Sabo | Property Master |
| Twig Leveque | Assistant Property Master |
| Jed Pendergrass | Assistant Property Master |
| Joel Prihoda | Leadman |
| Emma Verdugo | Set Decorating Coordinator |
| Senna Shanti | Assistant Costume Designer |
| Richard Schoen | Costume Supervisor |
| Valerie T. O'Brien | Key Costumer |
| Giselle Spence | Seamstress |
| Steve Artmont | Makeup Department Head |
| Nicole Artmont | Key Makeup Artist |
| Howard Berger | Makeup Artist |
| Bridget Cook | Hair Department Head |
| Jennifer Hodges | Key Hair Stylist |
| Johnny Villanueva | Hairstylist |
| Kerri Smeltzer | Production Coordinator |
| Trang Dang | Assistant Production Coordinator |
| K. Emily Levine | Art Department Coordinator |
| Harrison Hartley | Graphic Designer |
| Ryan Falkner | Storyboard Artist |
| Ben Harris | Casting Associate |
| Diane Slattery | Unit Publicist |
| Patti Perret | Still Photographer |
| Timber Kislan | Production Accountant |
| Maureen O'Reilly | Payroll Accountant |
| Paul Linden | Visual Effects Supervisor |
| Jay Vinitsky | Post Production Supervisor |
| Thomas R. Bryant | Visual Effects Editor |
| Andrew DeCristofaro | Supervising Sound Editor |
| Darren Sunny Warkentin | Supervising Sound Editor |
| Terry Porter | Sound Re-Recording Mixer |
| Anna Behlmer | Sound Re-Recording Mixer |
| Dan Hegeman | Sound Effects Editor |
| David Stanke | First Assistant Sound Editor |
| Michael Payne | Supervising Sound Effects Editor |
| John C. Stuver | Dialogue Editor |
| G.W. Brown | Dialogue Editor |
| Kelly Oxford | Foley Supervisor |
| Dan O'Connell | Foley Artist |
| John T. Cucci | Foley Artist |
| James Ashwill | Foley Mixer |
| John Guentner | Foley Mixer |
| Doc Kane | ADR Mixer |
| Thomas J. O'Connell | ADR Mixer |
| Ryan Young | ADR Recordist |
| Jeanette Browning | ADR Recordist |
| Barbara Harris | ADR Voice Casting |
| Terry Wilson | Supervising Music Editor |
| Ryan Castle | Music Editor |
| Randall S. Coe | Construction Coordinator |
| James E. Tocci | Set Designer |
| Walter Schneider | Set Designer |
| Paul Sonski | Set Designer |
| Denny Caira | Transportation Coordinator |
| Lawrence Johnson | Transportation Captain |
| Wallace Frick | Transportation Co-Captain |
| James Wright | Dolby Consultant |
| Aaron Becker | Title Designer |
| Vanessa Galvez | Digital Intermediate Producer |
| Curtis Lindersmith | Digital Intermediate Editor |
| Mike Wilson | Stunt Double |
| Taryn Terrell | Stunts |
| Mark De Alessandro | Stunts |
| Gregory J. Barnett | Stunts |
| Allan Graf | Stunt Driver |
| Danny Epper | Stunts |
