 | Nicolas Cage als Grug Crood (voice) |
 | Emma Stone als Eep Crood (voice) |
 | Ryan Reynolds als Guy (voice) |
 | Catherine Keener als Ugga Crood (voice) |
 | Cloris Leachman als Gran Crood (voice) |
 | Clark Duke als Thunk Crood (voice) |
 | Leslie Mann als Hope Betterman (voice) |
 | Peter Dinklage als Phil Betterman (voice) |
 | Kelly Marie Tran als Dawn Betterman (voice) |
 | Kailey Crawford als Sandy (voice) |
 | Chris Sanders als Belt (voice) |
 | James Ryan als Sash (voice) |
 | Melissa Disney als Guy's Mother (voice) |
 | Joel Crawford als Guy's Father (voice) |
 | Januel Mercado als Shaman Monkey (voice) |
 | Ryan Naylor als Creepo Monkey (voice) |
 | Artemis Pebdani als Additional Voices (voice) |
| Joel Crawford | Director |
| Dan Hageman | Screenplay |
| Kevin Hageman | Screenplay |
| Mark Swift | Producer |
| Chris Sanders | Characters |
| Kirk DeMicco | Characters |
| Paul Fisher | Screenplay |
| Bob Logan | Screenplay |
| Lisa Curtis Saunders | Pipeline Technical Director |
| Kirk DeMicco | Story |
| Chris Sanders | Story |
| Mark Mothersbaugh | Original Music Composer |
| John Cleese | Characters |
| Randy Thom | Sound Designer |
| Brian Chumney | Supervising Sound Editor |
| Leff Lefferts | Supervising Sound Editor |
| Chris Scarabosio | Sound Re-Recording Mixer |
| Leff Lefferts | Sound Re-Recording Mixer |
| Natalia Cronembold | Associate Editor |
| Peter Zaslav | Art Direction |
| Rachel Zusser | Associate Producer |
| James Ryan | Editor |
| Nate Wragg | Production Design |
| Betsy Nofsinger | Visual Effects Supervisor |
| Jakob Hjort Jensen | Head of Animation |
| Januel Mercado | Head of Story |
| Jon Gutman | Head of Layout |
| Wil Whaley | Digital Supervisor |
| Hans Dastrup | Animation Supervisor |
| Antony Gray | Animation Supervisor |
| Fabio Lignini | Animation Supervisor |
| Rani Naamani | Animation Supervisor |
| Liron Topaz | Animation Supervisor |
| Shaun Collaco | Lighting Supervisor |
| Avedis Ekmekjian | Lighting Supervisor |
| C. Jin Im | Lighting Supervisor |
| Sondra Verlander | Lighting Supervisor |
| Mark Sandell | Effects Supervisor |
| Amaury Aubel | Effects Supervisor |
| Domin Lee | Effects Supervisor |
| Richard Shiba | Layout Supervisor |
| Christi Soper Hilt | Casting |
| Evon Freeman | Storyboard Artist |
| Simon Wells | Storyboard Artist |
| Michael Lester | Storyboard Artist |
| Heidi Jo Gilbert | Storyboard Artist |
| Taylor Meacham | Storyboard Artist |
| David Wolter | Storyboard Artist |
| Colin Jack | Storyboard Artist |
| Toniko Pantoja | Storyboard Artist |
| Anthony Zierhut | Storyboard Artist |
| Adam Rosette | Storyboard Artist |
| Tom Caulfield | Storyboard Artist |
| Kaan Kalyon | Storyboard Artist |
| Faryn Pearl | Storyboard Artist |
| Gary Graham | Storyboard Artist |
| Steven A. MacLeod | Storyboard Artist |
| William Salazar | Storyboard Artist |
| Maggie Kang | Storyboard Artist |
| Kerry McAllister | Storyboard Artist |
| Jacquelyn Karambelas | Associate Editor |
| Natalia Cronembold | First Assistant Editor |
| Katie Parody | Assistant Editor |
| Mary Blee | Associate Editor |
| Collin Erker | Assistant Editor |
| Ryan Naylor | Production Coordinator |
| Sébastian Piquet | Character Designer |
| Joe Pitt | Character Designer |
| Philippe Brochu | Visual Development |
| Luca Pisanu | Visual Development |
| Paul Schoeni | Visual Development |
| Leighton Hickman | Visual Development |
| Sébastian Piquet | Visual Development |
| Frederic William Stewart | Visual Development |
| Kirsten Kawamura | Visual Development |
| Ritchie Sacilioc | Visual Development |
| Jesse Aclin | Visual Development |
| Christophe Lautrette | Visual Development |
| Priscilla Wong | Visual Development |
| Ruben Perez | Visual Development |
| Drew Adams | Animation |
| Patrick Danaher | Animation |
| Garrett O'Neal | Animation |
| Luiza Alaniz | Animation |
| Patrick Giusiano | Animation |
| David Polk | Animation |
| Kimberlee Allyn | Animation |
| Thomas Grummt | Animation |
| Robyne Powell | Animation |
| Kristof Serrand | Animation |
| Laura H. Han | Animation |
| David Badgerow | Animation |
| Brooke Shay Bradford | Animation |
| Andrew Harkins | Animation |
| Kevan Shorey | Animation |
| Dane Stogner | Animation |
| John Hill | Animation |
| Laurent Caneiro | Animation |
| Joseph Chong | Animation |
| Martin P. Hopkins | Animation |
| Greg Whittaker | Animation |
| Kelly Vawter | Animation |
| Steven Hornby | Animation |
| Elisabeth Franklin | Animation |
| David Couchariere | Animation |
| Brendan Kirschbaum | Animation |
| Ryan Vicik | Animation |
| Sean Mack | Animation |
| Michelle Cowart | Animation |
| Ludovic Bouancheau | Animation |
| David Weatherly | Animation |
| Alberto Corral | Animation |
| Beril Pisgin-Saglam | Animation |
| Gregory Creaser | Colorist |
| Paul McGhee | Colorist |
| Pascal Garneau | Sound Effects Editor |
| Mac Smith | Sound Effects Editor |
| Jonathan Greber | Dialogue Editor |
| Doug Winningham | Foley Editor |
| Dee Selby | Foley Editor |
| John Roesch | Foley Artist |
| Shelley Roden | Foley Artist |
| Ronni Brown | Foley Artist |
| Jana Vance | Foley Artist |
| Scott Curtis | Foley Mixer |
| Richard Duarte | Foley Mixer |
| Derek McGinley | Sound Re-Recording Assistant |
| Rick Hromadka | Sound Designer |
| Ken Gombos | Mixing Engineer |
| Wataru Hokoyama | Additional Music |
| Pete Siebert | Additional Music |
| Dominick Certo | Music Editor |
| Alfonso Casado Trigo | Conductor |
| Tim Davies | Orchestrator |
| Brian Byrne | Orchestrator |
| Lorenzo Carrano | Orchestrator |
| Ryan Humphrey | Orchestrator |
| Jeremy Levy | Orchestrator |
| Jordan Seigel | Orchestrator |
| James McWilliam | Orchestrator |
| John Cleese | Thanks |
| Jennifer Howell | Thanks |
| Jerry Schmitz | Thanks |
| Tom McGrath | Thanks |
| Christopher DeFaria | Thanks |
| Jack Black | Songs |
