 | Manu Bennett als Frankenstein |
 | Malcolm McDowell als Chairman |
 | Marci Miller als Annie Sullivan |
 | Burt Grinstead als Jed Perfectus |
 | Folake Olowofoyeku als Minerva Jefferson |
 | Anessa Ramsey als Tammy |
 | Yancy Butler als Alexis Hamilton |
 | Charlie Farrell als JB |
 | Shanna Olson als Grace Tickle |
| Leslie Shaw als Eve |
| Helen Loris als Dr. Creamer |
| Pierre Paolo Goya Kobashigawa als Chi Wapp |
| Sebastian Llosa als Steve |
| Emilio Montero als Pablo Zapata |
| G.J. Echternkamp | Director |
| G.J. Echternkamp | Writer |
| Matt Yamashita | Writer |
| Julie Corman | Executive Producer |
| Roger Corman | Producer |
| Jan Glaser | Casting |
| Caitlin McGreal | Casting Associate |
| Sean Fernald | Music Supervisor |
| Lisa Gooding | Production Director |
| Michael Moriatis | Still Photographer |
| G.J. Echternkamp | Editor |
| Maria Elizabeth Bravo Cornejo | Hairstylist |
| Miguel Yamaha Tucno | Hairstylist |
| Romeo Buddy Mayzee | Sound Effects Editor |
| Ryan Villarreal | Sound Effects Editor |
| Erick Jolley | Sound Re-Recording Mixer |
| Edy Enriquez | Visual Effects Producer |
| Anthony J. Rickert-Epstein | Visual Effects Supervisor |
| Luis Llosa | Associate Producer |
| Cindy Brown | Music |
| Gunter Brown | Music |
| John Alexander Rushie | Music |
| Dylan Baker | Editor |
| Steve Ansell | Editor |
| Fernando Gagliuffe | Art Direction |
| Dylan Baker | Set Decoration |
| Juan Durán | Director of Photography |
| Peter Lara Patiño | First Assistant Director |
| Ivailo Tzvetkov | First Assistant Camera |
| Jacob Hayman | Casting Assistant |
| Diego Alex Borghello | Colorist |
| Eric M. Klein | Digital Intermediate Producer |
| Matthew J. McLaren | Online Editor |
| Analía Laos | Script Supervisor |
| Toby Craig | ADR Recordist |
| Martin Quiñones | ADR Recordist |
| Martin Quiñones | ADR Supervisor |
| Iris Posada | ADR Supervisor |
| Mirella Bellido | Boom Operator |
| Tim Chilton | Foley Artist |
| Steve Walter | Foley Artist |
| Ashu Boni | Foley Recordist |
| Martin Quiñones | Foley Recordist |
| Iris Posada | Foley Supervisor |
| Ashu Boni | Sound Editor |
| Erick Jolley | Sound Designer |
| Gregor Mazurczuk | Sound Recordist |
| Alex Fichera | Main Title Designer |
| James Payfer | Rotoscoping Artist |
| Harry Walton | Rotoscoping Artist |
| Dominic Bonavitacola | VFX Artist |
| Logan Sprangers | VFX Artist |
