 | Samantha Morton als Annie Parker |
 | Helen Hunt als Mary-Claire King |
 | Aaron Paul als Paul |
 | Alice Eve als Louise |
 | Maggie Grace als Sarah |
 | Rashida Jones als Kim |
 | Corey Stoll als Sean |
 | Richard Schiff als Mr. Allen |
 | Bradley Whitford als Marshall |
 | Marley Shelton als Joan |
 | Ben McKenzie als Tom |
 | James Tupper als Steve |
 | Robert Pine als Dr. Frank |
 | Bob Gunton als Dr. Benton |
 | Chris Mulkey als Ralph Parker |
 | Chad Lindberg als Funeral Home Employee |
 | Benjamin Stockham als Young William (Age 8) |
 | Ryan Wynott als Young William (Age 12) |
 | Jade Duncan als Young Annie Parker |
 | Olivia Rose Keegan als Young Joan Parker |
| Stuart W. Ross | Producer |
| Adam Bernstein | Screenplay |
| Steven Bernstein | Screenplay |
| Steven Bernstein | Director |
| Douglas Crise | Editor |
| Steven Bernstein | Producer |
| C. Steve Goldstein | Associate Producer |
| Steven Bramson | Original Music Composer |
| Michael Moss | Associate Producer |
| Mick Partridge | Co-Producer |
| Johnathan Brownlee | Executive Producer |
| Venus Kanani | Casting |
| Darlene Winter | Executive Producer |
| Oliver Wheeler | Associate Producer |
| Jaki West | Co-Producer |
| Ted Hayash | Director of Photography |
| Ron Senkowski | Producer |
| Nolan Mcdonald | Executive Producer |
| Tara Finegan | Executive Producer |
| Keith Kjarval | Producer |
| Randolf Turrow | Line Producer |
| Aaron L. Gilbert | Executive Producer |
| Clark Peterson | Producer |
| Brigitte Huff | Co-Producer |
| Rob Howeth | Production Design |
| Mary Vernieu | Producer |
| Sidney Powell | Executive Producer |
| Aiyana Trotter | Art Department Coordinator |
| Chikako Suzuki | Art Direction |
| Dan Kneece | Camera Operator |
| Dorit Hurst | Set Decoration |
| Michael Ferris | Camera Operator |
| Anne Melville | Script Supervisor |
| Mary Vernieu | Casting |
