 | Katie Holmes als Kim |
 | Guy Pearce als Alex Hirst |
 | Bailee Madison als Sally Hirst |
 | Jack Thompson als Harris |
 | Alan Dale als Jacoby |
 | Emelia Burns als Caterer |
 | Nicholas Bell als Psychiatrist |
 | James Mackay als Librarian |
 | Eddie Ritchard als Housekeeper |
 | Bruce Gleeson als Buggy Driver |
| Gary McDonald als Blackwood |
 | Carolyn Shakespeare-Allen als Airport Cart Driver |
 | Julia Blake als Mrs. Underhill |
 | Trudy Hellier als Evelyn Jacoby |
| Terry Kenwrick als Bill |
 | Grant Piro als Creature (voice) |
 | Todd MacDonald als Creature (voice) |
| Dylan Young als Creature (voice) |
 | Guillermo del Toro als Creature (Voice) |
 | Libby Gott als Nurse |
| Angus Smallwood als Creature (voice) |
| David Tocci als Workman |
| Lance Drisdale als Policeman |
| Abbe Holmes als Joanne (voice) |
| Tom Williams | Executive Producer |
| Mary Vernieu | Casting |
| Christine King | Casting |
| Stephen Jones | Executive Producer |
| Roger Ford | Production Design |
| William Horberg | Executive Producer |
| Marco Beltrami | Original Music Composer |
| Jill Bilcock | Editor |
| Troy Nixey | Director |
| Venus Kanani | Casting |
| Oliver Stapleton | Director of Photography |
| Buck Sanders | Original Music Composer |
| Nick Nunziata | Producer |
| Guillermo del Toro | Screenplay |
| Matthew Robbins | Screenplay |
| Guillermo del Toro | Producer |
| Nigel McKeand | Teleplay |
| Mark Johnson | Producer |
| Simon Harkom | Greensman |
| Robert Mackenzie | Sound Designer |
| Calum McFarlane | Camera Operator |
| Louis Puli | Additional Camera |
| Scott Shapiro | Visual Effects Producer |
| Steven Sallybanks | Scenic Artist |
| Ross Melling | Sculptor |
| Amelia Ford | Visual Effects Editor |
| Kristin Witcombe | Script Supervisor |
| Christopher Hand | Greensman |
| Carolyn Wells | Set Costumer |
| Anna Vincent | Unit Publicist |
| Erica Wells | Hairstylist |
| Ian Richter | Scenic Artist |
| Mélanie Poudroux | Sculptor |
| Weining Lin | Sculptor |
| Ineke Majoor | Visual Effects Producer |
| Ross Emery | Second Unit Cinematographer |
| Marko Anttonen | Set Designer |
| Andrew Neil | Sound Effects Editor |
| Kerrie Brown | Set Decoration |
| Wendy Chuck | Costume Design |
| Darrin Keough | Camera Operator |
| Carolyn Johns | Still Photographer |
| Craig Beckett | Music Editor |
| Chris Anderson | Stunt Coordinator |
| Lisa Inman | Script Supervisor |
| Laura Erikson | Studio Teachers |
| Lucinda Thomson | Art Direction |
| Shanthi Nadaraja | Art Department Coordinator |
| Max Haymes | Construction Coordinator |
| Nicholas Dare | Set Designer |
| Erin McGookin | Digital Intermediate |
| Ben Lowe | Location Manager |
| Elaine Kusmishko | Assistant Art Director |
| Adam Connelly | Foley |
| Mario Vaccaro | Foley |
| Bruce Emery | Dolby Consultant |
| David Hollingsworth | Digital Intermediate |
| Chiara Tripodi | Makeup Artist |
| Michael Bell | Assistant Art Director |
| Kerry Thompson | Costume Supervisor |
| Jason Ruder | Music Editor |
| Gary Tippett | Sculptor |
| Katherine Brown | Makeup Effects |
| Peter McCaffrey | Steadicam Operator |
| Billy Browne | First Assistant Editor |
| Glenn Newnham | Supervising Sound Editor |
| Nicholas Tripodi | Animation |
| Shane Hall | Animation |
| Daniel Fotheringham | Animation |
| Mark Hanneysee | Best Boy Grip |
