 | Peter Sellers als Group Capt. Lionel Mandrake / President Merkin Muffley / Dr. Strangelove |
 | George C. Scott als General "Buck" Turgidson |
 | Sterling Hayden als Brigadier General Jack D. Ripper |
 | Keenan Wynn als Colonel Bat Guano |
 | Slim Pickens als Major "King" Kong |
 | Peter Bull als Botschafter De Sadesky |
 | James Earl Jones als Lt. Lothar Zogg |
 | Tracy Reed als Miss Scott |
 | Jack Creley als Mr. Staines |
 | Frank Berry als Lt. Dietrich |
 | Robert O'Neil als Adm. Randolph |
 | Glenn Beck als Lt. Kivel |
| Roy Stephens als Frank |
 | Shane Rimmer als Capt. 'Ace' Owens |
 | Hal Galili als Burpelson AFB Defense Team Member |
| Paul Tamarin als Lt. Goldberg |
 | Laurence Herder als Burpelson AFB Defense Team Member |
| John McCarthy als Burpelson AFB Defense Team Member |
 | Gordon Tanner als Gen. Faceman |
 | Burnell Tucker als Mandrake' aide (uncredited) |
 | Victor Harrington als War Room Aide (uncredited) |
| Laurie Johnson | Original Music Composer |
| Terry Southern | Screenplay |
| Ken Adam | Production Design |
| Victor Lyndon | Producer |
| Stanley Kubrick | Producer |
| Stanley Kubrick | Screenplay |
| Peter George | Screenplay |
| Gilbert Taylor | Director of Photography |
| Peter George | Novel |
| Leon Minoff | Executive Producer |
| Stanley Kubrick | Director |
| Anthony Harvey | Editor |
| Wally Veevers | Special Effects |
| Bob Penn | Still Photographer |
| Alan Bryce | Special Effects |
| John Aldred | ADR & Dubbing |
| John Cox | Sound |
| Garth Inns | Special Effects |
| Ray Lovejoy | Assistant Editor |
| Clifton Brandon | Production Manager |
| Kelvin Pike | Camera Operator |
| Eric Rattray | Assistant Director |
| Peter Murton | Art Direction |
| Stuart Freeborn | Makeup Artist |
| Barbara Ritchie | Hairstylist |
| Arthur 'Weegee' Fellig | Special Effects |
| Leslie Hodgson | Sound Editor |
| Michael Walter | Key Grip |
| Jim Body | Visual Effects Camera |
| Pamela Carlton | Continuity |
| Alan Stuart | Stunt Double |
| Richard Bird | Sound Recordist |
| Pablo Ferro | Title Designer |
