 | Michael Caine als Doctor Robert Elliott |
 | Nancy Allen als Liz Blake |
 | Angie Dickinson als Kate Miller |
 | Keith Gordon als Peter Miller |
 | Dennis Franz als Detective Marino |
 | David Margulies als Dr. Levy |
 | Ken Baker als Warren Lockman |
 | Susanna Clemm als Betty Luce |
 | Brandon Maggart als Cleveland Sam |
 | Amalie Collier als Cleaning Woman |
 | Mary Davenport als Woman in Restaurant |
 | Anneka Di Lorenzo als Nurse |
| Norman Evans als Ted |
| Robbie L. McDermott als Man in Shower |
| Bill Randolph als Chase Cabbie |
| Sean O'Rinn als Museum Cabbie |
| Fred Weber als Mike Miller |
 | Samm-Art Williams als Subway Cop |
| Robert Lee Rush als Hood #1 |
| Anthony Boyd Scriven als Hood #2 |
| Robert McDuffie als Hood #3 |
| Frederick Sanders als Hood #4 |
| Paul DeCeglie als TV Reporter (uncredited) |
 | William Finley als Bobbi (voice) (uncredited) |
| Erika Katz als Girl in Elevator (uncredited) |
 | Mark Margolis als Patient at Bellvue Hospital (uncredited) |
| Lisa Peluso als Museum Girl (uncredited) |
| Jerry Schram als Building Tenant (uncredited) |
 | Victoria Lynn Johnson als Angie Dickinson‘s Nude Body Double |
| Samuel Z. Arkoff | Executive Producer |
| Gerald B. Greenberg | Editor |
| Brian De Palma | Director |
| Pino Donaggio | Original Music Composer |
| George Litto | Producer |
| Ralf D. Bode | Director of Photography |
| Brian De Palma | Writer |
| Natale Massara | Music Director |
| Gary J. Brink | Set Decoration |
| Michael Rauch | Assistant Director |
| Vic Ramos | Casting |
| Gary Weist | Art Direction |
| Fred C. Caruso | Associate Producer |
| Joe Cranzano | Makeup Artist |
| Bob Grimaldi | Hairstylist |
| Gary Jones | Costume Design |
| Tony Lloyd | Makeup Artist |
| Ann Roth | Costume Design |
| Fred C. Caruso | Production Manager |
| BJ Davis | Stunts |
| BJ Davis | Stunt Double |
| William Eustace | Second Assistant Director |
| Paula Mazur | Assistant Director Trainee |
| Robert Rothbard | Second Second Assistant Director |
| Gilbert Gertsen | Carpenter |
| Billy Kane | Property Master |
| William Lowry | Construction Coordinator |
| Ernest W. Southern | Scenic Artist |
| Paul J. Wilson | Props |
| Ed Abele | Boom Operator |
| John H. Bolz | Sound Mixer |
| Peter Ilardi | Sound Recordist |
| Lowell Mate | Assistant Sound Editor |
| Michael Moyse | Sound Editor |
| Dan Sable | Supervising Sound Editor |
| Dick Vorisek | Sound Re-Recording Mixer |
| Jean Fraser Wardle | Assistant Sound Editor |
| Randall Coleman | Apprentice Sound Editor |
| Victor Magnotta | Stunt Coordinator |
| Tim Gallin | Stunts |
| Steve James | Stunts |
| Holly Bower | Still Photographer |
| Marc Hirschfeld | Assistant Camera |
| Jack Kennedy | Dolly Grip |
| Ed Quinn | Key Grip |
| Michael Stone | Camera Operator |
| David Wagreich | Second Assistant Camera |
| James C. Walsh | Best Boy Grip |
| William Ward | Gaffer |
| Craig DiBona | Camera Operator |
| Adam Kimmel | Other |
