 | Eddie Redmayne als Newt Scamander |
 | Jude Law als Albus Dumbledore |
 | Mads Mikkelsen als Gellert Grindelwald |
 | Ezra Miller als Credence Barebone / Aurelius Dumbledore |
 | Dan Fogler als Jacob Kowalski |
 | Alison Sudol als Queenie Goldstein |
 | Callum Turner als Theseus Scamander |
 | Jessica Williams als Eulalie 'Lally' Hicks |
 | Katherine Waterston als Porpentina 'Tina' Goldstein |
 | Oliver Masucci als Anton Vogel |
 | Richard Coyle als Aberforth Dumbledore |
 | William Nadylam als Yusuf Kama |
 | Maria Fernanda Cândido als Vicência Santos |
 | Poppy Corby-Tuech als Vinda Rosier |
 | Victoria Yeates als Bunty Broadacre |
 | Aleksandr Kuznetsov als Helmut |
 | Dave Wong als Liu Tao |
 | Fiona Glascott als Minerva McGonagall |
 | Cara Mahoney als Waitress |
 | Maja Bloom als Carrow |
 | Wilf Scolding als Frank Doyle (Workman #1) |
 | Kazeem Tosin Amore als Workman #2 |
 | Noor Dillan-Night als Workman #3 |
 | Manuel Klein als Tall Auror |
 | Valerie Pachner als Henrietta Fischer |
 | Ramona Kunze-Libnow als Edith (Elderly Matron) |
 | Lucas Englander als Horst |
 | Jan Pohl als Ministry Official |
 | Matthias Brenner als Otto |
 | Peter Simonischek als Warder |
 | Jacqueline Boatswain als Ida Webb (British Witch) |
 | David Bertrand als Victor (French Minister) |
 | Stefan Race als Karl (Dark-Eyed Waiter) |
| Jessica Cartledge als Redheaded Ravenclaw |
| Rahda Sthanakiya als Tiny Witch #1 |
| Isabelle Coverdale als Tiny Witch #2 |
 | Dónal Finn als Albert (Baker) |
| Paul Low-Hang als Zabini |
 | Hebe Beardsall als Ariana Dumbledore (uncredited) |
| David Yates | Director |
| David Heyman | Producer |
| Lionel Wigram | Producer |
| Tim Lewis | Producer |
| Steve Kloves | Producer |
| J.K. Rowling | Producer |
| Danny Cohen | Executive Producer |
| Courtenay Valenti | Executive Producer |
| Neil Blair | Executive Producer |
| George Richmond | Director of Photography |
| Steve Kloves | Screenplay |
| J.K. Rowling | Screenplay |
| James Newton Howard | Original Music Composer |
| Mark Day | Editor |
| Stuart Craig | Production Design |
| Anna Pinnock | Set Decoration |
| Daniel Hazeltine | Visual Effects |
| Alexander T.H. Browne | VFX Artist |
| Josh Berger | Executive Producer |
| Michael Sharp | Executive Producer |
| Neil Lamont | Production Design |
| Colleen Atwood | Costume Design |
| Peter Dorme | Art Direction |
| Martin Foley | Supervising Art Director |
| Oliver Goodier | Art Direction |
| Kate Grimble | Art Direction |
| Charlotte Malynn | Art Direction |
| Elicia Scales | Art Direction |
| James M. Spencer | Art Direction |
| Alastair Bullock | Supervising Art Director |
| Rosie Hardwick | Assistant Art Director |
| Olivia Muggleton | Assistant Art Director |
| Andrew Proctor | Assistant Art Director |
| Rebecca White | Assistant Art Director |
| Justin Ackroyd | Set Dresser |
| Glenn Freemantle | Supervising Sound Editor |
| Glenn Freemantle | Sound Designer |
| Katrin Arndt | Visual Effects Producer |
| Jean Bennamias | VFX Artist |
| Russell Hopwood | Visual Effects |
| Marco Lee | VFX Artist |
| Massimo Meo | Visual Effects Producer |
| Geoff Pedder | VFX Artist |
| Oliver Schulz | Visual Effects Supervisor |
| Ashlee Sutherland | Visual Effects Producer |
| Stacey Clare Richards | Set Costumer |
| Fiona Weir | Casting |
| Christian Manz | Visual Effects Supervisor |
| Michael Sharp | Unit Production Manager |
| Tim Lewis | Unit Production Manager |
| Josh Robertson | First Assistant Director |
| Josh Robertson | Associate Producer |
| David Keadell | Second Assistant Director |
| Stephen Woolfenden | Second Unit Director |
| Rowley Irlam | Stunt Coordinator |
| Roy Taylor | Stunt Coordinator |
| Alex Baily | Art Direction |
| Gary Tomkins | Art Direction |
| Paul Laugier | Art Direction |
| Huw Arthur | Art Direction |
| Tim Dutton | Assistant Art Director |
| Ann Lynch | Post Production Supervisor |
| Rob Duncan | Visual Effects Supervisor |
| Ben Barker | Supervising Sound Editor |
| Jeremy Woodhead | Makeup Designer |
| Jeremy Woodhead | Hair Designer |
| Jeremy Woodhead | Prosthetic Designer |
| Julia Vernon | Makeup Supervisor |
| Julia Vernon | Hair Supervisor |
| Laura Morse | Key Makeup Artist |
| Laura Morse | Key Hair Stylist |
| Pamela Joyce | Production Manager |
| Emma Hazell | Production Coordinator |
| Alistair Williams | Special Effects Supervisor |
| Katie Gabriel | Special Effects Coordinator |
| Alexander Fabre | Special Effects |
| Simon Rafferty | Special Effects |
| Gill Raddings | Animal Coordinator |
| Jim Weidman | Supervising Music Editor |
| Allan Jenkins | Music Editor |
| David Olson | Music Editor |
| Lucy Scarfe | Set Production Assistant |
| Niv Adiri | Sound Re-Recording Mixer |
| Andy Nelson | Sound Re-Recording Mixer |
| Johnathan Rush | Sound Re-Recording Mixer |
| Ian Tapp | Sound Re-Recording Mixer |
| Reetu Aggarwal | 3D Artist |
| Esme Coleman | Digital Compositor |
| Jessica Hooker | Stunts |
| Tolga Kenan | Stunts |
| J.K. Rowling | Original Series Creator |
| Sarah Lochlan | Stunts |
