 | Johnny Depp als Edward Scissorhands |
 | Winona Ryder als Kim |
 | Dianne Wiest als Peg |
 | Alan Arkin als Bill |
 | Anthony Michael Hall als Jim |
 | Vincent Price als The Inventor |
 | Kathy Baker als Joyce |
 | Robert Oliveri als Kevin |
 | Conchata Ferrell als Helen |
 | Caroline Aaron als Marge |
 | Dick Anthony Williams als Officer Allen |
 | O-Lan Jones als Esmeralda |
 | Susan Blommaert als Tinka |
 | Linda Perri als Cissy |
 | John Davidson als Host TV |
 | Biff Yeager als George |
 | Donna Pieroni als Blonde / TV |
 | Alan Fudge als Loan Officer |
 | Brett Rice als Reporter |
 | Marc Macaulay als Reporter |
 | Stuart Lancaster als Retired Man |
 | Steven Brill als Dishwasher Man |
 | Gina Gallagher als Granddaughter |
 | Aaron Lustig als Psychologist |
 | Peter Palmer als Editor |
| Kathy Lockwood als Neighborhood Extra |
| Linda Jean Hess als Older Woman / TV |
| Andrew B. Clark als Beefy Man |
| Bea Albano als Rich Widow / TV |
 | Marti Greenberg als Suzanne |
| Kelli Crofton als Pink Girl |
| Gary Clark als Neighborhood Extra |
| Joe Sheldon als Neighborhood Extra |
| Doyle Anderson als Neighborhood Extra |
| Carol D. Klasek als Neighborhood Extra |
| Harvey Bellman als Neighborhood Extra |
| Cecil Hawkins als Neighborhood Extra |
| Jack W. Kapfhamer als Neighborhood Extra |
| James Spicer als Neighborhood Extra |
| Jackie Carson als Neighborhood Extra |
| Carol Crumrine als Neighborhood Extra |
| Jalaine Gallion als Neighborhood Extra |
| Dianne L. Green als Neighborhood Extra |
| Ellin Dennis als Neighborhood Extra |
| Rex Fox als Police Sergeant |
| Miriam Goodspeed als Neighborhood Extra |
| Russell E. Green als Neighborhood Extra |
| Laura Nader als Neighborhood Extra |
| Mary Jane Heath als Neighborhood Extra |
| Phil Olson als Neighborhood Extra |
| Roland Douville als Neighborhood Extra |
| Tammy Boalo als Neighborhood Extra |
| Suzanne Chrosniak als Neighborhood Extra |
| Bryan Larkin als Max |
| Tim Rerucha als Van Friend (uncredited) |
 | Nick Carter als Neighborhood Extra (uncredited) |
| Danny Elfman | Original Music Composer |
| Stefan Czapsky | Director of Photography |
| Tim Burton | Producer |
| Richard Halsey | Editor |
| Colleen Atwood | Costume Design |
| Colleen Halsey | Editor |
| Victoria Thomas | Casting |
| Ve Neill | Makeup Department Head |
| Denise Di Novi | Producer |
| Tim Burton | Director |
| Tim Burton | Story |
| Caroline Thompson | Screenplay |
| Caroline Thompson | Story |
| Michael Wood | Special Effects Supervisor |
| Bo Welch | Production Design |
| Rob Whitehurst | Video Assist Operator |
| Richard Hashimoto | Executive Producer |
| Caroline Thompson | Associate Producer |
| Bill Scott | Unit Production Manager |
| Jerry Fleck | First Assistant Director |
| Francis J. Conway | Second Assistant Director |
| Tom Duffield | Art Direction |
| Cheryl Carasik | Set Decoration |
| Rick Heinrichs | Set Designer |
| Paul Sonski | Set Designer |
| Ann Harris | Set Designer |
| Chuck McSorley | Leadman |
| Frank Miller | Camera Operator |
| Zoran Veselic | First Assistant Camera |
| Warner R. Wacha | Second Assistant Camera |
| Daniel E. Teaze | Second Assistant Camera |
| Robert Ulland | Steadicam Operator |
| Jonathan Chibnall | Assistant Editor |
| Bob Badami | Music Editor |
| Petur Hliddal | Sound Mixer |
| Richard L. Anderson | Supervising Sound Editor |
| David E. Stone | Supervising Sound Editor |
| Warren Hamilton Jr. | Sound Editor |
| Michael J. Benavente | Sound Editor |
| James Christopher | Sound Editor |
| Mary Andrews | ADR Editor |
| Sonny Pettijohn | Assistant Sound Editor |
| Ralph Stuart | Assistant Sound Editor |
| Oscar Mitt | Assistant Sound Editor |
| Marilyn Bailey | Script Supervisor |
| William A. Petrotta | Property Master |
| Kevin Murphy | Chief Lighting Technician |
| Dennis J. Lootens | Rigging Gaffer |
| John Carney | Best Boy Electric |
| David A. Cook | Electrician |
| John F. Cassidy | Key Grip |
| Tom Keefer | Best Boy Grip |
| Kenny Davis | Dolly Grip |
| Ray Summers | Costume Supervisor |
| Matthew W. Mungle | Makeup Artist |
| Selena Evans-Miller | Makeup Artist |
| Brad Wilder | Makeup Artist |
| Rick Stratton | Makeup Artist |
| Yolanda Toussieng | Hair Designer |
| Lynda Kyle Walker | Hairstylist |
| Irene Aparicio | Hairstylist |
| Rick Provenzano | Hairstylist |
| Liz Spang | Hairstylist |
| Mary Ann Valdes | Assistant Hairstylist |
| Peter Kuran | Visual Effects |
| Mary Cay Hollander | Production Coordinator |
| Jacqueline A. Shea | Assistant Production Coordinator |
| Glenn Williamson | Set Production Assistant |
| John Villarino | Construction Coordinator |
| Dan Pemberton | Construction Foreman |
| John R. Elliott | Construction Foreman |
| Stephen I. Erdberg | Set Dresser |
| Michael J. Burmeister | Location Manager |
| Jory Weitz | Casting Associate |
| Glenn R. Wilder | Stunt Coordinator |
| Dan Anglin | Transportation Coordinator |
| Stanley R. Webber | Transportation Captain |
| Jay Sedrish | Production Accountant |
| Doris Hellmann | Production Accountant |
| Zade Rosenthal | Still Photographer |
| Steve Bartek | Orchestrator |
| Shawn Murphy | Scoring Mixer |
| Robert Deschaine | Foley Mixer |
| Mike Chock | Foley Editor |
| John Pospisil | Special Sound Effects |
| Steve Maslow | Sound Re-Recording Mixer |
| Stanley Kastner | Sound Re-Recording Mixer |
| Gary Ritchie | Sound Recordist |
| Kathy McCart | Sound Recordist |
| Dennis McNeill | Color Timer |
| Greg Anderson | Stunts |
| Tammy Brady Conrad | Stunts |
| Todd Bryant | Stunts |
| David Burton | Stunts |
| Gary Price | Stunts |
| Lori Lynn Ross | Stunts |
| Gar Stephen | Stunts |
| Bill Suiter | Stunts |
| Scott Wilder | Stunts |
| John Zimmerman | Stunts |
| Jon Curtis Price | Mechanical Designer |
| Jon Curtis Price | Coordinating Producer |
