 | Eddie Redmayne als Newt Scamander |
 | Katherine Waterston als Porpentina 'Tina' Goldstein |
 | Dan Fogler als Jacob Kowalski |
 | Alison Sudol als Queenie Goldstein |
 | Colin Farrell als Percival Graves |
 | Jon Voight als Henry Shaw Sr. |
 | Ron Perlman als Gnarlak |
 | Johnny Depp als Gellert Grindelwald |
 | Zoë Kravitz als Leta Lestrange |
 | Ezra Miller als Credence Barebone |
 | Samantha Morton als Mary Lou Barebone |
 | Carmen Ejogo als Seraphina Picquery |
 | Josh Cowdery als Henry Shaw Jr. |
 | Ronan Raftery als Langdon Shaw |
 | Faith Wood-Blagrove als Modesty Barebone |
 | Jenn Murray als Chastity Barebone |
 | Gemma Chan als Madame Ya Zou |
 | Peter Breitmayer als Gilbert Bingley |
 | Kevin Guthrie als Mr. Abernathy |
 | Sean Cronin als Nearby Criminal |
 | Sam Redford als Customs Official |
 | Akin Gazi als Auror |
 | Todd Boyce als The Announcer |
 | Anne Wittman als Housewife |
 | Andreea Păduraru als Auror 9 |
 | Matthew Sim als Photographer 1 |
 | Elizabeth Moynihan als Executioner #1 |
 | Adam Lazarus als Wizard |
 | Lucie Pohl als Secretary |
 | Tim Bentinck als Witness |
 | Bart Edwards als New York Chief of Police |
 | Brian F. Mulvey als The Watchman |
 | Tristan Tait als Reporter |
 | Tom Clarke Hill als Photographer 2 |
 | Cory Peterson als Bank Employee |
| Jake Samuels als Bank Guard |
| Max Cazier als Young Man |
 | Dan Hedaya als Red |
 | Christy Meyer als Guide - Inside Macusa |
| Guy Paul als Auror 2 |
 | Walles Hamonde als Auror 10 |
 | Dominique Tipper als Auror 1 |
 | Leo Heller als Boy with Birthmark |
| Miles Roughley als Poor Boy |
 | Erick Hayden als Policeman |
 | Paul Birchard als Hobo |
 | Tom Hodgkins als Barker |
 | Ellie Haddington als Mrs. Esposito |
| Joseph Macnab als Police Officer 1 |
 | Martin Oelbermann als Heinrich Eberstadt |
 | Richard Clothier als British Envoy |
 | Christian Dixon als Momolou Wotorson |
| Richard Hardisty als Auror 4 |
 | Miquel Brown als Executioner #2 |
 | Wunmi Mosaku als Beryl |
 | Cristian Solimeno als Executioner #3 |
| Matthew Wilson als Sam the Obliviator |
| Aretha Ayeh als Singer - The Blind Pig Speakeasy |
| Emmi als Singer - The Blind Pig Speakeasy |
 | Nicholas McGaughey als Australian Wizard |
 | Arinzé Kene als Auror 6 |
 | Jane Perry als Bakery Customer |
 | Abi Adeyemi als International Royal Dignitar (uncredited) |
 | Alphonso Austin als Boat Crew (uncredited) |
 | Roy Beck als Senator Shaw's Speechwriter (uncredited) |
| David J Biscoe als Journalist (uncredited) |
| Lee Bolton als Photographer (uncredited) |
| Neil Broome als Gala Dinner Guest (uncredited) |
| Fanny Carbonnel als Mrs. Goldstein (uncredited) |
| David Charles-Cully als Gentleman (uncredited) |
| Craig Davies als New Yorker (uncredited) |
| Chloe de Burgh als Tenement Woman (uncredited) |
| Paul Dewdney als New York Journalist (uncredited) |
 | Rudi Dharmalingam als Ranjit (uncredited) |
| Joshua Diffley als Young Husband (uncredited) |
| Richard Douglas als Gentleman (uncredited) |
 | Henry Douthwaite als Skender (uncredited) |
 | Dino Fazzani als Factory Worker (uncredited) |
 | Abigayle Honeywill als Criminal (uncredited) |
| Attila G. Kerekes als New York Citizen (uncredited) |
| Simon Kerrison als High Society Gentleman / Gala Guest (uncredited) |
 | Denis Khoroshko als Banker Smirnoff (uncredited) |
 | Alan Mandel als Mr. Goldstein (uncredited) |
 | Jorge Leon Martinez als Spaniard Ship Passenger (uncredited) |
 | Christine Marzano als Exterminator (uncredited) |
| Pete Meads als Factory Worker (uncredited) |
| Dennis O'Donnell als Circus Escapologist (uncredited) |
 | Gino Picciano als Gangster (uncredited) |
 | Jason Redshaw als Higher Class Gentleman (uncredited) |
| Dave Simon als New York Socialite (uncredited) |
| Connor Sullivan als Gala Guest (uncredited) |
 | Dan Trotter als Street Vendor (uncredited) |
| Morgan Walters als Watchman (uncredited) |
| Anick Wiget als Criminal on 'Wanted' Poster (uncredited) |
 | Reid Anderson als Auror (uncredited) |
 | Tineke Ann Robson als Auror (uncredited) |
 | Cinta Laura Kiehl als Candy Store Girl |
 | Annarie Boor als New Yorker (uncredited) |
| J.K. Rowling | Screenplay |
| David Yates | Director |
| Brooke Dibble | Sculptor |
| Philippe Rousselot | Director of Photography |
| James Newton Howard | Original Music Composer |
| Mark Day | Editor |
| J.K. Rowling | Producer |
| David Heyman | Producer |
| Steve Kloves | Producer |
| Lionel Wigram | Producer |
| Tim Lewis | Executive Producer |
| Neil Blair | Executive Producer |
| Rick Senat | Executive Producer |
| Colleen Atwood | Costume Design |
| Stuart Craig | Production Design |
| Fiona Weir | Casting |
| Anna Pinnock | Set Decoration |
| Anna Worley | Script Supervisor |
| Jaap Buitendijk | Still Photographer |
| David Allday | Art Direction |
| Guy Bradley | Art Direction |
| Toby Britton | Art Direction |
| Peter Dorme | Art Direction |
| Gavin Fitch | Art Direction |
| Martin Foley | Art Direction |
| Hayley Easton Street | Art Direction |
| Chris Lentz | Animation Supervisor |
| Kevin Spruce | Animation Supervisor |
| Alice Searby | Casting Associate |
| Lora Heath | Assistant Costume Designer |
| Emily Knight | Assistant Costume Designer |
| Charlotte Finlay | Costume Supervisor |
| William Evans | Set Costumer |
| Perry Goyen | Set Costumer |
| Helen Ingham | Set Costumer |
| Allan Jenkins | Music Editor |
| Karen Elliott | Music Supervisor |
| Des Whelan | Camera Operator |
| Stefan Stankowski | Camera Operator |
| Chuck Finch | Gaffer |
| Wick Finch | Gaffer |
| Jason Ewart | Steadicam Operator |
| Derek Walker | Steadicam Operator |
| Vince McGahon | Steadicam Operator |
| Laurent Laban | Animation Supervisor |
| Yvon Jardel | Animation Supervisor |
| Marco Foglia | Animation Supervisor |
| Pablo Grillo | Animation Supervisor |
| David Watkins | Special Effects Supervisor |
| Shenyan Liu | VFX Editor |
| Matthew Ozerski | VFX Editor |
| Sasha Leigh Izadpanah | VFX Editor |
| Sarah Williamson | VFX Production Coordinator |
| Eamon Yates | VFX Production Coordinator |
| Gillian Dodders | ADR & Dubbing |
| James Shannon | Dolby Consultant |
| Peter Burgis | Foley |
| Jason Swanscott | Foley |
| Simon Hayes | Production Sound Mixer |
| Ben Barker | Sound Designer |
| Eilam Hoffman | Sound Designer |
| Glenn Freemantle | Sound Designer |
| Danny Freemantle | Sound Effects Editor |
| Robert Malone | Sound Effects Editor |
| Andy Nelson | Sound Re-Recording Mixer |
| Ian Tapp | Sound Effects Editor |
| Niv Adiri | Sound Re-Recording Mixer |
| Glenn Freemantle | Supervising Sound Editor |
| Anita Burger | Hairstylist |
| Carmel Jackson | Hairstylist |
| Sally Crouch | Hairstylist |
| Rachael Speke | Hairstylist |
| Nicky Knowles | Makeup Artist |
| Laura Viana da Silva | Makeup Artist |
| Polly Mossman | Makeup Artist |
| Fae Hammond | Makeup Designer |
| Alex Rouse | Wigmaker |
| Mark Burton | First Assistant Editor |
| Hermione Byrt | First Assistant Editor |
| Josh Robertson | First Assistant Director |
| Richard Cheal | Prop Maker |
| Sarah Iovino | Art Department Coordinator |
| Lily Mathiszig-Lee | Propmaker |
| Amanda Pettett | Construction Coordinator |
| Mark Seath | Carpenter |
| Pollyanna Seath | Construction Coordinator |
| Ben Wilkinson | Property Master |
| Eunice Huthart | Stunt Coordinator |
| Ami Verge | Stunt Coordinator |
| Oscar Deeks | Epk Camera Operator |
| Steve Ellingworth | Key Grip |
| Matt Windon | First Assistant Camera |
| Shirley Nevin | Wardrobe Supervisor |
| Georgette Turner | Location Manager |
| Dan Whitty | Location Manager |
| Alejandro de la Llosa | Music Supervisor |
| David Olson | Music Editor |
| Jim Weidman | Supervising Music Editor |
| Matt Curtis | Title Designer |
| Jessica Drake | Dialect Coach |
| Teodora Ilie | Production Coordinator |
| Samantha Maggiolo | Production Coordinator |
| Liam McCartney | Armorer |
| Jill McCullough | Dialect Coach |
| Tom Ralphs | Armorer |
| Ben Rothwell | Armory Coordinator |
| Kaitlyn Smith | Production Coordinator |
| Winnie Wishart | Production Coordinator |
| Sanaz Missaghian | Costume Coordinator |
| Emmy Beech | Makeup Artist |
| Catherine Elizabeth Smith | Hairstylist |
| Katharina Hingst | Third Assistant Director |
| Katharina Hingst | Actor's Assistant |
| Robert Hladik | Stunts |
| Christian Manz | Visual Effects Supervisor |
| Tim Burke | Visual Effects Supervisor |
| Gillian Dodders | Dialogue Editor |
| James Wichall | Dialogue Editor |
| Buddie Wilkinson | Dressing Prop |
| Adrien Flanquart | VFX Artist |
| George Harris | Stunts |
| Christoph Westphal | VFX Artist |
| Nellie Burroughes | Stunt Double |
| Tom Brown | Music Arranger |
| Viktor Petrov | Director of Previsualization |
| Lucy Allen | Stunts |
| Tolga Kenan | Stunts |
| Marc Mailley | Stunts |
| Rob Bliss | Concept Artist |
| Ferran Domenech | Visual Effects Supervisor |
| J.K. Rowling | Original Series Creator |
