 | Bill Murray als Peter Venkman |
 | Dan Aykroyd als Ray Stantz |
 | Sigourney Weaver als Dana Barrett |
 | Harold Ramis als Dr. Egon Spengler |
 | Rick Moranis als Louis Tully |
 | Ernie Hudson als Winston Zeddemore |
 | Annie Potts als Janine Melnitz |
 | Peter MacNicol als Dr. Janosz Poha |
 | Harris Yulin als Judge Wexler |
 | David Margulies als Mayor Lenny |
 | Kurt Fuller als Jack Hardemeyer |
 | Janet Margolin als The Prosecutor |
 | Wilhelm von Homburg als Vigo |
 | William T. Deutschendorf als Baby Oscar |
 | Henry J. Deutschendorf II als Baby Oscar |
 | Michael P. Moran als Frank the Doorman |
| Olivia Ward als Meter Maid |
 | Mordecai Lawner als Man with a Ticket |
| Susanna Boehm als Young Woman on Crutches |
 | Mary Ellen Trainor als Brownstone Mother |
| Christopher Villaseñor als Brownstone Boy #1 |
 | Jason Reitman als Brownstone Boy #2 |
 | Aaron Lustig als Norman the Producer |
 | Page Leong als Spengler's Assistant |
 | Mark Schneider als Arguing Couple |
| Valery Pappas als Arguing Couple |
 | Catherine Reitman als Girl with Puppy |
 | Dave Florek als First Cop |
 | Richard Foronjy als Con Ed Supervisor |
 | George P. Wilbur als Bailiff |
| Sharon Kramer als Stenographer |
| Walter Flanagan als Rudy the Museum Guard |
 | Bobby Brown als Mayor's Doorman |
 | Christopher Neame als Maitre D' |
| Judy Ovitz als Slimed Restaurant Patron |
 | Tom Dugan als Restaurant Cop #1 |
| Angelo Dimascio als Restaurant Cop #2 |
 | Robert Alan Beuth als Store Manager |
 | Ralph Monaco als Police Sergeant |
| Ron Cummins als Police Lieutenant |
 | Cheech Marin als Dock Supervisor |
| Yvette Cruise als Maria, Dana's Maid |
 | John Hammil als Detective #1 |
| Ray Glanzmann als Detective #2 |
| Alex Zimmerman als Detective #3 |
 | Brian Doyle-Murray als Psychiatrist |
 | Louise Troy als Woman with Fur Coat |
 | Douglas Seale als Plaza Hotel Man |
 | Ben Stein als Public Works Official |
 | Erik Holland als Fire Commissioner |
 | Philip Baker Hall als Police Commissioner |
| Steve Baker als Telephone Man (uncredited) |
 | Trish Cook als Nun at Statue of Liberty (uncredited) |
 | Kevin Dunn als Milton Angland (uncredited) |
 | Ryan Francis als Brownstone Boy #3 (uncredited) |
| Tyra Reneé Fuller als Driver (uncredited) |
 | Jim Fyfe als Scoleri Brother / Ghost Jogger (uncredited) |
 | George Gerard als Man in Cab (uncredited) |
| Donna Guidry als Art Restoration Student (uncredited) |
| Tim Lawrence als Scoleri Brother (uncredited) |
| Peter Papageorgio als Spectator (uncredited) |
| Kariim Ratcliff als Crowd Member (uncredited) |
 | Ivan Reitman als Man Walking Outside Firehouse / Slimer (voice) (uncredited) |
| Ira S. Rosenstein als Stage Manager (uncredited) |
 | Felix Silla als Courtroom Spectator (uncredited) |
 | Max von Sydow als Vigo (voice) (uncredited) |
 | Chloe Webb als Elaine (uncredited) |
| Justin Michael Woods als Baby on the Street (uncredited) |
| Ivan Reitman | Director |
| Ivan Reitman | Producer |
| Dan Aykroyd | Screenplay |
| Harold Ramis | Screenplay |
| Danny Aiello III | Stunts |
| Randy Edelman | Original Music Composer |
| Michael Chapman | Director of Photography |
| Donn Cambern | Editor |
| Sheldon Kahn | Editor |
| Michael Chinich | Casting |
| Bo Welch | Production Design |
| Tom Duffield | Art Direction |
| Cheryl Carasik | Set Decoration |
| Gloria Gresham | Costume Design |
| Stephen Abrums | Makeup Artist |
| Gandhi Bob Arrollo | Makeup Artist |
| Frank Bianco | Hairstylist |
| John M. Elliott Jr. | Key Makeup Artist |
| Peggy Semtob | Hairstylist |
| Marlene D. Williams | Hairstylist |
| Peter Giuliano | First Assistant Director |
| Greg John Callas | Construction Coordinator |
| Rick Heinrichs | Set Designer |
| Richard Hoffenberg | Construction Foreman |
| Bill MacSems | Property Master |
| Ed Mirassou | Propmaker |
| Nick Navarro | Set Designer |
| Greg Papalia | Set Designer |
| William A. Petrotta | Property Master |
| Steve Cantamessa | Boom Operator |
| Bruce Foster | Sound Editor |
| Richard Friedman | Supervising ADR Editor |
| David M. Ice | Sound Editor |
| Chris Jargo | Dialogue Editor |
| Fred Judkins | Supervising Sound Editor |
| Tom C. McCarthy | Supervising Sound Editor |
| Solange S. Schwalbe | Sound Editor |
| Don S. Walden | Sound Editor |
| Burton Weinstein | Sound Editor |
| Pamela Easley | Visual Effects Coordinator |
| Janet Healy | Visual Effects Producer |
| Jo Martin | Visual Effects Editor |
| Dennis Muren | Visual Effects Supervisor |
| Joel Kramer | Stunt Coordinator |
| Robert Edesa | Camera Operator |
| Michael Genne | Camera Operator |
| Leslie J. Kovacs | Chief Lighting Technician |
| Bruce McBroom | Still Photographer |
| Oda Groeschel | Costume Supervisor |
| G. Tony Scarano | Costume Supervisor |
| Peter Afterman | Music Supervisor |
| Faye Brenner | Script Supervisor |
| Pamela Cederquist | Production Coordinator |
| Dan Aykroyd | Characters |
| Harold Ramis | Characters |
| Dorothy O'Leary | Casting Assistant |
| Bernie Brillstein | Executive Producer |
| Joe Medjuck | Executive Producer |
| Michael C. Gross | Executive Producer |
| Sheldon Kahn | Associate Producer |
| Gordon A. Webb | Associate Producer |
| Gordon A. Webb | Unit Production Manager |
| Christine Larson-Nitzsche | Second Assistant Director |
| Michael D. Moore | Second Unit Director |
| Larry Hezzelwood | First Assistant Camera |
| Greg Walters | Second Assistant Camera |
| Tim Sasaki | Second Assistant Camera |
| Dylan Goss | Camera Loader |
| John Warnke | Assistant Art Director |
| Chuck McSorley | Leadman |
| Jack Johnson | Production Illustrator |
| Thom Enriquez | Production Illustrator |
| Ann Harmon | Art Department Assistant |
| Tom Miller | Assistant Property Master |
| Jennifer Butler | Costumer |
| Le Dawson | Costumer |
| Adrienne Manhan | Costumer |
| Gene Kearney | Key Grip |
| Benny McNulty | Best Boy Electrician |
| Bob Munoz | Best Boy Grip |
| Eric Smith | Electrician |
| Ken W. Ballantine | Electrician |
| E. Christopher Reed | Electrician |
| Brent Poe | Electrician |
| Gregory Peters | Electrician |
| Sandy Williams | Dolly Grip |
| Robert Sordal | Dolly Grip |
| Francis N. 'Lucky' Costello | Standby Painter |
| Chuck Gaspar | Special Effects |
| Joe Day | Special Effects |
| Richard Wood | Special Effects |
| Gene S. Cantamessa | Production Sound Mixer |
| Mark Jennings | Cableman |
| Mark Gordon | Sound Editor |
| William Hartman | Sound Editor |
| Greig McRitchie | Orchestrator |
| Craig Pinkard | Transportation Coordinator |
| Dick Johnson | Transportation Captain |
| Ira S. Rosenstein | Second Second Assistant Director |
| Cyd Adams | Second Second Assistant Director |
| Ginny Warner | Production Secretary |
| Stuart Fink | Publicist |
| Matthew Gould | Production Assistant |
| Catherine Cederquist | Production Assistant |
| Anne Prager | Production Assistant |
| Stephanie Kahn | Production Assistant |
| Gaetano Vaccaro | Production Assistant |
| Jim Vatis | Production Assistant |
| David Forbes | Production Assistant |
| Mary Peters | Stunts |
| Jon Curtis Price | Special Effects |
| Steven Lambert | Stunts |
| John Dods | Makeup Artist |
| Erik Cord | Stunts |
| Kurt Bryant | Stunts |
| Bob Minor | Stunts |
| Jophery C. Brown | Stunts |
| Edmund E. Villa | Assistant Property Master |
| Tony Brubaker | Stunt Double |
| Gary J. Wayton | Stunt Double |
| Debbie Evans | Stunts |
| Andy Gill | Stunts |
| Billy D. Lucas | Stunts |
| Lane Leavitt | Stunts |
| Richard E. Butler | Stunts |
