 | Chris Pratt als Peter Quill / Star-Lord |
 | Zoe Saldaña als Gamora |
 | Dave Bautista als Drax the Destroyer |
 | Vin Diesel als Groot (voice) |
 | Bradley Cooper als Rocket (voice) |
 | Lee Pace als Ronan the Accuser |
 | Michael Rooker als Yondu Udonta |
 | Karen Gillan als Nebula |
 | Djimon Hounsou als Korath |
 | John C. Reilly als Corpsman Dey |
 | Glenn Close als Nova Prime |
 | Benicio del Toro als Taneleer Tivan / The Collector |
 | Laura Haddock als Meredith Quill |
 | Sean Gunn als Kraglin / On Set Rocket |
 | Peter Serafinowicz als Denarian Saal |
 | Christopher Fairbank als The Broker |
 | Krystian Godlewski als On Set Groot |
 | Wyatt Oleff als Young Quill |
 | Gregg Henry als Grandpa |
| Janis Ahern als Meredith's Mother |
 | Solomon Mousley als Meredith's Brother |
| Lindsay Morton als Meredith's Best Friend |
 | Robert Firth als Dr. Fitzgibbon |
 | Melia Kreiling als Bereet |
 | Tom Proctor als Horuz |
 | Nick Holmes als Horuz' Mate |
 | Max Wrottesley als Sacrificed Nova Corpsman |
 | Stan Lee als Xandarian Ladies' Man |
 | Nicole Alexandra Shipley als Pretty Xandarian |
 | Sharif Atkins als Nova Arresting Pilot |
 | Brendan Fehr als Corpsman Dey's Partner |
 | Tomas Arana als Kree Ambassador |
 | Mikaela Hoover als Nova Prime's Assistant |
 | Emmett Scanlan als Head Riot Guard |
 | Dominic Grant als Angry Guard |
 | Spencer Wilding als Mean Guard |
 | Alison Lintott als Sad Woman with Horns |
 | Alexis Rodney als Moloka Dar |
 | Nathan Fillion als Monstrous Inmate |
 | Keeley Forsyth als Mottled Prisoner |
| Frank Gilhooley als Burly Prisoner |
 | Alexis Denisof als The Other |
 | Enzo Cilenti als Watchtower Guard |
 | Richard Katz als One Legged Prisoner |
 | Ene Frost als Rifle Guard |
 | Ronan Summers als "Drop the Leg" Guard |
 | Ophelia Lovibond als Carina |
 | Laura Ortiz als Tortured Pink Girl |
 | Marama Corlett als Pit Boss |
| Rosie Jones als Lady of the Boot of Jemiah |
| Abidemi Sobande als Lady of the Boot of Jemiah |
 | Alex Rose als Lady of the Boot of Jemiah |
 | Ekaterina Zalitko als Lady of the Boot of Jemiah |
 | Emily Redding als Lady of the Boot of Jemiah |
 | Stephen Blackehart als Knowhere Dispatcher |
| Jennifer Moylan-Taylor als Sad Krylorian Girl |
 | Bruce Mackinnon als One-Eyed Ravager |
 | Ralph Ineson als Ravager Pilot |
 | Rob Zombie als Ravager Navigator (voice) |
 | Naomi Ryan als Nova Centurion |
 | John Brotherton als Nova Starblaster Pilot |
 | Graham Shiels als Alien Nova Pilot |
 | James Gunn als Maskless Sakaaran |
| Douglas Robson als Maskless Sakaaran |
 | Rachel Cullen als Corpsman Dey's Wife |
 | Isabella Poynton als Corpsman Dey's Daughter |
| Imogen Poynton als Corpsman Dey's Daughter |
 | David Yarovesky als Goth Ravager |
 | Miriam Lucia als Crying Xandarian Citizen |
 | Josh Brolin als Thanos (uncredited) |
 | Lloyd Kaufman als Prisoner (uncredited) |
 | Tyler Bates als Ravager Pilot (uncredited) |
 | Seth Green als Howard the Duck (voice) (uncredited) |
| Jozef Aoki als Kyln Prisoner (uncredited) |
 | Erica Melargo als Xandar Resident (uncredited) |
 | Rosie Jones als Lady of the Boot of Jemiah |
| Sarah Halley Finn | Casting |
| Mike Stallion | Art Direction |
| Victoria Alonso | Executive Producer |
| Kevin Feige | Producer |
| Jeremy Latcham | Executive Producer |
| Ben Davis | Director of Photography |
| Tyler Bates | Original Music Composer |
| Fred Raskin | Editor |
| Hughes Winborne | Editor |
| Craig Wood | Editor |
| Alexandra Byrne | Costume Design |
| Richard Roberts | Set Decoration |
| Stephane Ceretti | Visual Effects Supervisor |
| Simon Hayes | Production Sound Mixer |
| Lora Hirschberg | Sound Re-Recording Mixer |
| Louis D'Esposito | Executive Producer |
| Alan Fine | Executive Producer |
| Stan Lee | Executive Producer |
| Jim Barr | Assistant Art Director |
| Peter Dorme | Assistant Art Director |
| Oliver Goodier | Assistant Art Director |
| Stephen Swain | Assistant Art Director |
| Christopher Boyes | Supervising Sound Editor |
| Christopher Boyes | Sound Re-Recording Mixer |
| Matthew Wood | Supervising Sound Editor |
| David Chrastka | Sound Effects Editor |
| Susan Pickett | Visual Effects Producer |
| Steve Dent | Stunt Coordinator |
| Jay Maidment | Still Photographer |
| Dan Grace | Costume Supervisor |
| Darrell Hall | Music Editor |
| Will Kaplan | Music Editor |
| Mitul Patel | Security |
| Dan Blacklock | Set Costumer |
| Amanda Cox | Set Costumer |
| Stephanie Paul | Set Costumer |
| Kyrsten Mate | Sound Effects Editor |
| Charles Wood | Production Design |
| Dave Jordan | Music Supervisor |
| David J. Grant | Co-Producer |
| Jamie Christopher | Associate Producer |
| Cheryl Nardi | Dialogue Editor |
| Cheryl Nardi | ADR Editor |
| Brad Semenoff | Dialogue Editor |
| Brad Semenoff | ADR Editor |
| Paula Casarin | Script Supervisor |
| William B. Kaplan | Sound Mixer |
| Peter MacDonald | Second Unit Director |
| Jonathan Taylor | Second Unit Director |
| Jonathan Taylor | Second Unit Director of Photography |
| Barry Gibbs | Property Master |
| Jana Vance | Foley Artist |
| Dennie Thorpe | Foley Artist |
| Luke Dunn Gielmuda | Foley Editor |
| Kevin Sellers | Foley Editor |
| Dee Selby | Foley Editor |
| Chris Manning | Foley Recordist |
| Chris Manning | Foley Mixer |
| Jonathan Schwartz | Co-Producer |
| Nik Korda | Executive Producer |
| Hermione Ninnim | Unit Production Manager |
| Nik Korda | Unit Production Manager |
| Jamie Christopher | First Assistant Director |
| Matthew Sharp | Second Assistant Director |
| Christopher Boyes | Sound Designer |
| Matthew Wood | Sound Designer |
| Mark Swain | Art Direction |
| Thomas Brown | Art Direction |
| Jordan Crockett | Art Direction |
| Phil Sims | Visual Effects Art Director |
| Gary Spratling | "A" Camera Operator |
| Julian Morson | "B" Camera Operator |
| Sam Renton | "C" Camera Operator |
| John Ferguson | First Assistant "A" Camera |
| Leigh Gold | First Assistant "B" Camera |
| Elliot Purvis | Second Assistant "A" Camera |
| Max Glickman | Second Assistant "B" Camera |
| Tom Gough | Digital Imaging Technician |
| Jesse Torres | Post Production Supervisor |
| Steve Durkee | Supervising Music Editor |
| Meagan Costello | First Assistant Editor |
| Simon Morgan | First Assistant Editor |
| John Breinholt | First Assistant Editor |
| Emma McCleave | First Assistant Editor |
| Chris Tonick | Assistant Editor |
| Dylan Quirt | Assistant Editor |
| Heather Mullen | Assistant Editor |
| Todd Felderstein | Assistant Editor |
| Jason Solberg | VFX Editor |
| Corbin Mehl | VFX Editor |
| Nolan Reese | VFX Editor |
| Esther Bailey | VFX Editor |
| Derek Burgess | VFX Editor |
| Jennifer Bergman | Post Production Coordinator |
| Zoë Bower | Post Production Coordinator |
| Arely Talamante | Post Production Assistant |
| Hector Padilla | Post Production Assistant |
| Ryan Newberry | Third Assistant Director |
| Michela Marini | Key Set Production Assistant |
| Brittany Smith | Set Production Assistant |
| Arthur Shepherd | Set Production Assistant |
| Lebo "Boo" Motjuoadi | Production Coordinator |
| Elizabeth Small | Assistant Production Coordinator |
| Diarmuid Coghlan | Production Accountant |
| Gemma Todd | First Assistant Accountant |
| Jackie Gilbey | Payroll Accountant |
| David Smith | Gaffer |
| Warren Evans | Rigging Gaffer |
| John Fleming | Key Grip |
| Steve Hart | Location Manager |
| Peter Gray | Assistant Location Manager |
| Richard Sale | Assistant Costume Designer |
| Alison Mitchell | Assistant Costume Designer |
| Sharon Long | Assistant Costume Designer |
| Kate Chadderton | Costume Coordinator |
| Darrell Warner | Costume Illustrator |
| Warren Holder | Costume Illustrator |
| Nicholas Roche-Gordon | Key Set Costumer |
| Lucy Donowho | Set Costumer |
| Perry Goyen | Set Costumer |
| Emma Harding | Costume Assistant |
| Terry Archer | Costume Assistant |
| Paul Harvey | Costume Assistant |
| Elizabeth Yianni-Georgiou | Makeup Designer |
| Elizabeth Yianni-Georgiou | Hair Designer |
| Vera Steimberg | Makeup Artist |
| Susie Redfern | Makeup Artist |
| Andrew Simonin | Hair Supervisor |
| Debbi Salmon | Makeup & Hair |
| Claire Burgess | Makeup & Hair |
| Nicky Knowles | Makeup & Hair |
| Charlie Hounslow | Makeup & Hair |
| Catriona Johnstone | Makeup & Hair |
| Helena Card | Makeup Trainee |
| Carol Waugh | Wigmaker |
| Peter James | Standby Art Director |
| Oliver Carroll | Assistant Art Director |
| Jennifer Bowes | Art Department Coordinator |
| Claire Shakespeare | Art Department Assistant |
| Jessica Goodall | Art Department Assistant |
| Daisy Meyer | Art Department Assistant |
| Jane Wu | Storyboard Artist |
| Tim Divar | Storyboard Artist |
| David Krentz | Storyboard Artist |
| Thomas A. Nelson | Storyboard Artist |
| Bryan Andrews | Storyboard Artist |
| Daniel Andrews | Storyboard Artist |
| Lucy Eyre | Assistant Set Decoration |
| Guy Mount | Assistant Set Decoration |
| Alan Payne | Art Direction |
| Neil Floyd | Graphic Designer |
| Reg Poerscout-Edgerton | Local Casting |
| Stacy Mann | Publicist |
| Tamara Hunter | Casting Associate |
| Jason B. Stamey | Casting Assistant |
| Kathleen Chopin | Casting Consultant |
| Jeremy Emerman | Epk Camera Operator |
| John Bohan | Construction Manager |
| Tracy Low | Construction Coordinator |
| Darryl Paterson | Assistant Property Master |
| Paul Corbould | Special Effects Supervisor |
| Alicia Davies | Special Effects Coordinator |
| David White | Makeup Effects Designer |
| Susie Redfern | Special Effects Makeup Artist |
| Valentina Visintin | Special Effects Makeup Artist |
| Jessica Brooks | Special Effects Makeup Artist |
| Jane O'Kane | Special Effects Makeup Artist |
| Nelly Guimaras | Special Effects Makeup Artist |
| Victoria Bancroft | Special Effects Makeup Artist |
| Peter Devlin | Transportation Captain |
| David Acord | Sound Designer |
| David Acord | Sound Effects Editor |
| Jonathan Borland | Assistant Sound Editor |
| Danielle Dupre | Sound Re-Recording Assistant |
| Stephen Urata | Sound Re-Recording Assistant |
| Tony Sereno | Sound Re-Recording Assistant |
| James Wright | Dolby Consultant |
| Doc Kane | ADR Mixer |
| Jeff Gersh | ADR Mixer |
| Jeanette Browning | ADR Recordist |
| Barbara Harris | ADR Voice Casting |
| Tim Williams | Additional Music |
| Dieter Hartmann | Additional Music |
| Tim Williams | Orchestrator |
| Drew Krassowski | Orchestrator |
| Margaret Gardner | Music Coordinator |
| Robert Hladik | Stunts |
| Andy Park | Conceptual Illustrator |
| Jonathan Fawkner | Visual Effects Supervisor |
| Nicolas Aithadi | Visual Effects Supervisor |
| Ray Chan | Supervising Art Director |
| Peter G. Travers | Visual Effects Supervisor |
| James Gunn | Director |
| James Gunn | Writer |
| Nicole Perlman | Writer |
| Andy Lanning | Comic Book |
| Dan Abnett | Comic Book |
| Jerad Marantz | Concept Artist |
| Maciej Kuciara | Concept Artist |
| Rick James | Camera Trainee |
| Val Mayerik | Characters |
| Steve Gerber | Characters |
| Christoph Roth | Visual Effects Producer |
| Bill Mantlo | Characters |
| Keith Giffen | Characters |
| Jim Starlin | Characters |
| Steve Englehart | Characters |
| Steve Gan | Characters |
| Arnold Drake | Thanks |
| Gene Colan | Thanks |
| Timothy Green II | Thanks |
| Roger Stern | Thanks |
| John Buscema | Thanks |
| Sal Buscema | Thanks |
| Stan Lee | Thanks |
| Don Heck | Thanks |
| Jack Kirby | Thanks |
| Mike Friedrich | Thanks |
| Marko Djurdjevic | Thanks |
| Marv Wolfman | Thanks |
| Paul Pelletier | Thanks |
| Caitlin Dechelle | Stunts |
| Lisa Wong | Set Costumer |
| Willis Chung | Digital Imaging Technician |
| Weston Middleton | Production Assistant |
| Gui DaSilva-Greene | Stunts |
| Dani Biernat | Stunt Double |
| Chris Brewster | Stunts |
| Chloé Bruce | Stunt Double |
| Rob de Groot | Stunt Double |
| Maria Dent | Stunts |
| Ryan Dent | Stunts |
| Sam Dent | Stunts |
| Zack Duhame | Stunts |
| Holland Diaz | Stunts |
| Danny Euston | Stunts |
| Clay Donahue Fontenot | Stunts |
| Oliver Gough | Stunt Double |
| Thomas Robinson Harper | Stunt Coordinator |
| Reid Harper | Stunts |
| Rowley Irlam | Stunt Coordinator |
| David R. Grant | Stunt Double |
| Paul Howell | Stunts |
| David Hugghins | Stunts |
| Matt Leonard | Stunts |
| Tara Macken | Stunt Double |
| Kim McGarrity | Fight Choreographer |
| Maurice Lee | Stunts |
| Sian Milne | Stunt Double |
| Brandon Melendy | Stunts |
| Jan Petřina | Stunt Double |
| Rory Mulroe | Stunts |
| Dominic Preece | Stunts |
| Rashid Phoenix | Stunts |
| Shawn Robinson | Stunts |
| Douglas Robson | Stunt Double |
| Daniel Stevens | Stunt Double |
| Helen Steinway Bailey | Stunts |
| Mens-Sana Tamakloe | Stunts |
| Nico Woulard | Stunts |
| Leo Woodruff | Stunts |
| Annabel Wood | Stunts |
| Kofi Yiadom | Stunts |
| Ben Wright | Stunt Double |
| Monique Ganderton | Stunt Double |
| Casey O'Neill | Stunts |
