 | Nick Swardson als Remy (voice) |
 | T.J. Miller als Augie (voice) |
 | Mila Kunis als Deema (voice) |
 | Bob Odenkirk als The Devil (voice) |
 | Susan Sarandon als Barb the Angel (voice) |
 | Danny McBride als Orpheus (voice) |
 | Rob Riggle als Curt (voice) |
 | Jennifer Coolidge als Durmessa (voice) |
 | Michael Peña als Abigor (voice) |
 | Kumail Nanjiani als Dave the Demon (voice) |
 | J.B. Smoove als Sal the Demon (voice) |
 | David Koechner als Asmodeus (voice) |
 | Paul Scheer als Head Demon (voice) |
 | Brian Posehn als Cleb (voice) |
 | Kerri Kenney als Madame Zonar (voice) |
 | H. Jon Benjamin als The Tree |
 | Dana Snyder als Garthog (voice) |
 | Jay Johnston als Rick (voice) |
 | Maria Bamford als Gloria (voice) |
 | Lance Bass als Darren (voice) |
 | John Farley als Demon (voice) |
 | Seth Morris als Atheist (voice) |
 | Greg Proops als Asmoday (voice) |
 | Kyle Kinane als Demon Head (voice) |
 | Paul F. Tompkins als Annoyed Lost Soul |
| Tom Gianas | Director |
| Ross Shuman | Director |
| Hugh Sterbakov | Writer |
| Zeb Wells | Writer |
| Stephen Ananicz | Executive Producer |
| Eric Blyler | Producer |
| Alexander Bulkley | Producer |
| Corey Campodonico | Producer |
| Tankut Eker | Executive Producer |
| Victoria L. Howard | Co-Producer |
| Ryan Franks | Music |
| Scott Nickoley | Music |
| Matt Mariska | Editor |
| Mary Hidalgo | Casting |
| Jamie Thomason | Casting |
| Kyle Arneson | Production Design |
| Kyle Arneson | Art Direction |
| Jeanette Moffat | Costume Design |
| Andrew Babick | Production Manager |
| Debi Cohen | Production Manager |
| Greg Cahill | Assistant Director |
| Noah Sage Amrani | Art Department Manager |
| Tom Borowski | Art Department Manager |
| Lauren R. Brown | Art Department Manager |
| Matt Burlingame | Modeling |
| Brian Capati | Art Department Manager |
| Brian Dooley | Sculptor |
| Pia Dulu | Modeling |
| Frank Duran | Modeling |
| Samantha Fawaz | Interior Designer |
| Caroline Foley | Art Department Manager |
| Jennifer Hogan | Art Department Manager |
| Teresa Pilar Huarte | Modeling |
| Peter Keahey | Storyboard |
| Joe Kennedy | Storyboard |
| Melissa Krystofiak | Digital Producer |
| Tennessee Reid Norton | Art Department Manager |
| Logan Payne | Modeling |
| Rob Ronning | Art Department Manager |
| Gregory Sesma | Storyboard |
| Katy Stafford | Art Department Manager |
| David Tuber | Storyboard |
| Jon Uttenreither | Construction Coordinator |
| Richard Van As | Modeling |
| Yaoyao Ma Van As | Storyboard |
| Christopher Robert Watson | Modeling |
| Jeff White | Modeling |
| Robyn Yannoukos | Art Department Manager |
| Scott Cannizzaro | ADR & Dubbing |
| Emilie Corpuz | Sound Editor |
| Hunter Curra | Supervising Sound Editor |
| Joy Elett | Sound Editor |
| Ryan Franks | Sound Designer |
| Scott A. Jennings | Sound Re-Recording Mixer |
| Scott Nickoley | Sound Designer |
| Jillinda Palmer | Sound Editor |
| Dan Snow | Other |
| Ethan Walter | Dialogue Editor |
| Noah Sage Amrani | Visual Effects |
| Andrew Babick | Compositors |
| Matthew Collorafice | Visual Effects Supervisor |
| Ashley-Martin Dunn | Compositors |
| Paul Evangelista | Compositors |
| Tyler A. Hawes | Visual Effects |
| Tyler A. Hawes | Visual Effects Supervisor |
| John Ikuma | Compositors |
| Lars C. Larsen | Rigging Grip |
| Hae-Joon Lee | Visual Effects |
| Cam Leeburg | Visual Effects Producer |
| Teresa Leong | Visual Effects |
| Tiffanie Mang | Visual Effects |
| Thomas McVay | Visual Effects |
| Scott Purdy | Digital Producer |
| Andrew Racho | Compositors |
| Trent Smith | Visual Effects Producer |
| Shanan Sussman | Visual Effects |
| Takashi Takeoka | Compositors |
| Geno Tazioli | Executive Producer |
| Richard Van As | Compositors |
| Yaoyao Ma Van As | Compositors |
| Andy Windak | Compositors |
| Laura Yilmaz | Compositors |
| Frank Duran | Lighting Camera |
| Teresa Leong | Lighting Manager |
| Drex Reed | Lighting Technician |
| Kristina M. Schulte-Eversum | Lighting Technician |
| Jordan Tremayne | Gaffer |
| Sarah Abel | Animation |
| Noah Sage Amrani | Animation |
| Andy Bialk | Art Department Manager |
| Kim Blanchette | Animation |
| Bob Blevins | Animation |
| Musa Brooker | Animation |
| Christopher Calvi | Animation |
| Webster Colcord | Animation |
| Tyson James Dale | Animation |
| Dan Driscoll | Animation |
| Nicole Emmons | Animation |
| Adam Fisher | Animation |
| Heidi Flick | Animation Manager |
| Kevin Glick | Animation |
| Angie Glocka | Animation |
| Drayson Helberg | Animation |
| Drew Hodges | Animation |
| Cean Huckabay | Animation |
| Owen Klatte | Animation |
| Misha Klein | Animation Director |
| Rachel Larsen | Animation |
| Celeste Leipham | Animation |
| Hilary Lile | Animation |
| Sihanouk Mariona | Animation |
| Michael Parks | Animation |
| Aaron Preacher | Animation |
| Justin M. Rasch | Animation |
| Jessica Rather | Animation |
| Gregory Sesma | Animation |
| Sarah Tejeda | Animation |
| Don Waller | Animation |
| Ben Zelkowicz | Animation |
| D. Bonadona | Costume Design |
| Daniella Cartun | Costume Supervisor |
| Jessica Dalva | Costume Design |
| Stephanie Helms | Costume Design |
| Jocelyn Lynch | Costume Design |
| Nick Willard | Editorial Manager |
| Michael Williams | Editorial Manager |
| Ryan Franks | Music Editor |
| Margaret Saadi Kramer | Music Editor |
| Wayne Kramer | Songs |
| Scott Nickoley | Music Editor |
| Juan Ponciano | Music Editor |
| Devin Roth | Score Engineer |
| Aleks von Korff | Score Engineer |
| Richard Ziegler | Music Editor |
| Monica Ahanonu | Production Intern |
| George Aldridge | Other |
| Liz Allen | Art Department Manager |
| Kenneth Bridges | Other |
| Greg Cahill | Production Manager |
| Robert Hartmann | Production Accountant |
| Carly Hustedt | Production Intern |
| Angeline Izquierdo | Production Intern |
| Debra Moore | Production Manager |
| Dan Nunan | Production Office Assistant |
| Melissa Piekaar | Production Intern |
| Kelly Prow | Art Department Manager |
| Nikki Rice | Sculptor |
| Jenna Roadman | Production Office Coordinator |
| Florian Schereck | Production Controller |
| Kirk Scott | Production Supervisor |
| Rich Zim | Animation |
| Eric Adkins | Director of Photography |
| Owen Klatte | Visual Effects |
