 | Al Pacino als Will Dormer |
 | Robin Williams als Walter Finch |
 | Hilary Swank als Ellie Burr |
 | Martin Donovan als Hap Eckhart |
 | Nicky Katt als Fred Duggar |
 | Maura Tierney als Rachel Clement |
 | Paul Dooley als Chief Nyback |
 | Jonathan Jackson als Randy Stetz |
 | Katharine Isabelle als Tanya Francke |
 | Larry Holden als Farrell |
 | Jay Brazeau als Francis |
 | Kerry Sandomirsky als Trish Eckhart |
 | Yan-Kay Crystal Lowe als Kay Connell |
 | Lorne Cardinal als Rich |
 | Paula Shaw als Coroner |
 | Oliver 'Ole' Zemen als Pilot |
 | Tasha Simms als Mrs. Connell |
| Malcolm Boddington als Principal |
| James Hutson als Officer #1 |
| Andrew Campbell als Officer #2 |
 | Emily Perkins als Girl at Funeral |
 | Dean Wray als Ticket Taker |
 | Chris Gauthier als Uniformed Officer |
| Kate Robbins als Woman on the Road |
 | Ian Tracey als Warfield (voice) |
| Hillary Seitz | Screenplay |
| George Clooney | Executive Producer |
| Dody Dorn | Editor |
| Marci Liroff | Casting |
| Nathan Crowley | Production Design |
| Michael Diner | Art Direction |
| Peter Lando | Set Decoration |
| Tish Monaghan | Costume Design |
| Broderick Johnson | Producer |
| Steven P. Wegner | Associate Producer |
| David Julyan | Original Music Composer |
| Andrew A. Kosove | Producer |
| Edward McDonnell | Producer |
| Paul Junger Witt | Producer |
| Ben Cosgrove | Associate Producer |
| Steven Soderbergh | Executive Producer |
| Charles J.D. Schlissel | Executive Producer |
| Kim Roth | Executive Producer |
| Wally Pfister | Director of Photography |
| Rob McEwan | Still Photographer |
| Kelly Moon | Script Supervisor |
| Eva Morgan | Production Coordinator |
| Curt Schulkey | Supervising Sound Editor |
| Aaron Glascock | Supervising Sound Editor |
| Tony Giacinti | Boom Operator |
| Myron Nettinga | Sound Re-Recording Mixer |
| Michael Minkler | Sound Re-Recording Mixer |
| Franziska Keller | Art Department Coordinator |
| Keith Woods | Rigging Gaffer |
| Andrew W. Davidson | Gaffer |
| Ken Kirzinger | Stunt Coordinator |
| Randy Shymkiw | Special Effects Coordinator |
| Karin Nosella | Assistant Costume Designer |
| Sandra Watson | Costume Supervisor |
| Alex Gibson | Music Editor |
| Steven A. Adelson | Steadicam Operator |
| Erik Skjoldbjærg | Original Film Writer |
| Nikolaj Frobenius | Original Film Writer |
| Larry Sutton | Sound Mixer |
| Alexandra Gonzales | Dialogue Editor |
| Kira Roessler | Dialogue Editor |
| Alicia Stevenson | Foley Artist |
| Dawn Fintor | Foley Artist |
| David Betancourt | Foley Mixer |
| Thom Brennan | Foley Editor |
| Dan Sissons | Property Master |
| Glen Lougheed | Location Scout |
| Marvin Walowitz | Sound Effects Editor |
| George Simpson | Sound Effects Editor |
| Stephanie Boeke | Extras Casting |
| Susan Taylor Brouse | Local Casting |
| Lynne Carrow | Local Casting |
| Dan Perri | Title Designer |
| Christopher Nolan | Director |
| Lauro David Chartrand-DelValle | Stunt Double |
