 | Tom Cruise als Lestat |
 | Brad Pitt als Louis |
 | Antonio Banderas als Armand |
 | Christian Slater als Malloy |
 | Stephen Rea als Santiago |
 | Kirsten Dunst als Claudia |
 | Domiziana Giordano als Madeleine |
 | Thandiwe Newton als Yvette |
 | Indra Ové als New Orleans Whore |
 | Laure Marsac als Mortal Woman on Stage |
 | Virginia McCollam als Whore on Waterfront |
 | John McConnell als Gambler |
| Mike Seelig als Pimp |
 | Bellina Logan als Tavern Girl |
 | Lyla Hay Owen als Widow St. Clair |
| Lee E. Scharfstein als Widow's Lover |
 | Helen McCrory als 2nd Whore |
| Monte Montague als Plague Victim Bearer |
| Nathalie Bloch als Maid |
| Jeanette Kontomitras als Woman in Square |
 | Roger Lloyd Pack als Piano Teacher |
| George Kelly als Dollmaker |
| Nicole DuBois Favre als Creole Woman |
 | Micha Bergese als Paris Vampire |
| Rory Edwards als Paris Vampire |
 | Marcel Iureș als Paris Vampire |
 | Susan Lynch als Paris Vampire |
 | Louise Kim Salter als Paris Vampire |
 | Matthew Sim als Paris Vampire |
 | François Testory als Paris Vampire |
 | Andrew Tiernan als Paris Vampire |
| Simon Tyrrell als Paris Vampire |
 | George Antoni als Paris Vampire |
 | Sara Stockbridge als Estelle |
 | Katia Caballero als Woman in Audience |
| Louis Lewis-Smith als Mortal Boy |
| Anne Rice | Screenplay |
| David Geffen | Producer |
| Stephen Woolley | Producer |
| Elliot Goldenthal | Original Music Composer |
| Philippe Rousselot | Director of Photography |
| Mick Audsley | Editor |
| Joke van Wijk | Editor |
| Susie Figgis | Casting |
| Juliet Taylor | Casting |
| Dante Ferretti | Production Design |
| Francesca Lo Schiavo | Set Decoration |
| Sandy Powell | Costume Design |
| Sandrine Ageorges | Unit Production Manager |
| Neil Jordan | Director |
| Ansel M. Stroud Jr. | Thanks |
| Redmond Morris | Co-Producer |
| Stephen McLaughlin | Scoring Mixer |
| Matthias Gohl | Music Score Producer |
| Anne Rice | Novel |
| River Phoenix | In Memory Of |
| Gary Archer | Prosthetics |
| Stan Winston | Makeup Effects Designer |
| Patrick Clayton | First Assistant Director |
| Philip Kohler | Unit Production Manager |
| Michael Stevenson | Second Assistant Director |
| Jean-Pierre Avice | Unit Production Manager |
| Chris Brigham | Unit Production Manager |
| John Engel | Unit Production Manager |
| Joe Burns | Second Assistant Director |
| Robert Legato | Visual Effects Supervisor |
| Robert Legato | Second Unit Director |
| Greg Powell | Stunt Coordinator |
| Nick Gillard | Stunts |
| Mark Dalton | Stunts |
| Laura Dash | Stunts |
| Sy Holland | Stunts |
| Mark Southworth | Stunts |
| Paul Jennings | Stunts |
| Mark Lisbon | Stunts |
| Andreas Petrides | Stunts |
| Gary Powell | Stunts |
| Lee Sheward | Stunts |
| Anastas N. Michos | Camera Operator |
| Clive Winter | Sound Mixer |
| Malcolm Middleton | Supervising Art Director |
| Diana Dill | Script Supervisor |
| Michèle Burke | Makeup Supervisor |
| Michèle Burke | Makeup Artist |
| Yves De Bono | Special Effects Supervisor |
| Mark Clayton | Third Assistant Director |
| Ros Shingleton | Assistant Set Decoration |
| Ken Court | Assistant Art Director |
| Stephen Scott | Assistant Art Director |
| Eddy Joseph | Supervising Sound Editor |
| Peter Joly | Sound Editor |
| Nigel Mills | Sound Editor |
| Michael Connell | Music Editor |
| Peter Holt | Foley Editor |
| Tom Fleischman | Sound Re-Recording Mixer |
| Robin O'Donoghue | Sound Re-Recording Mixer |
| Dean Humphreys | Sound Re-Recording Mixer |
| Carol Schwartz | Key Makeup Artist |
| Carol Schwartz | Makeup Artist |
| Nick Dudman | Makeup Artist |
| Nick Dudman | Key Makeup Artist |
| Sarah Monzani | Key Makeup Artist |
| Sarah Monzani | Makeup Artist |
| Morag Ross | Makeup Artist |
| Morag Ross | Key Makeup Artist |
| Jan Archibald | Hair Department Head |
| Michael White | Key Hair Stylist |
| Eithné Fennel | Key Hair Stylist |
| Frank Gardiner | Assistant Costume Designer |
| John Scott | Costume Supervisor |
| Kevin De La Noy | Second Unit First Assistant Director |
| David Carrigan | Additional Second Assistant Director |
| Micha Bergese | Choreographer |
| Chris Corbould | Special Effects Supervisor |
| Trevor Neighbour | Special Effects Supervisor |
| Susan E. Fiore | Second Second Assistant Director |
| Paul Bernard | Additional Second Assistant Director |
| James Devis | Second Unit Director |
| Alan Tomkins | Art Direction |
| Kevin Constant | Assistant Art Director |
| Robert Perdziola | Assistant Art Director |
| Stella Vaccaro | Set Designer |
| Monroe Kelly | Set Designer |
| Deirdre N. Williams | Costume Supervisor |
| Tammy Kusian | Hairstylist |
| James E. Tocci | Art Direction |
| David B. Nowell | Camera Operator |
| Jean-Philippe Blime | Assistant Director |
| Dominique Delany | Second Assistant Director |
| Jean-Michel Hugon | Art Direction |
| Jean-Michel Ducourty | Assistant Art Director |
| Peter Takeuchi | Visual Effects Producer |
| John Rosengrant | Makeup Designer |
| Shane Mahan | Makeup Designer |
| George Fenton | Music Supervisor |
