 | Bryan Cranston als Chief (voice) |
 | Koyu Rankin als Atari Kobayashi (voice) |
 | Bob Balaban als King (voice) |
 | Edward Norton als Rex (voice) |
 | Bill Murray als Boss (voice) |
 | Jeff Goldblum als Duke (voice) |
 | Kunichi Nomura als Mayor Kobayashi (voice) |
 | Fisher Stevens als Scrap (voice) |
 | Akira Takayama als Major Domo (voice) |
 | Greta Gerwig als Tracy Walker (voice) |
 | Ken Watanabe als Head Surgeon (voice) |
 | Frances McDormand als Interpreter Nelson (voice) |
 | Nijiro Murakami als Editor Hiroshi (voice) |
 | Harvey Keitel als Gondo (voice) |
 | Liev Schreiber als Spots (voice) |
 | Scarlett Johansson als Nutmeg (voice) |
 | Tilda Swinton als Oracle (voice) |
 | Akira Ito als Professor Watanabe (voice) |
 | F. Murray Abraham als Jupiter (voice) |
 | Courtney B. Vance als Narrator (voice) |
 | Yoko Ono als Assistant-Scientist Yoko-ono (voice) |
 | Mari Natsuki als Auntie (voice) |
 | Yojiro Noda als News Anchor (voice) |
 | Frank Wood als Simul-Translate Machine (voice) |
 | Roman Coppola als Igor (voice) |
 | Anjelica Huston als Mute Poodle (voice) |
 | Kara Hayward als Peppermint (voice) |
| Satoshi Yamazaki als Taiko Drummer (voice) |
| Gen Ueda als Taiko Drummer (voice) |
 | Ryuhei Matsuda als Junior Scientist 4 / Bartender (voice) |
| Jun Takahashi als Mission Control Drone Pilot (voice) |
| Edward Bursch als Owl (voice) |
| Luli Shioi als Mission Control Technician (voice) |
| Erica Dorn als Mission Control Technician (voice) |
| Chinami Narikawa als Mission Control Technician (voice) |
| Chris Benz als Aboriginal Dog (voice) |
| Alex Orman als Aboriginal Dog (voice) |
| J. Wurster als Aboriginal Dog (voice) |
 | Jake Ryan als Junior-Interpreter Ernie (voice) |
 | Takayuki Yamada als Junior Scientist 1 (voice) |
| Kozue Akimoto als Junior Scientist 2 (voice) |
 | Shota Matsuda als Junior Scientist 3 (voice) |
| Kiyotaka Mizukoshi als Election Night Tabulator (voice) |
 | Elaiza Ikeda als Punk Girl (voice) |
| Ryuhei Nakadai als Surgical Assistant (voice) |
| Shin Mononobe als Surgical Assistant (voice) |
| Ikunosuke als Daily Manifesto Student (voice) |
| Taichi Kodama als Daily Manifesto Student (voice) |
| Karin Okoso als Daily Manifesto Student (voice) |
| Wes Anderson | Director |
| Wes Anderson | Writer |
| Wes Anderson | Producer |
| Tim Allen | Animation |
| Adam Stockhausen | Production Design |
| Alexandre Desplat | Original Music Composer |
| Charlie Woebcken | Executive Producer |
| Douglas Aibel | Casting |
| Edward Bursch | Editor |
| Steven M. Rales | Producer |
| Tristan Oliver | Director of Photography |
| Paul Harrod | Production Design |
| Ralph Foster | Editor |
| Scott Rudin | Producer |
| Jeremy Dawson | Producer |
| Henning Molfenter | Executive Producer |
| Kunichi Nomura | Casting |
| Christoph Fisser | Executive Producer |
| Curt Enderle | Art Direction |
| Eli Bush | Executive Producer |
| Cristina Acuña | Set Dresser |
| Octavia Peissel | Co-Producer |
| David Greenbaum | Production Director |
| Chris Scarabosio | Sound Re-Recording Mixer |
| Wayne Lemmer | Sound Re-Recording Mixer |
| John Peet | Associate Producer |
| Eli Bush | Co-Producer |
| Molly Cooper | Consulting Producer |
| Ben Adler | Associate Producer |
| Angela Poschet | Production Supervisor |
| Gisela Evert | Post Production Supervisor |
| Alex Moffat | Third Assistant Director |
| Francesca Alberigi | Third Assistant Director |
| Alan Halls | Third Assistant Director |
| Andrew Weisblum | Supervising Film Editor |
| James Emmott | First Assistant Director |
| Emily Stevens | Third Assistant Director |
| Roman Coppola | Story |
| Kunichi Nomura | Story |
| Jason Schwartzman | Story |
| Wes Anderson | Story |
| Kevin Timon Hill | Assistant Art Director |
| Gwenn Germain | Animation Director |
| Duncan Gist | 2D Artist |
| Mark Lacey | Second Assistant Director |
| Pamela Pifferi | Production Assistant |
| Aya Suzuki | Senior Animator |
