 | Spencer Tracy als C. G. Culpepper |
 | Milton Berle als J. Russell Finch |
 | Sid Caesar als Melville Crump |
 | Buddy Hackett als Benjy Benjamin |
 | Ethel Merman als Mrs. Marcus |
 | Mickey Rooney als Ding 'Dingy' Bell |
 | Dick Shawn als Sylvester Marcus |
 | Phil Silvers als Otto Meyer |
 | Terry-Thomas als J. Algernon Hawthorne |
 | Jonathan Winters als Lennie Pike |
 | Edie Adams als Monica Crump |
 | Dorothy Provine als Emeline Marcus-Finch |
 | Eddie 'Rochester' Anderson als Second Cab Driver |
 | Jim Backus als Tyler Fitzgerald |
 | Ben Blue als Biplane Pilot |
 | Joe E. Brown als Union Official |
 | Alan Carney als Police Sergeant |
 | Chick Chandler als Detective Outside Chinese Laundromat |
 | Barrie Chase als Sylvester's Girlfriend |
 | Lloyd Corrigan als The Mayor |
 | William Demarest als Police Chief Aloysius |
 | Selma Diamond als Ginger Culpepper (voice) |
 | Andy Devine als Sheriff of Crockett County |
 | Peter Falk als Third Cab Driver |
 | Norman Fell als Detective at Grogan's Crash Site |
 | Paul Ford als Col. Wilberforce |
 | Stan Freberg als Deputy Sheriff |
 | Louise Glenn als Billie Sue Culpepper (voice) |
 | Leo Gorcey als First Cab Driver |
 | Sterling Holloway als Fire Chief |
 | Marvin Kaplan als Irwin |
 | Edward Everett Horton als Mr. Dinckler |
 | Buster Keaton als Jimmy the Crook |
 | Charles Lane als Airport Manager |
 | Don Knotts als Nervous Motorist |
 | Mike Mazurki als Miner |
 | Charles McGraw als Lt. Matthews |
 | Cliff Norton als Reporter |
 | Zasu Pitts als Gertie - Switchboard Operator |
 | Carl Reiner als Tower Controller at Rancho Conejo |
 | Madlyn Rhue als Secretary Schwartz |
 | Roy Roberts als Policeman Outside Irwin & Ray's Garage |
 | Arnold Stang als Ray |
 | Nick Stewart als Driver run off highway |
 | Moe Howard als Airport Firemen #1 |
 | Larry Fine als Airport Firemen #2 |
 | Joe DeRita als Airport Firemen #3 |
 | Sammee Tong als Laundryman |
 | Jimmy Durante als Smiler Grogan |
 | Jack Benny als Man in Car in Desert (uncredited) |
 | Jerry Lewis als Driver Who Runs Over Hat (uncredited) |
 | Doodles Weaver als Hardware Store Clerk (uncredited) |
 | Jesse White als Air Traffic Controller |
 | Al Bain als Spectator (uncredited) |
 | Stanley Clements als Reporter (uncredited) |
| Max Wagner als Spectator (uncredited) |
 | Morey Amsterdam als Uncle Mike (voice) (uncredited) |
| Lovyss Bradley als Matron (uncredited) |
| Dick Cherney als Detective (uncredited) |
 | John Clarke als Helicoper Pilot (uncredited) |
 | Roy Engel als Patrolman / Police Radio Voice Unit F-14 (uncredited) |
 | Nicholas Georgiade als Detective at Grogan's Crash Site (uncredited) |
 | Stacy Harris als Police Radio Unit F-7 (voice) (uncredited) |
 | Don C. Harvey als Policeman in Helicopter (uncredited) |
| John Indrisano als Hard Hat in Crowd (uncredited) |
 | Allen Jenkins als Cop (uncredited) |
 | Tom Kennedy als Traffic Cop (uncredited) |
 | Charles Sherlock als Crowd Member (uncredited) |
| Paul Sorensen als Hardhat in Crowd Next to Joe E Brown. (uncredited) |
 | Lennie Weinrib als F-14 / Ladder Fireman (voice) (uncredited) |
| Stanley Kramer | Director |
| William Rose | Screenplay |
| Tania Rose | Screenplay |
| Stanley Kramer | Producer |
| Ernest Gold | Original Music Composer |
| Ernest Laszlo | Director of Photography |
| Gene Fowler Jr. | Editor |
| Robert C. Jones | Editor |
| Frederic Knudtson | Editor |
| Rudolph Sternad | Production Design |
| Gordon Gurnee | Art Direction |
| Joseph Kish | Set Decoration |
| Bill Thomas | Costume Design |
| George Lane | Makeup Artist |
| Lynn F. Reynolds | Makeup Artist |
| Bud Westmore | Makeup Artist |
| Paul Mantz | Aerial Coordinator |
| Frank Tallman | Aerial Coordinator |
| Ivan Volkman | Other |
| Anne P. Kramer | Producer's Assistant |
| Clem Beauchamp | Production Manager |
| John K. Kean | Sound Engineer |
| Walter Elliott | Sound Editor |
| Bud Pine | Production Coordinator |
| Bert Chervin | Assistant Director |
| George R. Batcheller Jr. | Assistant Director |
| Charles Scott | Assistant Director |
| Charles F. Wheeler | Camera Operator |
| Dick Johnson | Assistant Camera |
| Joe King | Costume Supervisor |
| Art Dunham | Music Editor |
| Morris Rosen | Grip |
| Marshall Schlom | Script Supervisor |
| Joseph Edesa | Gaffer |
| Martin Kashuk | Assistant Grip |
| Art Cole | Property Master |
| Clem Portman | Sound Re-Recording Mixer |
| Roy Granville | Sound Re-Recording Mixer |
| Vinton Vernon | Sound Re-Recording Mixer |
| Connie Nichols | Hairdresser |
| Saul Bass | Title Designer |
| Carey Loftin | Stunt Coordinator |
| Irman Roberts | Additional Photography |
| Hal McAlpin | Additional Photography |
| Farciot Edouart | Visual Effects |
| Linwood G. Dunn | Visual Effects |
| James Gordon | Visual Effects |
| Danny Lee | Special Effects |
| Ernest Gold | Songs |
| Mack David | Songs |
| William Rose | Story |
| Tania Rose | Story |
| Buddy Van Horn | Stunts |
| Loren Janes | Stunt Double |
| Bob Herron | Stunts |
| Paul Baxley | Stunts |
| Tap Canutt | Stunts |
| Max Balchowsky | Stunts |
| Richard E. Butler | Stunts |
| Bill Couch | Stunt Double |
| Dick Crockett | Stunts |
| May Boss | Stunt Double |
| Carol Daniels | Stunts |
| George DeNormand | Stunts |
| Gary Epper | Stunts |
| Dick Geary | Stunts |
| Stephanie Epper | Stunts |
| Sol Gorss | Stunts |
| Chuck Hayward | Stunts |
| John Indrisano | Stunts |
| John Hudkins | Stunt Double |
| Gil Perkins | Stunts |
| Jack Perkins | Stunts |
| Regis Parton | Stunt Double |
| Wally Rose | Stunts |
| George Robotham | Stunt Double |
| Fred Scheiwiller | Stunts |
| Tom Steele | Stunts |
| Helen Thurston | Stunt Double |
| Jesse Wayne | Stunt Double |
| Dale Van Sickel | Stunt Driver |
| Paul Stader | Stunts |
| Alex Sharp | Stunts |
| Carl Saxe | Stunts |
| Eddie Smith | Stunts |
| Joe Pronto | Stunts |
| Walt La Rue | Stunts |
