 | Ben Stiller als Greg Focker |
 | Robert De Niro als Jack Byrnes |
 | Teri Polo als Pam Byrnes |
 | Blythe Danner als Dina Byrnes |
 | Nicole DeHuff als Debbie Byrnes |
 | Jon Abrahams als Denny Byrnes |
 | Owen Wilson als Kevin Rawley |
 | James Rebhorn als Dr. Larry Banks |
 | Tom McCarthy als Dr. Bob Banks |
 | Phyllis George als Linda Banks |
 | Kali Rocha als Flight Attendant |
 | Bernie Sheredy als Norm the Interrogator |
 | Judah Friedlander als Pharmacy Clerk |
 | Peter Bartlett als Animal Shelter Worker |
 | John Elsen als Chicago Airport Security |
 | Mark Hammer als Hospital Patient |
 | Amy Hohn als Ticket Agent |
| William Severs als Father O'Boyle |
 | John Fiore als Kinky |
| Marilyn Dobrin als Kali Rocha |
| Marci Reid als Traveler |
 | Frank Santorelli als Courier |
 | Russell Hornsby als Late Night Courier |
| Patricia Cook als Little Girl |
| Cody Arens als Little Boy |
 | Cole Hawkins als Little Boy |
 | Spencer Breslin als Little Boy |
| Ina Rosenthal als Wedding Worker |
| Kim Rideout als Nurse |
 | Kresh Novakovic als Airport Policeman |
 | John Joseph Gallagher als Cop |
 | G. A. Aguilar als Cop |
| Lynn Ann Castle als Security Guard |
| Jon Poll | Editor |
| Greg Hayden | Editor |
| John Hamburg | Screenplay |
| Ellen Chenoweth | Casting |
| Jay Roach | Director |
| Jim Herzfeld | Screenplay |
| Peter James | Director of Photography |
| Karin Wiesel | Set Decoration |
| John Kasarda | Art Direction |
| Rusty Smith | Production Design |
| Daniel Orlandi | Costume Supervisor |
| Greg Glienna | Associate Producer |
| Jay Roach | Producer |
| Robert De Niro | Producer |
| Jim Vincent | Associate Producer |
| Jane Rosenthal | Producer |
| Nancy Tenenbaum | Producer |
| Shauna Robertson | Co-Producer |
| Amy Sayres | Co-Producer |
| Randy Newman | Original Music Composer |
| G. A. Aguilar | Stunt Coordinator |
| Randall Poster | Music Supervisor |
| Emo Philips | Associate Producer |
| Steven E. Lawler | Construction Foreman |
| Daniel Geary | Carpenter |
| James Morioka | Assistant Sound Editor |
| David D. Johnson | Visual Effects Supervisor |
| J.C. Brotherhood | Special Effects Coordinator |
| Hyun-joo Kim | Assistant Art Director |
| William Riley | Scenic Artist |
| John Glaser | Assistant Costume Designer |
| Kevin Du Toit | Post Production Assistant |
| Edmund Nardone | Projection |
| Jeff Flach | Location Manager |
| Lenny Vullo | Production Manager |
| Ken Nelson | Construction Coordinator |
| Solange Monnier | Craft Service |
| Joe DeAngelis | Sound Recordist |
| Steven Blaho | Rigging Grip |
| Susie Farris | Casting Associate |
| Julie Arenal | Choreographer |
| Bruno Coon | Music Editor |
| Tod A. Maitland | Sound Mixer |
| George H. Anderson | Supervising Sound Editor |
| Brett Botula | Location Scout |
| Kate Kelly | Production Coordinator |
| Cynthia Bauer | Set Production Assistant |
| Edward O'Donnell | Transportation Captain |
| Bobby Mancuso | First Assistant Camera |
| Victor DeNicola | Hairstylist |
| Lisa Rodgers | Post Production Supervisor |
| Tommy Allen | Property Master |
| Eva Z. Cabrera | Script Supervisor |
| Dennis McNeill | Color Timer |
| Tom Prate | Key Grip |
| Phillip V. Caruso | Still Photographer |
| Rocco Curatolo | Driver |
| Bill Anagnos | Stunts |
| Curtis Croeni | First Assistant Editor |
| Alyson Wellins | Art Department Coordinator |
| Michal Bigger | Makeup Artist |
| Joseph Barry | Stand In |
| Richard Cowan | Assistant Director |
| John Quaglia | Key Hair Stylist |
| Orin Faison | Set Medic |
| Clay Liversidge | Rigging Gaffer |
| Amy Safhay | Greensman |
| Morris Flam | Gaffer |
| Julie Kuehndorf | Publicist |
| Frank Graziadei | Boom Operator |
| Maurice Fitzgerald | Transportation Co-Captain |
| Bill Almeida | Best Boy Electric |
| William MacGhee | Electrician |
| Dennis Drummond | Sound Effects Editor |
| Don Davis | Orchestrator |
| Jonathan Klein | Foley |
| David Davenport | Costumer |
| Joanna Brett | Wardrobe Supervisor |
| Mark Cross | Music Consultant |
| Caesar S. Carnevale | Camera Loader |
| Aleta Shaffer | Art Department Production Assistant |
| Kent Blocher | Assistant Editor |
| Johnny Egan | Production Assistant |
| Steve Ginsburg | Second Assistant Accountant |
| Ronald Burke | Dolly Grip |
| Jeanette Browning | ADR Recordist |
| Judy Pursley | First Assistant Accountant |
| Deanna Leslie | Additional Second Assistant Director |
| Eric Cheripka | Assistant Property Master |
| Renée Tondelli | Supervising ADR Editor |
| Brian Cantaldi | Location Assistant |
| Tamara Bally | Accountant |
| Goro Koyama | Foley Artist |
| Kenny Burke | Best Boy Grip |
| Ralph G. Crowley | Generator Operator |
| Ron Mellegers | Foley Recordist |
| Jim Lillis | Special Effects Technician |
| Carey DePalma | Assistant Location Manager |
| Grant Wilfley | Extras Casting |
| Marco Schnabel | Second Unit Director |
| Susan Silas | Payroll Accountant |
| Amy Lauritsen | Second Assistant Director |
| Mike Bundlie | Graphic Designer |
| Michael Cambria | Second Assistant Camera |
| Gary Burritt | Negative Cutter |
| Brenda Heins | Music Coordinator |
| Juliet D'Annibale | Assistant Production Coordinator |
| David Boulton | ADR Mixer |
| Jennifer Truelove | Second Second Assistant Director |
| Christopher Ferraro | Set Dresser |
| Brian Byers | Other |
| John Davis | Storyboard Artist |
| Valentina Aulisi | Production Secretary |
| Kim Drummond | Dialogue Editor |
| Ron Michaels | Utility Stunts |
| Peter Epstein | Stunts |
| Greg Glienna | Original Film Writer |
| Mary Ruth Clarke | Original Film Writer |
