 | Zac Efron als Dave Stangle |
 | Adam Devine als Mike Stangle |
 | Anna Kendrick als Alice |
 | Aubrey Plaza als Tatiana |
 | Sam Richardson als Eric |
 | Stephen Root als Burt |
 | Sugar Lyn Beard als Jeanie Stangle |
 | Branscombe Richmond als Kalani - BBQ Chef |
 | Marc Maron als Randy |
 | Jake Johnson als Ronnie |
 | Kumail Nanjiani als Keanu |
 | Eugene Cordero als Kai - Hotel Manager |
 | Mary Holland als Becky |
 | Nicole Byer als Office Nicole |
 | Stephanie Allynne als Office Stephanie |
 | Chloe Bridges als Apartment Chloe |
 | Stephanie Faracy als Rosie |
 | Alice Wetterlund als Cousin Terry |
 | Lavell Crawford als Keith |
 | Erik Griffin als Driver |
 | Jake Szymanski als Stable Guy |
 | Wendy Williams als Wendy Williams |
 | Kyle Smigielski als Luke |
| Andrea Miceli als Twin Sister #1 |
| Nancy Miceli als Twin Sister #2 |
| Christina Souza als Call Girl |
 | Olga Kalashnikova als Russian Call Girl |
| Ashley Hobbs als White Supremacist Girl |
| Julia Fae als Grungy Girl #1 |
| Andrea Russett als Grungy Girl #2 |
 | Danielle Zalopany als Militant Girl #1 |
| Tabitha Humphrey als Militant Girl #2 |
| Bob Turton als Bob / Lauralie |
 | Jennie Pierson als Office Jennie |
 | Hilty Bowen als Café Hilty |
 | Tanisha Long als Café Tanisha |
 | Cass Buggé als Apartment Cass |
 | Ayden Mayeri als Apartment Ayden |
 | Liberté Chan als Local Newscaster |
| Sandra Davis als Sandra |
 | Jessika Van als Jessika the Girl in Street |
| Don Pomes als Grandpa Stangle |
| Sally Jackson als Grandma Stangle |
| Rory Hart als Frat Dude |
 | Katherine Klosterman als Anniversary Montage Girl |
| Michael C. Price als Father Mike |
| Paula Fuga als Reception Singer |
| John Cruz als Rough Rider Singer |
| Henry Kapono Ka'aihue als Rough Rider Singer |
| Brother Noland als Rough Rider Singer |
 | Kimee Balmilero als Weird Girl #1 (uncredited) |
| Margo Kazaryan als Pedestrian (uncredited) |
| Jeff Cardoni | Music |
| Jake Szymanski | Director |
| Peter Chernin | Producer |
| Brendan O'Brien | Writer |
| Tara Macken | Stunts |
| Andrew J. Cohen | Executive Producer |
| Nan Morales | Executive Producer |
| Jennifer Euston | Casting |
| Mark Garner | Art Direction |
| Andrew J. Cohen | Writer |
| Tyler B. Robinson | Production Design |
| David Ready | Executive Producer |
| Jonathan Levine | Producer |
| Matthew Clark | Director of Photography |
| Jonathan Schwartz | Editor |
| Katie Doyle | Casting |
| Brendan O'Brien | Executive Producer |
| Jenno Topping | Producer |
| Lee Haxall | Editor |
| Sheila Jaffe | Casting |
| Matthew Wells | Post Production Coordinator |
| John Houlihan | Music Supervisor |
| Debra McGuire | Costume Designer |
| Jon Poll | Additional Editor |
| Caleb Mikler | Assistant Art Director |
| Joelle-Lyn Sarte | Art Department Coordinator |
| Chris Biddle | Set Designer |
| Jeff Errico | Storyboard Artist |
| Chuck Potter | Set Decoration |
| Christopher J. Wood | Leadman |
| Julie DeRose | Set Decorating Coordinator |
| Sam Sternthall | Set Dresser |
| Mathias Van Wessinger | Set Dresser |
| Sean Hallock | Set Dresser |
| Jody Miller | "A" Camera Operator |
| Tony Nagy | First Assistant "A" Camera |
| Rylan Akama | Second Assistant "A" Camera |
| Steve Adcock | "B" Camera Operator |
| Matthew Berner | First Assistant "B" Camera |
| Caleb Lucero | Second Assistant "B" Camera |
| Michael Romano | Digital Imaging Technician |
| Gemma La Mana | Still Photographer |
| M. Ryan Traylor | Second Second Assistant Director |
| Brenda Lopez | Script Supervisor |
| Lily Gwyer-Miller | Post Production Supervisor |
| Chris Talson | First Assistant Editor |
| Ryan C. Fill | Assistant Editor |
| Terry Wilson | Music Editor |
| Donald Sylvester | Supervising Sound Editor |
| Teri E. Dorman | Supervising Dialogue Editor |
| Doug Jackson | Sound Effects Editor |
| Smokey Cloud | First Assistant Sound Editor |
| R.J. Kizer | ADR Editor |
| Laura Graham | ADR Editor |
| David Wolowic | Assistant Sound Editor |
| James Bolt | Sound Re-Recording Mixer |
| Andy King | Sound Re-Recording Mixer |
| Willie D. Burton | Production Sound Mixer |
| Douglas Shamburger | Boom Operator |
| James Crawford | Gaffer |
| Stephen Bacquet | Best Boy Electric |
| Don Tomich | Rigging Gaffer |
| Michael C. Price | Key Grip |
| Kevin Kersting | Best Boy Grip |
| James D. Wickman | Dolly Grip |
| Don Chong | Dolly Grip |
| Tuiaana Scanlan | Grip |
| Keala Nakanelua | Rigging Grip |
| Deborah Myles Davis | Costume Supervisor |
| Megan Wiser | Key Costumer |
| Charles W. Kaeo | Key Costumer |
| Sheryl Smyres | Set Costumer |
| Cory Ching | Set Costumer |
| Dallas D. Dornan | Costumer |
| Steven Stitt-Bergh | Costumer |
| Linda Vollert | Costumer |
| Aaron Ellis | Costumer |
| Maryann Dearmore | Costumer |
| Jayoung Yoon | Costumer |
| Judith Y. Matsumoto | Seamstress |
| Michael Tereschuk | Tailor |
| Whitney James | Makeup Department Head |
| Desne J. Holland | Makeup Department Head |
| Claudia Pascual | Makeup Artist |
| Karen Iboshi Preiser | Makeup Artist |
| Laine Rykes | Makeup Artist |
| Janine Rath-Thompson | Hair Department Head |
| Michelle Diamantides | Key Hair Stylist |
| Karen Bartek | Hairstylist |
| Katy Yung | Hairstylist |
| John Panzarella | Location Manager |
| Leslie Thorson | Assistant Location Manager |
| Ryan Hoke | Assistant Location Manager |
| Travis Logan | Assistant Location Manager |
| Malia Hulleman | Assistant Location Manager |
| Pono Guerrero | Location Assistant |
| Joshua A. Smith | Location Assistant |
| Logan Wilkin | Location Assistant |
| Gay Perello | Property Master |
| Julie Witherington | Assistant Property Master |
| Nalu Carvalho | Props |
| Michelle Olivia Seamon | Casting Associate |
| Jennifer Presser | Casting Associate |
| Jennifer Yoo | Casting Associate |
| Emer O'Callaghan | Casting Associate |
| Katie Doyle | Extras Casting |
| Eric Bylander | Special Effects Coordinator |
| Guy Belegaud | Construction Coordinator |
| Matthew Leong | Greensman |
| Zoila Gomez | Production Coordinator |
| Portia Fontes | Assistant Production Coordinator |
| Amanda Finn | Assistant Production Coordinator |
| Susannah Brengel | Production Accountant |
| Sean Carville | First Assistant Accountant |
| Kimberly Choi | Assistant Accountant |
| Nicole Nakamoto | Assistant Accountant |
| Lori M. Roberts | Payroll Accountant |
| Sue Chipperton | Animal Coordinator |
| Jamal Sims | Choreographer |
| Michael Umble | Unit Publicist |
| Dayne Ahuna | Craft Service |
| John Reed | Transportation Coordinator |
| Leroy Reed | Transportation Captain |
| Richard Groder | Transportation Captain |
| Greg Lomasney | Assistant Editor |
| Jesse Johnstone | Sound Recordist |
| Brian Bair | Sound Engineer |
| Charleen Richards-Steeves | ADR Mixer |
| David Betancourt | ADR Mixer |
| David Lucarelli | ADR Recordist |
| Christine Sirois | ADR Recordist |
| Derek Casari | ADR Recording Engineer |
| Goro Koyama | Foley Artist |
| Andy Malcolm | Foley Artist |
| Sandra Fox | Foley Artist |
| Don White | Foley Mixer |
| Jack Heeren | Foley Mixer |
| Kevin Schultz | Foley Mixer |
| Gary Hymes | Second Unit Director |
| Lynn K. D'Angona | Second Unit First Assistant Director |
| Peter Lyons Collister | Second Unit Director of Photography |
| Stephen Coleman | Orchestrator |
| Laura Albert | Stunts |
