 | Dustin Hoffman als Sam Daniels |
 | Rene Russo als Robby Keough |
 | Morgan Freeman als General Billy Ford |
 | Kevin Spacey als Casey Schuler |
 | Cuba Gooding Jr. als Major Salt |
 | Donald Sutherland als General Donald McClintock |
 | Patrick Dempsey als Jimbo Scott |
 | Zakes Mokae als Dr. Benjamin Iwabi |
 | Malick Bowens als Dr. Raswani |
 | Susan Lee Hoffman als Dr. Lisa Aronson |
 | Benito Martinez als Dr. Julio Ruiz |
 | Bruce Jarchow als Dr. Mascelli |
 | Leland Hayward III als Henry Seward |
| Daniel Chodos als Rudy Alvarez |
 | Dale Dye als Colonel Briggs |
 | Kara Keough als Kate Jeffries |
 | Gina Menza als Mrs. Jeffries |
| Per Didrik Fasmer als Mr. Jeffries |
 | Michelle Joyner als Sherry Mauldin |
| Donald Forrest als Mack Mauldin |
| Julie Pierce als Erica Mauldin |
 | Tim Ransom als Tommy Hull |
| Michelle M. Miller als Darla Hull |
 | Maury Sterling als Sandman One |
 | Michael Emanuel als Sandman One Co-Pilot |
 | Lucas Dudley als Viper One Pilot |
| Robert Alan Joseph als Viper Two Pilot |
 | Joseph Latimore als Viper Two Co-Pilot |
 | Michael Sottile als Gunner Pilot |
| Ed Beechner als Gunner |
| Matthew Saks als Sergeant Wolf |
 | Diana Bellamy als Mrs. Pananides |
 | Lance Kerwin als American Mercenary |
| Brett Oliver als Belgian Mercenary |
| Eric Mungai Nguku als African Nurse |
| Larry Hine als Young McClintock |
| Nickolas H. Marshall als Young Ford |
| Douglas Hebron als Ju-Ju Man |
| Jae Woo Lee als Korean Captain |
| Johnny Kim als Seaman Chulso Lee |
 | Bill Stevenson als Biotest Guard |
 | Kellie Overbey als Alice |
| Dana Andersen als Corinne |
 | Patricia Place als Mrs. Foote |
 | Nicholas Pappone als Little Boy on Plane |
| Traci Odom als Little Boy's Mother |
 | Herbert Jefferson Jr. als Boston Doctor #1 |
 | Thomas Crawford als Boston Doctor #2 |
| Buzz Barbee als Boston Doctor #3 |
 | Jenna Byrne als Tracy |
 | Brian Reddy als Tracy's Father |
 | Ina Romeo als Mrs. Logan |
| Teresa Velarde als Nurse Emma |
 | Jane Jenkins als Nurse Jane |
| Carmela Rappazzo als Hospital Receptionist |
 | Kurt A. Boesen als Mayor Gaddis |
 | Jack Rader als Police Chief Fowler |
| Robert Rigamonti als Country Health Official |
| Mimi Doyka als Frightened Mother |
| C. Jack Robinson als Biotest Manager |
 | Robert Alan Beuth als George Armistead |
 | Gordon Michaels als Man in Line |
 | Peter Looney als White House Counsel |
 | Conrad Bachmann als California Governor |
| Cary J. Pitts als Anchorman |
| Cynthia Harrison als Co-Anchor |
| Marcus Hennessy als Station Manager |
| Albert Owens als Broadcast Director |
| David Silverbrand als TV Reporter |
 | Julie Araskog als Janet Adams |
| Frank Rositani als Senator Rosales |
 | George Christy als Senator |
| Bruce Isacson als Jaffe |
| Marilyn Brandt als Ford's Secretary |
| Philip Handy als Sergeant Meyer |
| Tim Frazee als MP #1 |
| Moses Williams als MP #2 |
| Roland Tsui als MP #3 |
| Keith Butler als MP #4 |
| Davi Lee Phillips als MP #5 |
| Ralph Miller als Officer #1 |
 | Mark Brown als Officer #2 |
 | Jim Antonio als Dr. Drew Reynolds |
| Ellsworth Hanna als Sailor at Cocktail Party (uncredited) |
| Jeanne Hanna als Sailor's Wife at Cocktail Party (uncredited) |
 | Bruce Holman als Aide to White House Chief-of-Staff (uncredited) |
 | Jack Kyle als Doctor (uncredited) |
| Bob Lazar als General (uncredited) |
 | John Lizzi als Newsroom Reporter (uncredited) |
 | Beau Lotterman als Army Major (uncredited) |
 | David Novak als Diplomat (uncredited) |
 | Ross Turner als Townsperson (uncredited) |
 | J.T. Walsh als Chief of Staff (uncredited) |
 | David A.R. White als Army Pilot (uncredited) |
| Robert 'Bobby Z' Zajonc als Army Pilot (uncredited) |
| Lynzee Klingman | Editor |
| Anne Kopelson | Executive Producer |
| James Newton Howard | Original Music Composer |
| William Sandell | Production Design |
| Neil Travis | Editor |
| Laurence Dworet | Screenplay |
| Wolfgang Petersen | Director |
| Robert Roy Pool | Screenplay |
| Arnold Kopelson | Producer |
| Duncan Henderson | Executive Producer |
| Wolfgang Petersen | Producer |
| William Hoy | Editor |
| Michael Ballhaus | Director of Photography |
| Michael C. Mason | Music Score Producer |
| Tom West | Best Boy Grip |
| Jane Jenkins | Casting |
| Nancy Patton | Art Direction |
| Rosemary Brandenburg | Set Decoration |
| June Westmore | Makeup Artist |
| Gail Katz | Producer |
| Erica Edell Phillips | Costume Design |
| Kathy W. Estocin | Hairstylist |
| Ellis Burman Jr. | Makeup Artist |
| Susan A. Cabral | Key Makeup Artist |
| Virginia G. Hadfield | Key Hair Stylist |
| Diane Pepper | Hairstylist |
| Stephen Joel Brown | Co-Producer |
| Nana Greenwald | Co-Producer |
| Janet Hirshenson | Casting |
| Flo Avery | Hairstylist |
| Sanford Panitch | Co-Producer |
| Francis J. Pezza | Art Direction |
| Vivian McAteer | Hairstylist |
| Stephen E. Rivkin | Editor |
| Monty Westmore | Makeup Artist |
| Wylie Stateman | Supervising Sound Editor |
| Gregg Baxter | Supervising Sound Editor |
| Peter Kohn | First Assistant Director |
| Dennis E. Jones | Production Manager |
| John Rusk | Second Assistant Director |
| Buddy Van Horn | Stunt Coordinator |
| Keith Tellez | Stunt Coordinator |
| Richard L. Blackwell | Stunts |
| Robby Robinson | Stunts |
| Shane Dixon | Stunts |
| Michael Runyard | Stunts |
| Charlie Brewer | Stunts |
| Edward T. McAvoy | Assistant Art Director |
| Carl J. Stensel | Set Designer |
| Stella Vaccaro | Set Designer |
| Tom Reta | Set Designer |
| Eric W. Orbom | Set Designer |
| Dianne Dreyer | Script Supervisor |
| Carl Aldana | Production Illustrator |
| Florian Ballhaus | "A" Camera Operator |
| Mark Emery Moore | "B" Camera Operator |
| Mark Emery Moore | Steadicam Operator |
| Mikael Glattes | First Assistant "A" Camera |
| Gary Dunham | First Assistant "B" Camera |
| Peter Sorel | Still Photographer |
| Jeffrey Thorin | Second Assistant Camera |
| Michael Martinez | Second Assistant Camera |
| Amy Hergoth | Second Assistant Camera |
| James R. Tynes | Chief Lighting Technician |
| John 'Fest' Sandau | Assistant Chief Lighting Technician |
| Stanley L. Gonsales | Assistant Chief Lighting Technician |
| Charlie McIntyre | Rigging Gaffer |
| J. Patrick Daily | Key Grip |
| Rex Hiscocks | Best Boy Grip |
| Kent H. Jorgensen | Dolly Grip |
| Eric Whitehead | Dolly Grip |
| Delia Circelli | Production Office Coordinator |
| C.C. Barnes | Second Second Assistant Director |
| Rob Harris | Unit Publicist |
| Richard Lightstone | Production Sound Mixer |
| Gabriel Cubos | Boom Operator |
| William G. Flick | Cableman |
| John Frazier | Special Effects Supervisor |
| Mark Vargo | Visual Effects Supervisor |
| Russell Bobbitt | Property Master |
| Tom Numbers | Costume Supervisor |
| Linda Serijan | Costume Supervisor |
| Cal DiValerio | Construction Coordinator |
| Jim Weidman | Music Editor |
| Donald O. Mitchell | Sound Re-Recording Mixer |
| John T. Reitz | Sound Re-Recording Mixer |
| Michael Herbick | Sound Re-Recording Mixer |
| David E. Campbell | Sound Re-Recording Mixer |
| Frank A. Montaño | Sound Re-Recording Mixer |
| Gregg Rudloff | Sound Re-Recording Mixer |
| Artie Kane | Conductor |
| Todd Egan | Assistant Sound Editor |
| David Stanke | Assistant Sound Editor |
| Rickley W. Dumm | Assistant Sound Editor |
| John Rice | Assistant Sound Editor |
| Tim Groseclose | Assistant Sound Editor |
| Thomas O'Neil Younkman | Assistant Sound Editor |
| Robert Batha | First Assistant Sound Editor |
| Doc Kane | ADR Mixer |
| Thomas J. O'Connell | ADR Mixer |
| Gary A. Hecker | Foley Artist |
| Dan O'Connell | Foley Artist |
| James Ashwill | Foley Artist |
| Nerses Gezalyan | Foley Artist |
| Bill Voigtlander | ADR Editor |
| Laura Graham | ADR Editor |
| Holly Huckins | ADR Editor |
| Petra Bach | ADR Editor |
| Andrew London | ADR Editor |
| Craig S. Jaeger | Foley Editor |
| Hector C. Gika | Foley Editor |
| Bob Beher | Foley Editor |
| Lou Kleinman | Foley Editor |
| Clayton Collins | Dialogue Editor |
| Patrick J. Foley | Dialogue Editor |
| Michael P. Cook | Dialogue Editor |
| Chris Hogan | Dialogue Editor |
| Sarah Goldsmith | Dialogue Editor |
| Dan M. Rich | Dialogue Editor |
| Bruce Richardson | Supervising Sound Effects Editor |
| Scott Martin Gershin | Sound Effects Editor |
| Paul Timothy Carden | Sound Effects Editor |
| Dino DiMuro | Sound Effects Editor |
| Peter Michael Sullivan | Sound Effects Editor |
| Alan Rankin | Sound Effects Editor |
| Dan Hegeman | Sound Effects Editor |
| Jay B. Richardson | Sound Effects Editor |
| Randy Kelley | Sound Effects Editor |
| Glenn T. Morgan | Sound Effects Editor |
| Peter J. Lehman | Sound Effects Editor |
| Brian McPherson | Sound Effects Editor |
| Michael D. Wilhoit | Sound Effects Editor |
| Larry Kemp | Sound Effects Editor |
| Eric Chambers | Stunts |
| David Lowery | Production Illustrator |
| Linda Antipala | Casting |
| Judith Bouley | Location Casting |
| Randi Hiller | Casting Assistant |
| Jimmy Jue | Extras Casting |
| Keith Tellez | Stunt Double |
| Steve Kelso | Stunt Double |
| Steve Kelso | Stunt Driver |
| Lynn Salvatori | Stunt Double |
| Maria Norman | Executive Assistant |
