 | Randy Quaid als Nick Laemle |
 | Mary Beth Hurt als Lily Laemle |
 | Sandy Dennis als Millie Dew |
 | Bryan Madorsky als Michael Laemle |
| Juno Mills-Cockell als Sheila Zellner |
 | Kathryn Grody als Miss Judith Baxter |
 | Deborah Rush als Mrs. Gladys Zellner |
 | Graham Jarvis als Mr. Marty Zellner |
| Helen Carscallen als Grandmother |
| Warren Van Evera als Grandfather |
 | Wayne Robson als Lab Attendant |
| Uriel Byfield als Little boy |
| Mariah Balaban als Little girl |
| Larry Palef als Announcer |
| Bob Balaban | Director |
| Christopher Hawthorne | Writer |
| Andris Hausmanis | Art Direction |
| Bonnie Palef | Producer |
| Mitchell Cannold | Executive Producer |
| Steven Reuther | Executive Producer |
| Billy Hopkins | Casting |
| Mike Harris | Set Decoration |
| Arthur Rowsell | Costume Design |
| Ernest Day | Director of Photography |
| Robin Vidgeon | Director of Photography |
| Bill Pankow | Editor |
| Risa Bramon Garcia | Casting |
| Jonathan Elias | Original Music Composer |
| Skip Lievsay | Supervising Sound Editor |
| Angelo Badalamenti | Original Music Composer |
| Linda Gill | Makeup Artist |
| Suzanne Lore | Production Manager |
| Dori Berinstein | Production Executive |
| Andrew Poulos | Assistant Art Director |
| Laura Civiello | Sound Editor |
| Rick Dior | Sound Re-Recording Mixer |
| Neil L. Kaufman | Sound Editor |
| Eliza Paley | Sound Editor |
| Gail Showalter | Sound Editor |
| Philip Stockton | Sound Editor |
| Brian Eddolls | Sound Designer |
| Brian Eddolls | Sound Editor |
| Harry Peck Bolles | Sound Editor |
