 | Rosie Perez als Perdita Durango |
 | Javier Bardem als Romeo Dolorosa |
 | Harley Cross als Duane |
 | Aimee Graham als Estelle |
 | James Gandolfini als Willie 'Woody' Dumas |
 | Screamin' Jay Hawkins als Adolfo |
 | Carlos Bardem als Reggie San Pedro |
 | Santiago Segura als Shorty Dee |
 | Demián Bichir als Catalina |
 | Alex Cox als Doyle |
 | Harry Porter als Ford |
| Carlos Arau als Phillips |
 | Don Stroud als Santos |
 | Regina Orozco als Lilly |
 | Roger Cudney als Herbert |
| Erika Carlsson als Glory Ann |
 | Marco Bacuzzi als Tony |
 | Josefina Echánove als Romeo's Grandmother |
 | Miguel Galván als Doug |
| Paul Dapra als Policeman #1 |
 | Craig Vincent als Policeman #2 |
| Jessie Faller als Bank Teller |
 | Katie Barberi als Stewardess |
| Álex de la Iglesia | Director |
| Barry Gifford | Screenplay |
| David Trueba | Screenplay |
| Andrés Vicente Gómez | Producer |
| Simon Boswell | Original Music Composer |
| Flavio Martínez Labiano | Director of Photography |
| Teresa Font | Editor |
| Álex de la Iglesia | Writer |
| Jorge Guerricaechevarría | Writer |
| Pablo Barbachano | Executive Producer |
| Fernando Bovaira | Executive Producer |
| Marco Gómez | Associate Producer |
| Miguel Necoechea | Executive Producer |
| Max Rosenberg | Executive Producer |
| Nicole Arbusto | Casting |
| Joy Dickson | Casting |
| Gabe Ibáñez | Animation |
| José Luis Arrizabalaga | Production Design |
| Biaffra | Production Design |
| Andrew Bernard | Art Direction |
| Salvador Parra | Art Direction |
| Ana Solares | Art Direction |
| Helen Britten | Set Decoration |
| Claudio Contreras | Set Decoration |
| María Estela Fernández | Costume Design |
| Glenn Ralston | Costume Design |
| Zaida Monteforte | Art Department Coordinator |
| Star Fields | Construction Coordinator |
| Bill Garber | Greensman |
| Gary W. Shaw | Key Grip |
| Mansur Johnson | Grip |
| Carlos Cabeceràn | Steadicam Operator |
| Drew Carolan | Still Photographer |
| Gabriela Fernández | Assistant Costume Designer |
| Mercedes Guillot | Makeup Artist |
| Larry D. Koszakovszky | Set Dressing Artist |
| Jason LaFountain | Driver |
| Brenton L. Lane | Property Master |
| Joel S. Griffith | Scenic Artist |
| Todd Seashore | Security |
| Jennifer Scott | Stand In |
| Julian Bucio | Stunt Coordinator |
| Oscar Carles | Stunts |
| Robert Brubaker | Transportation Captain |
| David Carlton White | Transportation Co-Captain |
| Anne McCaffrey | Unit Production Manager |
| Charlie Carpenter | Utility Stunts |
| Tod Swindell | First Assistant Director |
| Beatriz de Anda | Script Supervisor |
| Dean Anthony | Electrician |
| Gary A. Kilgore | Rigging Grip |
| Laura Alemán | Location Manager |
| Marc Bèdia | Production Coordinator |
| José Luis Escolar | Production Manager |
| León Sandoval | Boom Operator |
| Terry Davies | Orchestrator |
| Ray Gillon | Sound Designer |
| Santiago Thévenet | Sound Editor |
| Jackson Burns | Special Effects Supervisor |
| Tim Sassoon | Visual Effects |
| Jim Wheelock | Visual Effects Supervisor |
| Jaume Puig | Dolby Consultant |
| Martín Torres | Unit Manager |
| Adela Cortázar | Costume Assistant |
| José Luis Escolar | Assistant Director |
| Adrian Grünberg | Second Second Assistant Director |
| Mark Brooks | Third Assistant Director |
| Greg Finnin | Assistant Property Master |
| Salvador de la Fuente | Location Sound Mixer |
| Jackson Burns | Stunt Double |
| Mark Brooks | Stunt Driver |
| Steven J. Winslow | Assistant Camera |
| Kenny Christiansen | Best Boy Grip |
| Gloria Avila | Camera Trainee |
| Steven Aquilino | Second Assistant Camera |
| Alejandro Lázaro | Assistant Editor |
| José María Bello | Post Production Coordinator |
| Terry Davies | Conductor |
| Adam Gomez | Production Assistant |
