 | Johnny Depp als Jack Sparrow |
 | Orlando Bloom als Will Turner |
 | Keira Knightley als Elizabeth Swann |
 | Geoffrey Rush als Hector Barbossa |
 | Stellan Skarsgård als William "Bootstrap Bill" Turner |
 | Chow Yun-fat als Sao Feng |
 | Bill Nighy als Davy Jones |
 | Jack Davenport als James Norrington |
 | Kevin McNally als Joshamee Gibbs |
 | Tom Hollander als Cutler Beckett |
 | Naomie Harris als Tia Dalma |
 | Jonathan Pryce als Weatherby Swann |
 | Keith Richards als Teague Sparrow |
 | Lee Arenberg als Pintel |
 | Mackenzie Crook als Ragetti |
 | Greg Ellis als Theodore Groves |
 | David Bailie als Cotton |
 | Martin Klebba als Marty |
 | David Schofield als Ian Mercer |
 | Lauren Maher als Scarlett |
 | Vanessa Branch als Giselle |
 | Angus Barnett als Mullroy |
 | Giles New als Murtogg |
 | Reggie Lee als Tai Huang |
 | Dominic Scott Kay als Henry Turner |
 | Takayo Fischer als Ching |
 | David Meunier als Greitzer |
 | Ho-Kwan Tse als Hadras |
 | Andy Beckwith als Clacker |
 | Peter Donald Badalamenti II als Penrod |
 | Christopher S. Capp als Cotton's Parrot (voice) |
 | Hakeem Kae-Kazim als Jocard |
 | Ghassan Massoud als Ammand |
 | Omid Djalili als Aksay / Pusasn |
 | Michelle Lee als Lian |
| Huynh Quang als Pirate |
 | Ned Wertimer als Singing Gallows Pirate |
 | Arnold Chon als Asian Pirate (uncredited) |
 | Larry Leong als Steng |
| Craig Wood | Editor |
| Eric McLeod | Producer |
| Priscilla John | Casting |
| Terry Rossio | Screenplay |
| Peter Kohn | Producer |
| Cheryl Carasik | Set Decoration |
| Denise Chamian | Casting |
| Penny Rose | Costume Design |
| Jerry Bruckheimer | Producer |
| Gore Verbinski | Director |
| Mike Stenson | Executive Producer |
| Hans Zimmer | Original Music Composer |
| Stephen E. Rivkin | Editor |
| Liz Dann | Costume Design |
| Ve Neill | Makeup Department Head |
| Pat Sandston | Producer |
| Ted Elliott | Screenplay |
| Rick Heinrichs | Production Design |
| Dariusz Wolski | Director of Photography |
| John Dexter | Art Direction |
| Chad Oman | Producer |
| James Ward Byrkit | Conceptual Design |
| Melissa Muik | Music Editor |
| Barbara McDermott | Music Editor |
| Sharron Reynolds-Enriquez | Script Supervisor |
| Bob Badami | Music Supervisor |
| Pamela Alch | Script Supervisor |
| Katie Greathouse | Music Editor |
| Karen Golden | Script Supervisor |
| John Dixon | Stunts |
| Allen Hall | Special Effects Coordinator |
| Dottie Starling | CGI Supervisor |
| Charles Gibson | Visual Effects |
| Sala Baker | Stunts |
| Donald Dowd | Production Director |
| Robert Edwards | ADR Recordist |
| Geoff Campbell | Character Modelling Supervisor |
| Richard Alonzo | Makeup Artist |
| Leslie Devlin | Facial Setup Artist |
| Ken Diaz | Makeup Supervisor |
| William Ladd Skinner | Art Direction |
| Pat Sandston | Associate Producer |
| Gabriel De Cunto | Makeup Artist |
| Leslie Devlin | Makeup Artist |
| Ted Elliott | Characters |
| Stuart Beattie | Characters |
| Bruce Crone | Art Direction |
| John Dexter | Supervising Art Director |
| Steve Buscaino | Prosthetics |
| Ken Diaz | Tattoo Designer |
| Jay Wolpert | Characters |
| Brigham Taylor | Production Executive |
| Steven E. Anderson | Makeup Artist |
| Robin Beauchesne | Makeup Artist |
| Monique DeSart | Hairstylist |
| Terry Rossio | Characters |
| William Hawkins | Art Direction |
| Kris Evans | Makeup Artist |
| Elena Arroy | Makeup Artist |
| Hazel Catmull | Hairstylist |
| Jed Dornoff | Makeup & Hair Assistant |
| Roxanne Ferguson | Hairstylist |
| Bruce Hendricks | Executive Producer |
| Jack Kney | Producer |
| Belinda Bryant | Makeup Artist |
| Gloria Pasqua Casny | Key Hair Stylist |
| David Dupuis | Makeup Artist |
| Catherine Childers | Hairstylist |
| Eric McLeod | Executive Producer |
| Barbara Cantu | Hairstylist |
| Chad Oman | Executive Producer |
| Natasha Allegro | Hairstylist |
| Peter Kohn | Associate Producer |
| John Frazier | Special Effects Supervisor |
| Martin Samuel | Hair Designer |
| John Knoll | Visual Effects Supervisor |
| Hal Hickel | Animation Supervisor |
| Armen Ksajikian | Musician |
| Thomas Rosales Jr. | Stunts |
| Mark De Alessandro | Stunts |
| Denney Pierce | Stunts |
| Terry Rossio | Lyricist |
| Justin Pollard | Researcher |
| Dane Farwell | Stunts |
| Joey Anaya | Stunts |
| Noby Arden | Stunts |
| Tsuyoshi Abe | Stunts |
| Dan Brown | Stunts |
| Richard L. Blackwell | Stunts |
| Joe Bucaro III | Stunts |
| Keith Campbell | Stunts |
| Jay Caputo | Stunts |
| Richard Bucher | Stunts |
| Darryl Chan | Stunts |
| Alex Chansky | Stunts |
| Sebastiano Cartier | Stunts |
| Tony Angelotti | Stunt Double |
| Greg Anthony | Stunts |
| Fernando Chien | Utility Stunts |
| Kevin Abercrombie | Utility Stunts |
| Phil Culotta | Stunts |
| Augie Davis | Stunts |
| Shawn Crowder | Utility Stunts |
| J. Mark Donaldson | Stunts |
| Geo Corvera | Stunts |
| Brian Collins | Stunts |
| Brycen Counts | Stunts |
| Ilram Choi | Stunts |
| Arnold Chon | Stunts |
| Brian Duffy | Stunts |
| Philip Tan | Stunts |
| Marty Murray | Stunts |
| Don Theerathada | Stunts |
| Kurt D. Lott | Stunts |
| Samuel Le | Stunts |
| James Lew | Stunts |
| Theo Kypri | Stunt Double |
| Danny Le Boyer | Stunts |
| Anthony Kramme | Stunts |
| Keii Johnston | Utility Stunts |
| Reuben Langdon | Stunts |
| Randall Huber | Stunts |
| Lisa Hoyle | Stunts |
| Zach Hudson | Stunts |
| Sam Hargrave | Utility Stunts |
| Ben Hernandez Bray | Stunts |
| John Koyama | Stunts |
| Steven Ho | Stunts |
| Dean Grimes | Utility Stunts |
| Charles Grisham | Stunts |
| Al Goto | Stunts |
| Erica Grace | Stunt Double |
| Richie Gaona | Stunts |
| Jeremy Fry | Stunts |
| Mickey Giacomazzi | Stunts |
| Jonathan Eusebio | Stunts |
| J. Armin Garza II | Stunt Driver |
| Greg Wayne Elam | Stunts |
| Darin Fujimori | Stunts |
| Paul Eliopoulos | Stunts |
| Jayson Dumenigo | Stunts |
| Will Leong | Utility Stunts |
| Michelle Lee | Stunts |
| Christopher Leps | Stunts |
| Sam Looc | Utility Stunts |
| Kirk Maxwell | Stunt Double |
| Rob Mars | Stunt Double |
| Angela Meryl | Stunt Double |
| Norman Mora | Stunts |
| Tom Morga | Stunts |
| Ray Lykins | Stunt Double |
| Casey O'Neill | Stunts |
| Hugh Aodh O'Brien | Utility Stunts |
| J.P. Romano | Stunts |
| Víctor Quintero | Stunts |
| Norb Phillips | Stunts |
| Marc Schaffer | Stunt Double |
| Gregg Sargeant | Stunt Double |
| Jim Palmer | Stunts |
| Mark Norby | Stunts |
| Jim Stephan | Stunts |
| Lewis Tan | Stunts |
| Trampas Thompson | Stunts |
| Jen Sung | Stunts |
| Steve Tartalia | Stunts |
| Aaron Toney | Stunts |
| Russell Towery | Stunt Double |
| Steve Upton | Stunts |
| Jon Valera | Stunts |
| Mark Vanselow | Stunts |
| Jack West | Stunt Double |
| Ryan Watson | Stunts |
| Webster Whinery | Utility Stunts |
| Webster P. Whinery Jr. | Stunts |
| Jeff Wolfe | Stunts |
| Marcus Young | Stunts |
| Kofi Yiadom | Stunts |
| David Wald | Stunts |
| Jesse James Youngblood | Stunts |
| Lincoln Simonds | Stunts |
| Buddy Sosthand | Stunt Double |
| Mark McDaniels | Stunts |
| Michael Li | Stunts |
| Martin Klebba | Stunt Double |
| Azmyth Kaminski | Stunts |
| George Marshall Ruge | Stunt Coordinator |
| George Marshall Ruge | Second Unit Director |
| Charles Gibson | Second Unit Director |
| Amy Schmidt | Second Assistant Director |
| David H. Venghaus Jr. | First Assistant Director |
| Steven F. Beaupre | Second Second Assistant Director |
| Jeffrey Schwartz | Second Second Assistant Director |
| Johnny Sullivan | Stunts |
| Lou Pecora | Compositing Supervisor |
| Addison Teague | Sound Effects Editor |
