 | Johnny Depp als Jack Sparrow |
 | Javier Bardem als Armando Salazar |
 | Geoffrey Rush als Hector Barbossa |
 | Brenton Thwaites als Henry Turner |
 | Kaya Scodelario als Carina Smyth |
 | Kevin McNally als Joshamee Gibbs |
 | Golshifteh Farahani als Shansa |
 | David Wenham als Scarfield |
 | Stephen Graham als Scrum |
 | Angus Barnett als Mullroy |
 | Martin Klebba als Marty |
 | Adam Brown als Cremble |
 | Giles New als Murtogg |
 | Orlando Bloom als Will Turner |
 | Keira Knightley als Elizabeth Swann |
 | Paul McCartney als Uncle Jack |
 | Delroy Atkinson als Pike |
 | Danny Kirrane als Bollard |
 | Juan Carlos Vellido als Lieutenant Lesaro |
 | Rodney Afif als Officer Madga |
 | Rupert Raineri als Officer Santos |
 | Stephen Lopez als Officer Moss |
 | Nico Cortez als Spanish Officer |
 | Mahesh Jadu als Spanish Soldier |
 | Bruce Spence als Mayor Dix |
 | Justin Smith als Mr. Krill |
 | John Leary als Mr. Swift |
 | Anthony De La Torre als Young Jack Sparrow |
 | Finn Ireland als Young Pirate Jeff |
 | James Mackay als Maddox |
 | Bryan Probets als Bowen |
 | Will Ward als Pirate in Flashback |
 | Lewis McGowan als Young Henry Turner |
 | Alexander Scheer als Young Captain Teague |
 | Richard Piper als Captain Toms |
 | Michael Dorman als First Officer Wade |
 | Rohan Nichol als Officer Cole |
 | Paul Armstrong als Old Pirate |
 | Robert Morgan als Grimes |
| Andreas Sobik als Pirate Captain |
 | Goran D. Kleut als Pirate with Broom |
 | Scott G. Anderson als British Officer |
 | Travis Jeffery als British Soldier |
| Andrew Fraser als British Soldier |
 | Akos Armont als British Soldier |
 | Sean Lynch als British Soldier |
 | Ben O'Toole als British Soldier |
| Dakota Askew als Young Monarch Soldier |
 | Jamie Carter als Young Monarch Soldier |
 | Joe Klocek als Young Monarch Soldier |
 | Derani Scarr als Woman |
 | Zoe Ventoura als Mayor's Wife |
| Lenny Firth als Fisherman |
 | Akshay Caplash als CG Ghost Soldier |
| Jordan Fulleylove als CG Ghost Soldier |
 | Mivon Prince-Leyva als CG Ghost Soldier |
 | Rafael Torrijos als CG Ghost Soldier |
 | James Fraser als Young Greenhorn |
 | Kenneth Radley als Pig Kelly |
 | Hannah Walters als Beatrice |
 | Jonathan Elsom als Priest |
 | K. Todd Freeman als Captain Morgan |
| Matthew Walker als Confessional Priest |
 | Darcy Laurie als Uncle Jack's Cellmate |
 | James Lawson als Jail Guard |
 | Brooke Chamberlain als Upper Class Lady (uncredited) |
 | Jessica Green als Townswoman (uncredited) |
 | Kiara Freeman als Townschild (uncredited) |
 | Piper Nairn als Townschild (uncredited) |
 | Suzanne Dervish-Ali als Townsperson (uncredited) |
 | Donnie Baxter als Townsperson (uncredited) |
 | Winnie Mzembe als Maid (uncredited) |
 | Christie-Lee Britten als Greenwich Village Upper Class Lady (uncredited) |
 | Mollie McGregor als Twin Middle Class Lady (uncredited) |
 | Sophia McGregor als Twin Middle Class Lady (uncredited) |
 | Garreth Hadfield als Ghost Soldier / Red Coat Soldier (uncredited) |
| Mike Beaulieu | Animation Supervisor |
| Axel Akesson | CG Supervisor |
| Richard Clegg | CG Supervisor |
| Zameer Hussain | 2D Supervisor |
| Robert Bock | VFX Director of Photography |
| Luke Dhand | VFX Editor |
| Leah Jones | VFX Editor |
| Wes Walcott | VFX Editor |
| Yogesh Chautel | VFX Production Coordinator |
| Cliff Welsh | VFX Supervisor |
| Mark Carr | Visual Effects Editor |
| George McCarthy | Visual Effects Editor |
| Céline Zapater | Visual Effects Editor |
| Jack Runyon | Visual Effects Editor |
| Hero Chev | Visual Effects Editor |
| Jeff Nathanson | Screenplay |
| Terry Rossio | Characters |
| Jerry Bruckheimer | Producer |
| Joachim Rønning | Director |
| Espen Sandberg | Director |
| Seth Engstrom | Conceptual Design |
| Martin Lipmann | Visual Effects Supervisor |
| Roger Barton | Editor |
| Leigh Folsom Boyd | Editor |
| Jeff Nathanson | Story |
| Nikki Barrett | Casting |
| Susie Figgis | Casting |
| Terry Rossio | Story |
| Geoff Zanelli | Original Music Composer |
| Paul Cameron | Director of Photography |
| Joseph M. Caracciolo Jr. | Executive Producer |
| Chad Oman | Executive Producer |
| Melissa Reid | Associate Producer |
| Terry Rossio | Executive Producer |
| Mike Stenson | Executive Producer |
| Brigham Taylor | Executive Producer |
| Ronna Kress | Casting |
| Nigel Phelps | Production Design |
| John Dexter | Art Direction |
| Ian Gracie | Art Direction |
| Jacinta Leong | Art Direction |
| Tom Nursey | Art Direction |
| Michael Turner | Art Direction |
| Shannon Gottlieb | Set Decoration |
| Penny Rose | Costume Design |
| Catherine Mullan | Animation Supervisor |
| Johnny Spinelli | Lead Animator |
| Sharia Lynn Davis | Assistant Editor |
| Peter Oso Snell | Music Editor |
| Ted Elliott | Characters |
| Stuart Beattie | Characters |
| Jay Wolpert | Characters |
| Alexandre Ronco | Animation Supervisor |
| Sebastian Trujillo | Lead Animator |
| Hannah d'Angerio | Casting Associate |
| Kirsty Kinnear | Casting Associate |
| Lucy Rands | Casting Associate |
| Carolina Häggström | Script Supervisor |
| Joecy Shepherd | Script Supervisor |
| Victoria Sullivan | Script Supervisor |
| Matthew Wollaston | Armorer |
| Craig Hosking | Aerial Coordinator |
| Rick Hicks | Marine Coordinator |
| Robert Wong | Marine Coordinator |
| Craig Hosking | Pilot |
| David Paris | Pilot |
| Scott Menzies | Pilot |
| Peter Beeh | Aerial Camera Technician |
| Hans Bjerno | Aerial Director of Photography |
| Steve Koster | Aerial Director of Photography |
| David B. Nowell | Aerial Director of Photography |
| Darrin Keough | Camera Operator |
| Calum McFarlane | Camera Operator |
| Richard Bradshaw | Camera Operator |
| Shaun Conway | Gaffer |
| Rafael E. Sánchez | Gaffer |
| Jonathan Spencer | Gaffer |
| Jeff Kuzyk | Gaffer |
| David Thomson | Rigging Grip |
| Rod Haney | Rigging Grip |
| Chris Haarhoff | Steadicam Operator |
| Andrew AJ Johnson | Steadicam Operator |
| Brad Shield | Second Unit Director of Photography |
| Peter Mountain | Still Photographer |
| Ian Seabrook | Underwater Camera |
| Reg Garside | Gaffer |
| John Gamble | Additional Photography |
| Giles Keyte | Additional Still Photographer |
| Stephen S. Campanelli | Additional Photography |
| Jason Talbert | Dolly Grip |
| Mal Booth | Dolly Grip |
| Michael Vivian | Dolly Grip |
| Chris Hansford | Dolly Grip |
| Toby Copping | Key Grip |
| J. Michael Popovich | Key Grip |
| Greg Tidman | Key Grip |
| Lucy Bowring | Assistant Costume Designer |
| Melody Koerber | Assistant Costume Designer |
| Rosie McArthur | Costume Coordinator |
| Darrell Warner | Costume Illustrator |
| Stacy Horn | Costume Supervisor |
| Lorraine Carson | Costume Supervisor |
| Carol Quiroz | Key Costumer |
| Saascha Wiki Kessell | Set Costumer |
| Dan Owen | Set Costumer |
| Roberta Shaw | Set Costumer |
| Samantha Walker | Set Costumer |
| Tanya Woelfle | Set Costumer |
| Rick Findlater | Hair Department Head |
| Peter Swords King | Hair Designer |
| Robert A. Pandini | Key Hair Stylist |
| Joel Harlow | Makeup Department Head |
| Peter Swords King | Makeup Designer |
| Gloria Pasqua Casny | Hairstylist |
| Ken Niederbaumer | Makeup Artist |
| Alice Baueris | Prosthetic Makeup Artist |
| Nikola Davis | Prosthetic Makeup Artist |
| Emily James | Prosthetic Makeup Artist |
| Damian Martin | Prosthetic Makeup Artist |
| Amy Vaughan | Prosthetic Makeup Artist |
| Colin Ware | Prosthetic Makeup Artist |
| Ron Barr | Digital Intermediate |
| Erik Rogers | Digital Intermediate |
| Stefan Sonnenfeld | Digital Intermediate |
| Jonny Winograd | First Assistant Editor |
| Tommy Aagaard | First Assistant Editor |
| Kenny G. Krauss | First Assistant Editor |
| Jacob Riehle | Dialogue Editor |
| David Forest | Visual Effects Editor |
| Joseph Hart Green | Visual Effects Editor |
| Christopher Raiche | Visual Effects Editor |
| Christina Graham | Visual Effects Producer |
| Tamara Watts Kent | Visual Effects Producer |
| Korey J. Cauchon | Visual Effects Producer |
| Annie Normandin | Visual Effects Producer |
| Max Leonard | Visual Effects Producer |
| Kim Menaster | Visual Effects Producer |
| Rebecca Scott | Visual Effects Producer |
| Eric Bruneau | Visual Effects Producer |
| Julie Cardinal | Visual Effects Producer |
| Gary Brozenich | Visual Effects Supervisor |
| Bill Kent | Visual Effects Supervisor |
| Sheldon Stopsack | Visual Effects Supervisor |
| Ryan Tudhope | Visual Effects Supervisor |
| Trent Claus | Visual Effects Supervisor |
| Patrick Ledda | Visual Effects Supervisor |
| Arne Kaupang | Visual Effects Supervisor |
| Laurent Spillemaecker | Visual Effects Supervisor |
| Dan Oliver | Special Effects Supervisor |
| Stephanie Flack | ADR Editor |
| Kimberly Harris | ADR Editor |
| Cheryl Nardi | ADR Editor |
| Marshall Winn | ADR Editor |
| Anna MacKenzie | ADR Supervisor |
| Katy Wood | ADR Supervisor |
| Sandra Portman | ADR Supervisor |
| Paradox Delilah | Boom Operator |
| David Butcherine | Boom Operator |
| John T. Cucci | Foley |
| Dan O'Connell | Foley |
| Luke Dunn Gielmuda | Foley Editor |
| Malcolm Fife | Foley Editor |
| E.J. Holowicki | Foley Editor |
| David Chrastka | Sound Effects Editor |
| Justin Doyle | Sound Effects Editor |
| Scott Guitteau | Sound Effects Editor |
| David C. Hughes | Sound Effects Editor |
| Baard H. Ingebretsen | Sound Effects Editor |
| Tormod Ringnes | Sound Effects Editor |
| Paul Massey | Sound Re-Recording Mixer |
| Scott Millan | Sound Re-Recording Mixer |
| Christopher Boyes | Sound Re-Recording Mixer |
| Christopher Boyes | Supervising Sound Editor |
| Jack Whittaker | Supervising Sound Editor |
| Jourdan Henderson | Art Department Coordinator |
| Tricia McInally | Art Department Coordinator |
| Richie Dehne | Property Master |
| Kris Peck | Property Master |
| Paul Jasper | Animal Coordinator |
| Michael Hansen | Utility Stunts |
| Stephen Oh | Camera Operator |
| Jeremy Johnson | Digital Compositor |
| Angela Moore | Stunts |
| Beverley Dunn | Set Decoration |
| Chantelle Slee | Stunts |
| Daniel Nelson | Stunts |
| Jack Kingsley | Stunts |
| Brittany Morris | Stunts |
| Mike Snow | Stunts |
| Charmian Gradwell | Dialect Coach |
| Michael Matthews | Stunts |
| Jessica Derhammer | Production Supervisor |
| Janene Carleton | Stunts |
| Krista Bell | Stunts |
| Owen Walstrom | Stunt Coordinator |
| Breanna Watkins | Stunt Double |
| Clint Carleton | Stunts |
| Rob Bliss | Concept Artist |
