 | Antonio Banderas als Puss in Boots (voice) |
 | Salma Hayek Pinault als Kitty Softpaws (voice) |
 | Zach Galifianakis als Humpty Dumpty (voice) |
 | Billy Bob Thornton als Jack (voice) |
 | Amy Sedaris als Jill (voice) |
 | Constance Marie als Imelda (voice) |
 | Mike Mitchell als Andy Beanstalk (voice) |
 | Rich Dietl als Bounty Hunter (voice) |
 | Guillermo del Toro als Comandante / Hombre del bigote (voice) |
 | Conrad Vernon als Raoul / Soldier (voice) |
 | Chris Miller als Little Boy Blue / Friar Miller / Prison Guard / Manuel / Rafael (voice) |
| Ryan Crego als Luis (voice) |
 | Tom Wheeler als Bartender / Mean Boy / Wagon Driver / Hotel Owner / Rodrigo (voice) |
 | Tom McGrath als Bar Thief (voice) |
 | Bob Joles als Giuseppe (voice) |
 | Latifa Ouaou als Crazy Woman / Mean Girl / Milk Lady / Little Boy (voice) |
| Jessica Schulte als Estella Maria (voice) |
 | Bob Persichetti als Ohhh Cat (voice) |
 | Nina Barry als Ivana / Charo (voice) |
 | Sergio Bruna als Soldier (voice) (uncredited) |
| Roberto Donati als Various (voice) (uncredited) |
 | Rebecca Davis als Various Cats (voice) (uncredited) |
 | Joshua Rush als Additional Voices (voice) (uncredited) |
 | Lara Jill Miller als Additional Voices (voice) (uncredited) |
 | Jossara Jinaro als Additional Voices (voice) (uncredited) |
 | Julie Wittner als Various Cats (voice) (uncredited) |
| Tom Wheeler | Screenplay |
| Henry Jackman | Original Music Composer |
| Erika Dapkewicz | Editor |
| Charles Perrault | Characters |
| Chris Miller | Director |
| Guillaume Aretos | Visual Development |
| William Davies | Story |
| Michelle Raimo Kouyate | Executive Producer |
| Andrew Adamson | Executive Producer |
| Latifa Ouaou | Producer |
| Tom Wheeler | Story |
| Guillermo del Toro | Executive Producer |
| Brian Lynch | Story |
| Tom Jacomb | Associate Producer |
| Christian Schellewald | Art Direction |
| Leslee Feldman | Casting |
| Guillaume Aretos | Production Design |
| John H. Williams | Co-Executive Producer |
| Joe M. Aguilar | Producer |
| Matthew Margeson | Additional Music |
| Milton E. Rodriguez-Rios | CG Supervisor |
| Erik Mattson | CG Supervisor |
| Alex Cardullo | Post Production Assistant |
| Olivier Staphylas | Supervising Animator |
| Matt Linder | Master Lighting Artist |
| Matt Robertson | Administration |
| Brittany Cope | Casting Assistant |
| Josephine Knight | Musician |
| Laura Gorenstein Miller | Choreographer |
| Othieno Okong'o | Systems Administrators & Support |
| Doug Yoshida | Lighting Artist |
| Kevin Edwards | Master Lighting Artist |
| Ariga Parseghian | Finance |
| Jessica Forer | Production Coordinator |
| Andrew Hotz | Production Supervisor |
| Rakesh S. Patil | Production Supervisor |
| Alyson Dee Moore | Foley |
| Jonathan Harman | CG Supervisor |
| Alissa Rowinsky Wright | Legal Services |
| Michelle Cabalu | Assistant Editor |
| Kirsten Drummond | Lighting Artist |
| Kieron Cheuk-Chi Lo | Lighting Artist |
| Amber Stewart Lunderville | Master Lighting Artist |
| James Beshears | Executive In Charge Of Post Production |
| Alyson Blume | Production Coordinator |
| Emily Conlon | Production Coordinator |
| Michael Lynn | Production Supervisor |
| Gary Kettel | Musician |
| Anna Behlmer | Sound Re-Recording Mixer |
| Allison Isenberg | Art Department Coordinator |
| Aayush Sharma | Lighting Artist |
| Praveen Dev | Lighting Artist |
| William E. Arias | Master Lighting Artist |
| Benjamin Lishka | Master Lighting Artist |
| Laura C. Denton | Production Coordinator |
| Ian J. McIntosh | Production Coordinator |
| Cathy Sitzes | Production Coordinator |
| Nicholas Fumia | Production Supervisor |
| Rachnatp | Production Supervisor |
| Christian Roedel | Production Supervisor |
| Richard King | Sound Designer |
| Richard King | Supervising Sound Editor |
| Liang-Yuan Wang | CG Supervisor |
| Nick Wollage | Score Engineer |
| Sean Sexton | Supervising Animator |
| Judah Mambu | Script Coordinator |
| Ashin Ashroff | Lighting Artist |
| Lyndon Li | Lighting Artist |
| Billy Brooks | Lighting Artist |
| Terri Anderson | Finance |
| Kirk Shalosky | Production Accountant |
| Matthew C. Campbell | Production Coordinator |
| Monalisa Kar | Production Coordinator |
| Caroline Robinson | Production Coordinator |
| Monica de Armond | Production Supervisor |
| Daniel Saxlid | Sound Re-Recording Mixer |
| Chad Hammes | Line Producer |
| Greg Lev | CG Supervisor |
| Peter Ramsey | Creative Consultant |
| Clint Colver | Lighting Artist |
| Justin Dobies | Lighting Artist |
| George Ho | Lighting Artist |
| Aliza Mills | Production Coordinator |
| Aditya Deosthale | Production Supervisor |
| Daniel Pinder | Music Editor |
| Mark Berrow | Musician |
| Tony Blondal | Orchestrator |
| Jules Woods | Sound Re-Recording Mixer |
| Teju Aloysius | Animation |
| David C. Lawson | CG Supervisor |
| John Hill | Supervising Animator |
| Dave Dinsmore | Systems Administrators & Support |
| Shane Glading | Lighting Artist |
| C. Jin Im | Lighting Artist |
| Max Bruce | Master Lighting Artist |
| Antoine Deschamps | Master Lighting Artist |
| Don Taylor | Master Lighting Artist |
| Cindy Azada Whitman | Production Supervisor |
| Carlos Sotolongo | ADR & Dubbing |
| Andrew Bock | First Assistant Sound Editor |
| Peter Lale | Musician |
| Tighe Sheldon | Sound Recordist |
| Marc Scott | CG Supervisor |
| Patrick Kelly | Software Engineer |
| Matt Johnson | Supervising Technical Director |
| Jessica Schulte | First Assistant Editor |
| Navjit Singh Gill | Lighting Artist |
| Soo Kyung Kim | Lighting Artist |
| Hannah Sherman | Lighting Artist |
| Darci Zalvin | Executive In Charge Of Production |
| John Roesch | Foley |
| John Barclay | Musician |
| Frank Ricotti | Musician |
| Dennis S. Sands | Scoring Mixer |
| Michael Babcock | Sound Effects Editor |
| Gil Zimmerman | Layout |
| Dominic Lewis | Additional Music |
| Igor Lodeiro | CG Supervisor |
| Gregory Yepes | CG Supervisor |
| Mona Shokrai | Legal Services |
| Bart Feliciano | Systems Administrators & Support |
| Shane Glick | Assistant Editor |
| Mayank Kanyal | Master Lighting Artist |
| Gabriel Portnof | Master Lighting Artist |
| Liza Breuninger | Production Accountant |
| T. Patrick Johnson | Production Coordinator |
| Kelly Cooney Cilella | Production Manager |
| Mark Pappas | Foley Editor |
| Drew Adams | Animation |
| Godwin Fernandes | Special Effects |
| Adarsh Abraham | Lighting Artist |
| Aneel Ramanath | Lighting Artist |
| Ozgur Ustundag | Master Lighting Artist |
| Benjamin Venancie | Master Lighting Artist |
| Rich Lee | Production Coordinator |
| Jon Eric Schmidt | Production Supervisor |
| Roy Latham | ADR & Dubbing |
| Gavin Greenaway | Conductor |
| Paul Clarvis | Musician |
| Patrick Bonneau | Animation |
| Margaret A. Decker | Software Engineer |
| Shawn Bohonos | Systems Administrators & Support |
| Lisa M. Tse | Lighting Artist |
| Ajay Upadhyay | Lighting Artist |
| Sebastien Chort | Master Lighting Artist |
| Matthew Clubb | Master Lighting Artist |
| Vicki Hunter | Finance |
| Adam Levy | Production Coordinator |
| David Hail | Publicist |
| Jeff Sawyer | Sound Effects Editor |
| Ariandy Chandra | Title Designer |
| Ken Ball | CG Supervisor |
| Monica Dejbakhsh | Legal Services |
| Xavier Vanegas | Production Intern |
| Gregg Carrier | Software Engineer |
| John O'Sullivan | Systems Administrators & Support |
| Jennifer Dolce | Associate Editor |
| Joe Monteleone | Associate Editor |
| Faris Ahmed | Lighting Artist |
| Brian Gee | Lighting Artist |
| Sondra Verlander | Lighting Artist |
| Mollie Gamo | Casting Assistant |
| Tripp Hudson | Executive In Charge Of Production |
| Rakesh S. Patil | Production Coordinator |
| Drew Puchalski | Production Coordinator |
| Sumit Verma | Production Coordinator |
| Roland N. Thai | Sound Effects Editor |
| James Bolt | Sound Re-Recording Mixer |
| Alex Belcher | Score Engineer |
| Rain Angeles | Systems Administrators & Support |
| Vijay Bundela | Lighting Artist |
| Ginka Kostova | Lighting Artist |
| Ka Yaw Tan | Lighting Artist |
| Matthieu Grospiron | Lighting Artist |
| Eric Roth | Master Lighting Artist |
| Tim Kwan | Production Coordinator |
| Milind D. Shinde | Production Manager |
| Linda Yeaney | First Assistant Sound Editor |
| Martin Loveday | Musician |
| Andy Nelson | Sound Re-Recording Mixer |
| Julien Bocabeille | Animation |
| Steven Hornby | Supervising Animator |
| Dj Downey | Systems Administrators & Support |
| Kurt Kaminski | Lighting Artist |
| Jessica Gallavan | ADR Supervisor |
| Ben Fordham | Musician |
| Michael W. Mitchell | Sound Effects Editor |
| Manuel Almela | Animation |
| Jason Anastas | Animation |
| Ludovic Bouancheau | Animation |
| Robert Lurye | CG Supervisor |
| David Farley | Post Production Supervisor |
| Alireza Estakhrian | Systems Administrators & Support |
| Stephen L. Meek | Associate Editor |
| Terry Claborn | Color Timer |
| Alexander Wu | Editorial Coordinator |
| Daniel Eaton | Lighting Artist |
| Germaine Franco | Musician |
| Tom Boyd | Musician |
| Tom Lalley | Sound Engineer |
| Joe Bowers | Animation |
| Laurent Caneiro | Animation |
| Christi Soper Hilt | Casting |
| Jonathan Fletcher Moore | Lighting Artist |
| Sharanya Viswamani | Lighting Artist |
| Pietro Materossi | Master Lighting Artist |
| Bonnie Lemon | Executive In Charge Of Production |
| Steph Gortz | Production Coordinator |
| Dinesh Krishnan Nair | Production Manager |
| Craig Rittenbaum | Production Manager |
| Jessie Carbonaro | Production Supervisor |
| George Doering | Musician |
| Rodrigo Huerta | Animation |
| Leif Jeffers | Animation |
| George Schermer | Animation |
| Sebastien Wojda | Animation |
| Nishant Khanna | VFX Artist |
| Celambarasan Ramasamy | VFX Artist |
| Amy Taylor | VFX Artist |
| Zhang Xiao | VFX Artist |
| Ramakrishna Yerramsetty | VFX Artist |
| Todd Gibbs | Visual Development |
| Devank Patel | Visual Effects |
| Chris Kirshbaum | Animation |
| Vaibhav Shah | Modeling |
| Evrim Akyilmaz | VFX Artist |
| Mitul Patel | VFX Artist |
| Katie Van Maanen | VFX Artist |
| Brian Walters | VFX Artist |
| Ken Bielenberg | VFX Supervisor |
| Philippe Gluckman | VFX Supervisor |
| Craig Elliott | Visual Development |
| Dominique Louis | Visual Development |
| Ken Fountain | Animation |
| Jayesh Jagdish Yatgiri | Animation |
| Trisha Butkowski | Creature Technical Director |
| John P. Rand | Modeling |
| Brian C. Davis | VFX Artist |
| Kenji Sweeney | VFX Artist |
| Paul Lasaine | Visual Development |
| Domin Lee | Visual Effects |
| Rahul Mullick | Visual Effects |
| Benjamin Willis | Animation |
| Nicolas A. Chauvelot | Animation Supervisor |
| Jung Jin Kang | Modeling |
| Charles Anderson | VFX Artist |
| Robert Chen | VFX Artist |
| Stephen Melagrano | Animation |
| Luke Randall | Animation |
| Mike Stern | Animation |
| Martin P. Hopkins | Animation |
| Gaurav Shenai | Creature Technical Director |
| Ferris Webby | Creature Technical Director |
| Nadja Bonacina | Modeling |
| Michael Losure | VFX Artist |
| Rahul Nair | VFX Artist |
| Shanmuga Raja | VFX Artist |
| James Hull | Animation |
| Jason Reisig | Animation |
| Laure Retif | Animation |
| Theodore Anthony Lee Ty | Animation |
| Greg Whittaker | Animation |
| Patrick Mate | Character Designer |
| Benjamin Andersen | VFX Artist |
| Erin Lehmkühl | VFX Artist |
| Baptiste Van Opstal | VFX Artist |
| Ronald A. Kurniawan | Visual Development |
| Renjith Chundakkad | Animation |
| Tommie Löfqvist | Animation |
| Marco Regina | Animation |
| Yash Agrawal | VFX Artist |
| Dustin Anderson | VFX Artist |
| Shaun Graham | Visual Effects |
| Zeki Melek | Visual Effects |
| Jacob K. Melvin | Visual Effects |
| John Patton | Visual Effects |
| Christopher Lee Capel | Animation |
| Eric Lees | Animation |
| Jeff Wagner | Modeling |
| Vikas Chandel | VFX Artist |
| Richard Daskas | Visual Development |
| Nathan Fowkes | Visual Development |
| David Couchariere | Animation |
| Manish Kumar | Animation |
| Roger Vizard | Animation |
| George Meppadath Kurian | Animation |
| Michael Leon Ware | Creature Technical Director |
| Gianni Aliotti | VFX Artist |
| Shiben Bhattacharjee | VFX Artist |
| Seth Lippman | VFX Artist |
| Dhruva Pathak | VFX Artist |
| Nikhil Sinha | VFX Artist |
| Tien Truong | VFX Artist |
| Shinsaku Arima | Visual Effects |
| Bill Tessier | Animation |
| Dick Walsh | Creature Technical Director |
| Craig Dowsett | Modeling |
| Wes Chilton | VFX Artist |
| Matt Head | VFX Artist |
| Sylvain Deboissy | Visual Development |
| Emil Mitev | Visual Development |
| Rachel Tiep-Daniels | Visual Development |
| Peter Zaslav | Visual Development |
| Onur Yeldan | Animation |
| James E. Stapp | Modeling |
| Philippe Brochu | Modeling |
| Mark Newport | VFX Artist |
| Marcos Mateu-Mestre | Visual Development |
| Ji Hyun Yoon | Visual Effects |
| Adam Dotson | Animation |
| Michael Kiely | Animation |
| Nideep Varghese | Animation |
| Mark Williams | Animation |
| Chellappan Senthilkumar | Creature Technical Director |
| Alessandro Pepe | VFX Artist |
| Arjun Thekkumadathil | VFX Artist |
| Kurt D. Williams | VFX Artist |
| Bill Diaz | Animation |
| Raffaella Filipponi | Animation |
| Mike Safianoff | Animation |
| Tony K. Williams | Character Modelling Supervisor |
| Dilip Lalwani | Creature Technical Director |
| Jason Porath | VFX Artist |
| Osamu Takehiro | VFX Artist |
| Yuchung Peter Chan | Visual Development |
| Collin Maxfield Parrish | Visual Effects |
| W. Jacob Gardner | Animation |
| James Cockerham | Creature Technical Director |
| Lee Gramling | Creature Technical Director |
| Ki Jong Hong | Modeling |
| Wendy Rogers | Pre-Visualization Supervisor |
| Jaemin Lee | VFX Artist |
| Madhavaro Bheesetti | Visual Effects |
| Zachary Carter | Visual Effects |
| Kyle Maxwell | Visual Effects |
| Willy Harber | Animation |
| Peer Lemmers | Animation |
| Karunakar Reddy | Animation |
| Javier Solsona | Creature Technical Director |
| Igor Stefanovic | Creature Technical Director |
| David Walden | Creature Technical Director |
| Greg Beckman | VFX Artist |
| Tyson Erze | VFX Artist |
| Stephanie Siebert | VFX Artist |
| Eric Deuel | Animation |
| Joe Sandstrom | Animation |
| Prasanjib Nag | Animation |
| Morgan R. Kelly | Animation |
| Tony Siruno | Character Designer |
| Landon Gray | VFX Artist |
| Zubin Wadia | VFX Artist |
| Chris Appelhans | Visual Development |
| Masahito Yoshioka | Visual Effects |
| Gil Zimmerman | Director of Photography |
| Michael Miller | ADR & Dubbing |
| Bob Persichetti | Head of Story |
| Ken Bielenberg | Visual Effects Supervisor |
| Fabio Lignini | Head of Animation |
| Gil Zimmerman | Head of Layout |
| Antony Gray | Supervising Animator |
| Mark Fattibene | Lighting Supervisor |
| Judah Mambu | Story Coordinator |
| Emily Conlon | Script Coordinator |
| Isis Mussenden | Costume Design |
| Christopher K. Jefferies | Production Supervisor |
| Rafael Chaidez | Production Supervisor |
| Kathryn Liotta | Production Supervisor |
| Dan Golembeski | Supervising Technical Director |
| Roger Tang | Music Coordinator |
| Philip Cohen | Production Supervisor |
| Rich Dietl | Associate Editor |
| Josh Wood | Post Production Assistant |
