 | John Wayne als Thomas Dunson |
 | Montgomery Clift als Matthew Garth |
 | Joanne Dru als Tess Millay |
 | Walter Brennan als 'Groot' Nadine |
 | Coleen Gray als Fen |
 | Harry Carey als Mr. Melville |
 | John Ireland als Cherry Valance |
 | Noah Beery Jr. als Buster McGee |
 | Harry Carey, Jr. als Dan Latimer |
 | Chief Yowlachie als Quo |
 | Paul Fix als Teeler Yacey |
 | Hank Worden als Simms Reeves |
 | Mickey Kuhn als Matt, as a boy |
 | Ray Hyke als Walt Jergens |
 | Hal Taliaferro als Old Leather |
 | Shelley Winters als Dance Hall Girl in Wagon Train (uncredited) |
 | Lane Chandler als Colonel (uncredited) |
 | Davison Clark als Mr. Meeker (uncredited) |
 | Harry Cording als Gambler (uncredited) |
 | Richard Farnsworth als Dunston Rider (uncredited) |
 | Paul Fierro als Fernandez (uncredited) |
 | George Lloyd als Rider with Melville (uncredited) |
 | Pierce Lyden als Colonel's Trail Boss (uncredited) |
| Frank Meredith als Train Engineer (uncredited) |
 | John Merton als Settler (uncredited) (uncredited) |
 | Jack Montgomery als Drover at Meeting (uncredited) |
| Ivan Parry als Bunk Kenneally (uncredited) |
 | Lee Phelps als Gambler (uncredited) |
| John Rice als Drover at Meeting (uncredited) |
| William Self als Sutter (uncredited) |
| Carl Sepulveda als Cowhand (uncredited) |
 | Ray Spiker als Wagon Train Member (uncredited) |
 | Glenn Strange als Naylor (uncredited) |
 | Tom Tyler als Quitter (uncredited) |
 | Dan White als Laredo (uncredited) |
 | Guy Wilkerson als Pete (uncredited) |
| Shelley Winters als Wagon Train Member (uncredited) |
| Howard Hawks | Director |
| Borden Chase | Screenplay |
| Charles Schnee | Screenplay |
| Howard Hawks | Producer |
| Charles K. Feldman | Executive Producer |
| Russell Harlan | Director of Photography |
| Christian Nyby | Editor |
| Arthur Rosson | Co-Director |
| John Datu | Art Direction |
| Margaret Martin | Hair Department Head |
| Al Hersh | Props |
| Thol Simonson | Special Effects Technician |
| Borden Chase | Story |
| Dimitri Tiomkin | Original Music Composer |
| Francis D. Lyon | Editor |
| Jack Murray | Editor |
| Dave Gunreth | Casting |
| Lee Greenway | Makeup Artist |
| George Bau | Assistant Makeup Artist |
| Don L. Cash | Makeup Department Head |
| Mary Freeman | Hairstylist |
| Dotha Hippe | Hairstylist |
| Frank La Rue | Makeup Artist |
| Anna Malin | Key Hair Stylist |
| Margaret Martin | Hairdresser |
| Maudlee McDougall | Assistant Hairstylist |
| Web Overlander | Makeup Artist |
| Norman A. Cook | Production Manager |
| M.W. Kennedy | Assistant Production Manager |
| Walter Mayo | Production Manager |
| William McGarry | Assistant Director |
| Joseph C. Cavalier | Second Assistant Director |
| Arthur Rosson | Second Unit Director |
| Arthur Siteman | Second Unit Director |
| Joe Wonder | Assistant Director |
| John F. Austin | Set Dresser |
| Jack Colconda | Props |
| Lester Hallett | Assistant Property Master |
| Howard Harbough | Standby Painter |
| Richard DeWeese | Sound |
| Earl Crain Jr. | Boom Operator |
| Larry Gannon | Cableman |
| Jack Gard | Boom Operator |
| Slim Houghton | Cableman |
| Cecil Shephard | Cableman |
| Frank Webster | Sound Mixer |
| Kenneth C. Wesson | Sound Recordist |
| Donald Steward | Special Effects |
| Allen Q. Thompson | Special Effects |
| Richard Farnsworth | Stunt Double |
| Riley R. Waters | Stunt Double |
| Pete Bernard | Grip |
| Ray Binger | Additional Director of Photography |
| Roy Black | Gaffer |
| George T. Clemens | Camera Operator |
| Cleo Crabtree | Gaffer |
| Bert Eason | Assistant Camera |
| Robert Rhea | Assistant Camera |
| Earl Stafford | Assistant Camera |
| Palmer 'Pete' Swenson | Best Boy Electric |
| John D. Weiler | Camera Operator |
| Chuck Arrice | Wardrobe Assistant |
| Howard Child | Wardrobe Assistant |
| Wesley Jeffries | Wardrobe Master |
| Saul Jick | Tailor |
| Adele Parmenter | Wardrobe Master |
| Nevada Penn | Wardrobe Assistant |
| Fred Starns | Wardrobe Master |
| John Zacha | Wardrobe Master |
| Barbara Ford | Assistant Editor |
| Stewart S. Frye | Assistant Editor |
| Olive Hofmann | Negative Cutter |
| Gus Schroeder | Location Manager |
| Dimitri Tiomkin | Music Director |
| Lucien Cailliet | Orchestrator |
| Paul Marquardt | Orchestrator |
| Howard Hawks | Presenter |
| Howard Alston | Accountant |
| Sid Davis | Stand In |
| Betty Evans | Accountant |
| Josephine Woods | Production Secretary |
| Carol Henry | Stunts |
| Sid Davis | Stunts |
| Cliff Lyons | Stunts |
| Danny Sands | Stunts |
| Chuck Roberson | Stunts |
| Jack Williams | Stunts |
