 | Jennifer Aniston als Sarah Huttinger |
 | Kevin Costner als Beau Burroughs |
 | Shirley MacLaine als Katharine Richelieu |
 | Mark Ruffalo als Jeff Daly |
 | Richard Jenkins als Earl Huttinger |
 | Christopher McDonald als Roger McManus |
 | Steve Sandvoss als Scott |
 | Mena Suvari als Annie Huttinger |
 | Mike Vogel als Blake Burroughs |
 | Rob Lanza als New Year's Eve M.C. |
 | Lisa Vachon als Young Katherine |
| Trevor Stock als Young Beau |
 | Jennifer Taylor als Jocelyn Richelieu |
 | Marcia Ann Burrs als Pasadena Wife |
 | Lynn Wanlass als Pasadena Wife |
 | Mary Anne McGarry als Pasadena Wife |
 | Maree Cheatham als Party Guest |
| Gloria Grant als Party Guest |
 | Gregory White als Party Guest |
| Jake Mailey als Party Guest |
 | Frank Novak als Party Guest |
| Billy Kerr als Party Guest |
 | Terrie Snell als Party Guest |
 | Shannon Farnon als Party Guest |
 | Jenny Wade als Nikki |
 | Erinn Bartlett als Donna |
| Allyson Bradford als Bridesmaid |
 | Kate McClafferty als Bridesmaid |
 | Googy Gress als Burly Man |
 | Rolando Molina als Mover |
| Carmela Rappazzo als Party Planner |
 | Erinn Hayes als Wedding Coordinator |
 | Christopher Stapleton als Bartender |
| George F. Regas als Pastor |
 | Jaime Ray Newman als Conference Greeter |
 | Andy Milder als Conference Attendee |
 | Gabriel Jarret als Conference Attendee |
 | Clyde Kusatsu als Conference Attendee |
 | John Sterling Carter als Conference Attendee |
| Mike Baldridge als Reporter |
 | Donna Cooper als Reporter |
| Erin McDonald als Waitress |
 | Paul Ganus als Co-Pilot |
| Amos Levkovitch als Magician |
 | Leigh French als Charity Dinner Guest |
| Charlotte Colavin als Charity Dinner Guest |
 | George Gerdes als Charity Dinner Guest |
 | Lyman Ward als Charity Dinner Guest |
 | Jordan Lund als Charity Dinner Guest |
| John E. Byrd als Doorman |
 | Kathy Bates als Aunt Mitsy (uncredited) |
 | Colleen Camp als Pasadena Wife (uncredited) |
 | George Hamilton als Self (uncredited) |
| Robert Leighton | Editor |
| Paula Weinstein | Producer |
| Ted Griffin | Screenplay |
| Rob Reiner | Director |
| Ben Cosgrove | Producer |
| Marc Shaiman | Original Music Composer |
| Peter Deming | Director of Photography |
| Thomas E. Sanders | Production Design |
| Lisa Lovaas | Costume Supervisor |
| Dick Ziker | Stunt Coordinator |
| George Clooney | Executive Producer |
| Jane Jenkins | Casting |
| Janet Hirshenson | Casting |
| Kym Barrett | Costume Design |
| Nellie McKay | Songs |
| Frank Capra III | Co-Producer |
| Steven Soderbergh | Executive Producer |
| Jennifer Fox | Executive Producer |
| Michael I. Rachmil | Executive Producer |
| Len Amato | Executive Producer |
| Robert Kirby | Executive Producer |
| Bruce Berman | Executive Producer |
| Richard J. Gelfand | Unit Production Manager |
| Frank Capra III | First Assistant Director |
| Mike Topoozian | First Assistant Director |
| Basil Grillo | Second Assistant Director |
| Gregory Kent Simmons | Second Assistant Director |
| Chris Douridas | Music Supervisor |
| Thomas P. Wilkins | Art Direction |
| Robert Strohmaier | Assistant Art Director |
| Jay Hart | Set Decoration |
| Josh Lusby | Set Designer |
| Jim Yarmer | Set Designer |
| Jeff Bilger | Second Second Assistant Director |
| Dieter Busch | Second Second Assistant Director |
| Jody Spilkoman | Second Second Assistant Director |
| John Robotham | Stunt Coordinator |
| Steve Cantamessa | Sound Mixer |
| Lon Bender | Supervising Sound Editor |
| Tricia Ronten | Script Supervisor |
| Angela Levin | Makeup Department Head |
| Stephen M. Kelley | Key Makeup Artist |
| Stephen M. Kelley | Makeup Artist |
| Valli O'Reilly | Makeup Artist |
| Francisco X. Pérez | Makeup Artist |
| Ben Nye Jr. | Makeup Artist |
| Linda De Andrea | Hair Department Head |
| Hazel Catmull | Key Hair Stylist |
| Chris McMillan | Hairstylist |
| Elle Elliott | Hairstylist |
| Cydney Cornell | Hairstylist |
| Eric Durst | Visual Effects Supervisor |
| Tricia Miles | Post Production Supervisor |
| Marc Fishman | Sound Re-Recording Mixer |
| Tony Lamberti | Sound Re-Recording Mixer |
| Patrick Cusack | Assistant Sound Editor |
| Dino DiMuro | Sound Effects Editor |
| Geoffrey G. Rubay | Sound Effects Editor |
| David Esparza | Sound Effects Editor |
| Jocelyn E. Thomas | Casting Assistant |
| Sande Alessi | Extras Casting |
| Michelle Lewitt | Casting Associate |
| Kristan Berona | Extras Casting |
| Jennifer Alessi | Extras Casting |
| Mark Brooks | Set Dresser |
| Bob Gorelick | "A" Camera Operator |
| Bob Gorelick | Steadicam Operator |
| Melissa Moseley | Still Photographer |
| David Eubank | First Assistant "A" Camera |
| Alan R. Disler | First Assistant "B" Camera |
| Lisa K. Ferguson | Second Assistant "A" Camera |
| Eric Amundsen | Second Assistant "B" Camera |
| Danny Miller | First Assistant Editor |
| Gregg London | Assistant Editor |
| Corinne Villa | Assistant Editor |
| Shaun Aprahamian | Assistant Editor |
| Gary Thomas | Boom Operator |
| Laura Baker | Key Costumer |
| Holly Davis | Key Costumer |
| Lisa D. Quercioli | Key Costumer |
| Tony Velasco | Key Costumer |
| Sabine Huber | Costumer |
| Phillip Howard | Costumer |
| Dalhia Schuette | Costumer |
| Annie Laoparadonchai | Costumer |
| Barbara Gordon | Costumer |
| Pete Anthony | Conductor |
| Pete Anthony | Orchestrator |
| Jeff Atmajian | Orchestrator |
| Harvey Cohen | Orchestrator |
| Nick Vidar | Music Programmer |
| Scott Stambler | Music Editor |
| Stephanie Lowry | Music Editor |
| Mo Henry | Negative Cutter |
| David Orr | Color Timer |
| Scott Gregory | Digital Colorist |
| Cody H. Carolin | Set Production Assistant |
