 | Dylan O'Brien als Thomas |
 | Kaya Scodelario als Teresa Agnes |
 | Ki Hong Lee als Minho |
 | Aml Ameen als Alby |
 | Blake Cooper als Chuck |
 | Thomas Brodie-Sangster als Newt |
 | Will Poulter als Gally |
 | Dexter Darden als Frypan |
 | Chris Sheffield als Ben |
 | Joe Adler als Zart |
 | Alexander Flores als Winston |
 | Jacob Latimore als Jeff |
 | Randall D. Cunningham als Clint |
 | Patricia Clarkson als Ava Paige |
 | Don McManus als Masked Man |
 | Michael Bow als Glader |
 | Jerry Clark als Glader |
 | Michael Deville als Glader |
| Dylan Gaspard als Glader |
| Cory Gooding als Glader |
 | Cazi Greene als Glader |
| Dustin Guitreau als Glader |
| Tyler Harrison als Glader |
| Landon Hazel als Glader |
| Gary Hood als Glader |
| Nick Killebrew als Glader |
| John Langston als Glader |
| Chad Martinez als Glader |
| Lester Millet als Glader |
| Sawyer Pierce als Glader |
| Weston Rachal als Glader |
 | Bryce Romero als Glader |
| Johnny Stockwell als Glader |
| SanChavis Torns als Glader |
| Lane Westerhaus als Glader |
| Gentry Williams als Glader |
 | Adriana Acosta als Glader (uncredited) |
| Duane Cothren als Conference Room Parent (uncredited) |
| James Dashner als Lab Tech (uncredited) |
 | Mark Gibson als Glader (Alec) (uncredited) |
| Darryl Harvey als Maze Control Room Supervisor / EMT (uncredited) |
| Janet L'Aube als Lab Scientist (uncredited) |
 | Travis Michael Myers als Glader (uncredited) |
| Zach Nichols als Glader (uncredited) |
 | Tommy Sheppard als Conference Room Member (uncredited) |
| Andrew Varenhorst als Patient Zero (uncredited) |
 | Carol Jean Wells als Herself Lab Student (uncredited) |
| Jeff Wiesen als Glader (uncredited) |
| Noah Oppenheim | Screenplay |
| Wes Ball | Director |
| Grant Pierce Myers | Screenplay |
| Lindsay Williams | Producer |
| T.S. Nowlin | Screenplay |
| James Dashner | Novel |
| Stephen S. Campanelli | Camera Operator |
| Mariana Sánchez de Antuñano | Camera Operator |
| Marty Bowen | Producer |
| Lee Stollman | Producer |
| William Burck | Sculptor |
| Russ Doyle | Greensman |
| Ai-Ling Lee | Sound Designer |
| Enrique Chediak | Director of Photography |
| Ron Bartlett | Sound Re-Recording Mixer |
| Scott Puckett | Visual Effects Producer |
| Simonetta Mariano | Costume Design |
| Michelle C. Harmon | Set Designer |
| Bonnie Marquette | Location Manager |
| Wright McFarland | Set Designer |
| Chuck Michael | Sound Effects Editor |
| Troy Robinson | Stunt Coordinator |
| Andy Ryan | Gaffer |
| Dan Zimmerman | Editor |
| David Keith Broome | Greensman |
| Christine Bieselin Clark | Costume Design |
| Christal Wolgamott | Visual Effects Producer |
| Sue Rowe | Visual Effects Supervisor |
| Priscilla John | Casting |
| Anthony Ortiz | Boom Operator |
| Ted Caplan | Music Editor |
| Kizzie Autumn Martin | Set Costumer |
| Jon Danniells | Set Decoration |
| Stacy Kelly | Makeup Department Head |
| Terri De Haan | Costume Supervisor |
| Ellen Goldsmith-Vein | Producer |
| Britany Viguerie | Set Costumer |
| Simonette Berry | Sculptor |
| Eric Brevig | Visual Effects Supervisor |
| Denise Chamian | Casting |
| Dan O'Connell | Foley |
| Lauri Mills | Studio Teachers |
| Marc Fisichella | Production Design |
| Douglas Cumming | Art Direction |
| Noah Bradley | Construction Coordinator |
| Jessica Navran | Assistant Art Director |
| John T. Cucci | Foley |
| Nancy Breaux | Script Supervisor |
| Steve Gehrke | Script Supervisor |
| Joe Hartwick Jr. | Executive Producer |
| Eddie Gamarra | Executive Producer |
| John Paesano | Original Music Composer |
| Wyck Godfrey | Producer |
| Ollie Rankin | CG Supervisor |
| Ferdinand Duplantier Jr. | Rigging Gaffer |
| Logan Breit | Visual Effects Editor |
| Steve Winsett | Makeup Effects |
| Steve McLeod | Visual Effects Editor |
| Christopher Dooly | Makeup Effects |
| Eric D. Christensen | Visual Effects Supervisor |
| Greg Morris | Additional Camera |
| Budd Bird | Hairstylist |
| Lauren Thomas | Makeup Effects |
| Gayle Munro | Visual Effects Producer |
| Dylan Goss | Helicopter Camera |
| Amy Wood | Hairstylist |
| Lisa Tutunjian | Digital Intermediate |
| Lucy O'Reilly | Makeup Artist |
| Greg Maloney | Visual Effects Producer |
| Ben Rothstein | Still Photographer |
| Aimee Stuit | Makeup Artist |
| Jeff Ranasinghe | CG Supervisor |
| P.J. Burch | First Assistant Editor |
| Jason Chen | Visual Effects Producer |
| Erik De Boer | Animation Supervisor |
| Michael Umble | Unit Publicist |
| Tim Gomillion | Sound Recordist |
| Vanessa Lapato | ADR Supervisor |
| Susan Dawes | Supervising Dialogue Editor |
| Helen Luttrell | Dialogue Editor |
| Michael Sabo | Property Master |
| Bobby Talbert | Stunts |
| Shane Daniels | Stunts |
| Monty L. Simons | Stunts |
| Greg Rementer | Stunts |
| Kortney Manns | Stunts |
| Preston Schrag | Stunts |
| Greg Dela Riva | Stunts |
| Aaron Matthews | Stunts |
| Mallory Thompson | Stunts |
| Tony Vo | Stunts |
| Josh Mueller | Stunts |
| Eric Salas | Stunts |
| Felipe Savahge | Stunts |
| Thirl Haston | Stunts |
| Mark De Alessandro | Stunts |
| Ashley Nicole Hudson | Stunts |
| Meredith Richardson | Stunts |
| Kevin Waterman | Stunts |
| H.H. Cooper | First Assistant Director |
| Mirashyam Blakeslee | Second Assistant Director |
| Chris Craine | Assistant Art Director |
| Matt Zaff | On Set Dresser |
| Stephen P. Durante | Leadman |
| Gus Coto | On Set Dresser |
| Patrick Calabrese | Set Dresser |
| Kevin C. Lang | Set Dresser |
| Scotty Morris | Set Dresser |
| Joel Venti | Storyboard Artist |
| Erin Foster | Art Department Coordinator |
| Vanessa Hickey | Second Second Assistant Director |
| Curtis Abbott | Digital Imaging Technician |
| Paul Ledford | Production Sound Mixer |
| David McKimmie | Post Production Supervisor |
| John A. Larsen | Supervising Sound Editor |
| Ai-Ling Lee | Supervising Sound Editor |
| Doug Hemphill | Sound Re-Recording Mixer |
| Beau Harrison | Assistant Property Master |
| Edward Poveda | Payroll Accountant |
| David Guilbeau | Craft Service |
| Sid Yost | Animal Wrangler |
| Edward O'Donnell | Transportation Coordinator |
| Doug Wright | Transportation Captain |
| Wayne Lemmer | Sound Effects Editor |
| Matthew Harrison | Foley Editor |
| Galen Goodpaster | First Assistant Sound Editor |
| David Wolowic | Assistant Sound Editor |
| Richard Duarte | Foley Mixer |
| John Guentner | Foley Mixer |
| Blake Collins | Foley Mixer |
| David Betancourt | ADR Mixer |
| Charleen Richards-Steeves | ADR Mixer |
| Christine Sirois | ADR Recordist |
| David Lucarelli | ADR Recordist |
| Loan Phan | Digital Intermediate Producer |
| Hiroshi Mori | Visual Effects |
| Bailey Domke | Special Effects Makeup Artist |
