 | Seth Rogen als Frank / Sergeant Pepper (voice) |
 | Kristen Wiig als Brenda (voice) |
 | Jonah Hill als Carl (voice) |
 | Bill Hader als Firewater / Tequila / El Guaco (voice) |
 | Michael Cera als Barry (voice) |
 | James Franco als Druggie (voice) |
 | Danny McBride als Honey Mustard (voice) |
 | Craig Robinson als Grits (voice) |
 | Paul Rudd als Darren (voice) |
 | Nick Kroll als Douche (voice) |
 | David Krumholtz als Kareem Abdul Lavash (voice) |
 | Edward Norton als Sammy Bagel Jr. (voice) |
 | Salma Hayek Pinault als Teresa Taco (voice) |
 | Anders Holm als Troy (voice) |
 | Scott Underwood als Gum / Twink / Krinkler's Chips / Pizza (voice) |
 | Sugar Lyn Beard als Baby Carrot / Cookies (voice) |
 | Conrad Vernon als Toilet Paper / Sauerkraut / Catcall Sausage / Grape #1 / Beer Can / Pop Bottle (voice) |
 | Ian James Corlett als Apple / Tickilish Licorice / Relish / Bag of Dog Food (voice) |
 | Michael Daingerfield als Chunk Munchers Cereal / Light Bulb / Indian Chutney (voice) |
 | Jason Simpson als Plum #2 / Beer Keg / Fat Guy / Fit Man (voice) |
 | Vincent Tong als Pislitz Chips / Juice Box / Jamaican Rum (voice) |
 | Karen E. Wright als Diner Waitress |
 | Lauren Miller als Camille Toh / Tampon (voice) |
 | Sam Vincent als Old Pork Sausage / Refried Beans / Sandwich / Pop Tart / Licorice Rope (voice) |
 | Greg Tiernan als Potato / Noodle Soup (voice) |
 | Brian Dobson als Italian Tomato / Lettuce (voice) |
 | Harland Williams als Ketchup / Drug Dealer / Baba Ganoush (voice) |
 | Alistair Abell als Mariachi Salsa / Gefilte Fish (voice) |
 | Iris Apatow als Berry Good Candies / Grape #3 / Coconut Milk (voice) |
 | Michael Dobson als Queso (voice) |
 | Ian Hanlin als Beet (voice) |
 | Maryke Hendrikse als Popped Cherry Mixer / Plum #1 / Loretta Bun / Frozen Fruitz (voice) |
 | Nicole Oliver als Sally Bun / Ice Cream / Watermelon / Female Shopper #1 (voice) |
 | Kelly Sheridan als Roberta Bun / Grape #2 / Female Shopper #2 (voice) |
 | Meat Loaf als Meatloaf (voice) (uncredited) |
| Conrad Vernon | Director |
| Greg Tiernan | Director |
| Kyle Hunter | Screenplay |
| Seth Rogen | Story |
| Evan Goldberg | Story |
| Ariel Shaffir | Screenplay |
| Andrew Blodget | Animation |
| Evan Goldberg | Producer |
| James Sathre | Lighting Technician |
| Jeff Bailey | Animation Supervisor |
| Jonah Hill | Executive Producer |
| Seth Rogen | Producer |
| Kyle McQueen | Art Direction |
| Arlyn Bantog | Production Manager |
| Todd Demong | Storyboard |
| Scott Armstrong | Layout |
| Pilar Flynn | Co-Producer |
| Kevin Pavlovic | Editor |
| David Distenfeld | Executive Producer |
| Megan Ellison | Producer |
| Aadel Forootan | Animation Manager |
| Kyle Hunter | Executive Producer |
| Nicole Stinn | Line Producer |
| Ariel Shaffir | Executive Producer |
| Avner Engel | Animation |
| Conrad Vernon | Producer |
| Jay Floyd | Administration |
| Anthony Di Ninno | Layout |
| Rodrigo Goncalves Venceloski | Animation |
| Seyed Alireza Meraji | Animation |
| Claire Niebergall | Animation |
| Crystal Sing | Animation |
| Robin Badr | Animation |
| Honey Khadem | VFX Artist |
| Darren Schmidtz | Animation |
| Christopher Lennertz | Original Music Composer |
| Bert Van Brande | Visual Effects Supervisor |
| Gabe Hilfer | Music Supervisor |
| Alan Menken | Original Music Composer |
| Jonah Hill | Story |
| Seth Rogen | Screenplay |
| Jillian Longnecker | Co-Producer |
| Alex McAtee | Co-Producer |
| Michael Linton | Animation |
| Evan Goldberg | Screenplay |
| Tarek Elaydi | CG Supervisor |
| Sarah Dougan | Editorial Coordinator |
| Ellery Van Dooyeweert | First Assistant Editor |
| Drew Tobin | Lighting Artist |
| James Weaver | Executive Producer |
| Guillermo Soria | Lighting Artist |
| Christopher Brooks | Music Editor |
| Andrew Harvey | Production Manager |
| Nicholas Hogan | Animation |
| Rory McGrath | Animation |
| Matthew Bass | Thanks |
| Jason Cox | Thanks |
| Grace Schoorl | Production Coordinator |
| Shelley Ann Taylor | Casting |
| Meg Walls | Production Coordinator |
| Vladimir Haintz | Animation |
| Kristy Osten | Animation |
| Alex Pepin | Animation |
| Dylan Kurp | Modeling |
| Phillip Bladh | Thanks |
| Nikki Eckstein | Production Coordinator |
| Liam Callander | Production Coordinator |
| Miriam Kallweit | Production Coordinator |
| Adriana Soto | Animation |
| Chelsea Barnard | Thanks |
| Chanel Raisin | Thanks |
| Mary Nelson-Duerrstein | Negative Cutter |
| Amanda Fujita | Lighting Artist |
| Gregg Barbanell | Foley |
| Francine Maisler | Casting |
| Shaun Gordon | Post Production Supervisor |
| Phillip Bladh | Production Sound Mixer |
| Tony R. Flemming | Animation |
| Tuan Anh Trinh | Animation |
| Mykie Yatco | Animation |
| Christopher Miller | Thanks |
| Matt Tolmach | Thanks |
| Kenny Chang | Lighting Supervisor |
| Arian Fay | Production Coordinator |
| Kitt Holeman | Production Coordinator |
| Rita Lin | Lighting Artist |
| Giai Jeff Wong | Animation |
| Steve Wittmann | Animation Supervisor |
| Mary Pat Bentel | Thanks |
| Katie Byron | Thanks |
| Jason Mantzoukas | Thanks |
| Luis Alberto De La Cerda | Lighting Artist |
| Samantha Liu | Title Designer |
| Kristy Osten | Animation |
| Maritza Louis | Modeling |
| B. Ted Deiker | Thanks |
| Stacy Thompson | Production Coordinator |
| David Werntz | Sound Effects Designer |
| Ryan Collins | Sound Effects Editor |
| Craig Braginsky | Additional Music |
| Fahad Haddad | Animation |
| Jason Thomas Campbell | Animation |
| Uri Alonim | Animation |
| Ling Hsu | Animation |
| Alex Kamien | Animation |
| Florian Parrot | Animation |
| Theodore Bressman | Thanks |
| Wayne Vincenzi | Lighting Artist |
| Felipe Ruiz Reyes | Master Lighting Artist |
| Mayleen Ahoy | Production Accountant |
| Alec Rubay | Foley Editor |
| Bart Samolis | Musician |
| James Morioka | Supervising Dialogue Editor |
| Megan Johnson | Animation |
| Cheng Ye | Modeling |
| Lisa Goldberg | Thanks |
| Michael A. Webber | Thanks |
| Sandra Kaufman | Assistant Editor |
| Sarah Dougan | Script Coordinator |
| Anurag Jadhav | Animation |
| Kari Rust | Animation |
| Prasad Thangeti | Animation |
| Stephne Wood | Animation |
| Eric Kissack | Thanks |
| Phil Lord | Thanks |
| Ricky Mabe | Thanks |
| Bruce Franklin | Line Producer |
| Joi McMillon | Assistant Editor |
| Katherine Rose | Foley |
| Pushkar Atre | Animation |
| David Browning | Animation |
| Laura McColm | Animation |
| Hao Wang | Animation |
| Andrew J. Cohen | Thanks |
| Jonathan Coyne | Thanks |
| Ben Karlin | Thanks |
| Jonathan Navarro | Lighting Artist |
| Anastasia Zubenko | Lighting Artist |
| Daryl B. Kell | Music Editor |
| Brandon Walz | Boom Operator |
| Ryan Guzdzial | First Assistant Camera |
| Sheena Singh | Production Coordinator |
| Emily Yakashiro | Production Coordinator |
| Wiley Townsend | Animation |
| Will Reiser | Thanks |
| Nate Barnard | CG Supervisor |
| Giorgio Rivalta | Lighting Artist |
| Nathan Dorfer | Animation |
| Cory Goodwin | Animation |
| Anurag Jadhav | Animation |
| Ken Franchi | Thanks |
| John Garret Gorman | Thanks |
| Mark Osborne | Thanks |
| Kathleen Steele | Production Coordinator |
| Jose De Mireles Lara | Animation |
| Dylan Kurp | Modeling |
| Jacquie Doyle | Visual Development |
| Deb Adair | Sound Re-Recording Mixer |
| Michael Kiely | Animation Supervisor |
| Edgardo Ulloa | Animation |
| Jennifer Pagan | Animation |
| Craig Kellman | Lead Character Designer |
| Jerrod Carmichael | Thanks |
| Joi McMillon | Thanks |
| Jenn Storm | Assistant Editor |
| Gregory Klein | Lead Animator |
| Chanel Raisin | Script Supervisor |
| Connor Ferguson | Animation |
| Rishi Kaul | Animation |
| Pearce Perkins | Animation |
| Morgan Ratsoy | Animation |
| Dmytro V. Sirenko | Visual Development |
| Larkin Donley | Thanks |
| Dawn Subhasiriwatana | Thanks |
| Anthony Bauyon | Assistant Editor |
| Mallory Mahar | Lighting Artist |
| Michael Chow | Production Accountant |
| Chris Carpenter | Sound Re-Recording Mixer |
| Caroline Jarvis | Animation |
| Eugen Sasu | Animation |
| Jimmy Wu | Animation |
| Mitch Yager | Animation |
| Cale Finot | Thanks |
| Tom McGrath | Thanks |
| Amy Pascal | Thanks |
| Adam Jordan | Thanks |
| Michael Donovan | Local Casting |
| Kyle Fox | Lighting Artist |
| Mike Cachuela | Storyboard Artist |
| Scott Underwood | Storyboard Artist |
| Doug Delaney | Additional Colorist |
| Mark Osborne | Lighting Supervisor |
