 | Tobin Bell als John Kramer / Jigsaw |
 | Costas Mandylor als Mark Hoffman |
 | Betsy Russell als Jill Tuck |
 | Cary Elwes als Dr. Lawrence Gordon |
 | Sean Patrick Flanery als Bobby Dagen |
 | Chad Donella als Gibson |
 | Chester Bennington als Evan |
 | Gina Holden als Joyce |
 | Dean Armstrong als Cale |
 | Naomi Snieckus als Nina |
 | Oluniké Adeliyi als Sidney |
 | Rebecca Marshall als Suzanne |
 | Anne Lee Greene als Dina |
 | Sebastian Pigott als Brad |
 | Jon Cor als Ryan |
 | Kevin McGarry als Charlie |
 | Dru Viergever als Dan |
 | Laurence Anthony als Rogers |
| Gabby West als Kara |
| Benjamin Clost als Jake |
 | Kim Schraner als Palmer |
 | James Van Patten als Dr. Heffner |
 | Ishan Morris als Alex |
 | Carlos Diaz als Coroner Worker |
| Christine Simpson als Donna Evans |
| Elizabeth Rowin als Sara |
| Jacintha Wesselingh als Newscaster #1 |
 | Claudia DiFolco als Newscaster #2 |
| Kimberly D'Eon als Newscaster #3 |
 | Rachel Wilson als Mother |
 | Alli Chung als Business Woman |
 | Desmond Campbell als Business Man |
| Billy Oliver als Policer Officer #1 |
| Liise Keeling als Police Officer #2 |
 | Tanedra Howard als Simone |
 | Shauna MacDonald als Tara |
 | Joanna Douglas als Joan |
 | Greg Bryk als Mallick |
 | Janelle Hutchison als Addy |
 | Larissa Gomes als Emily |
 | Kevin Rushton als Trevor |
| Jagger Gordon als Survivor Group Member #1 |
| Kyle Cicerella als Survivor Group Member #2 |
| Simone Steene als Survivor Group Member #3 |
 | Simon Northwood als Lead SWAT Officer |
 | Regan Moore als SWAT Officer |
 | Danny Lima als SWAT Officer |
| Bryan J. Thomas als SWAT Officer |
| Wayne Downer als SWAT Officer |
| Patrick Mark als SWAT Officer |
| Christopher McGuire als SWAT Officer |
| Don Gough als Limo Driver |
| David Gale als Additional Voice Talent (voice) |
| Shelley Hoffman als Additional Voice Talent (voice) |
 | Michael A. Miranda als Additional Voice Talent (voice) |
 | Chris Owens als Additional Voice Talent (voice) |
| Catherine Rix als Additional Voice Talent (voice) |
 | Kent Staines als Additional Voice Talent (voice) |
 | Michael Emerson als Zep Hindle (archive footage) (uncredited) |
 | Franky G als Xavier Chavez (archive footage) (uncredited) |
 | Erik Knudsen als Daniel Matthews (archive footage) (uncredited) |
 | Bahar Soomekh als Lynn Denlon (archive footage) (uncredited) |
 | Leigh Whannell als Adam Stanheight (archive footage) (uncredited) |
| Marcus Dunstan | Screenplay |
| Patrick Melton | Screenplay |
| Kevin Greutert | Director |
| Mark Burg | Producer |
| Oren Koules | Producer |
| Peter Block | Executive Producer |
| Daniel J. Heffner | Executive Producer |
| Stacey Testro | Executive Producer |
| James Wan | Executive Producer |
| Leigh Whannell | Executive Producer |
| Charlie Clouser | Original Music Composer |
| Alex Kavanagh | Costume Design |
| Anthony Ianni | Production Design |
| Peter Grundy | Art Direction |
| Brian Gedge | Director of Photography |
| Andrew Coutts | Editor |
| Liesl Deslauriers | Set Decoration |
| Stephanie Ingram | Key Hair Stylist |
| Colin Penman | Key Makeup Artist |
| François Dagenais | Prosthetic Makeup Artist |
| Kym Crepin | Production Manager |
| Steve Webb | First Assistant Director |
| David McLeod | First Assistant Director |
| David McAree | First Assistant Director |
| Rob Valeriote | Construction Coordinator |
| James R. Murray | Property Master |
| Dale Lennon | ADR Editor |
| Pat Cassin | Boom Operator |
| Gordon Chacra | Boom Operator |
| Moshe Saadon | Boom Operator |
| Jill Purdy | Dialogue Editor |
| Steve Baine | Foley |
| Katie Halliday | Sound Effects Editor |
| Richard Harkness | Sound Effects Editor |
| Keith Elliott | Sound Re-Recording Mixer |
| Andrew Tay | Sound Re-Recording Mixer |
| Mark Zsifkovits | Sound Re-Recording Mixer |
| Mark Gingras | Supervising Sound Editor |
| John Douglas Smith | Supervising Sound Editor |
| Ariel Joson | 3D Animator |
| Phil Dakin | 3D Artist |
| Doug Law | 3D Artist |
| Zachary Lowe | 3D Artist |
| Beryl Wu | 3D Artist |
| Rob Sanderson | Special Effects Supervisor |
| James Thomson | Visual Effects Coordinator |
| Tavia Charlton | Visual Effects Producer |
| Marc Whaley | Visual Effects Producer |
| Peter Denomme | Visual Effects Producer |
| Jon Campfens | Visual Effects Supervisor |
| Tom Turnbull | Visual Effects Supervisor |
| Wendy Whaley | Visual Effects Supervisor |
| Don Asido | Visual Effects Technical Director |
| Kevin Craine | Best Boy Electrician |
| Doug Reid | Best Boy Electrician |
| Michael Fylyshtan | Camera Operator |
| Mark Hroch | Steadicam Operator |
| Anton Van Rooyen | Second Unit Director of Photography |
| Patrick King | Dolly Grip |
| Craig Bulmer | Electrician |
| Steve Langer | Electrician |
| Desiree Lidon | Electrician |
| Neil Saito | Electrician |
| Paul Sheehan | Electrician |
| Marek Krawczyk | Electrician |
| Herb Reischl Jr. | Gaffer |
| Tim Lovell | Electrician |
| Robert McRae | Gaffer |
| Norman O'Halloran | Gaffer |
| Monty Montgomerie | Key Grip |
| Edward Lipscombe | Rigging Grip |
| Hugh Brule | Rigging Grip |
| Malcolm Nefsky | Rigging Grip |
| Brooke Palmer | Still Photographer |
| Mia Sturup | Assistant Costume Designer |
| Peter Armstrong | Digital Intermediate |
| Lee Hughes | Digital Intermediate |
| Motassem Younes | Digital Intermediate |
| Robert Doyle | First Assistant Editor |
| Patricia Joyes | Script Supervisor |
| Margaret Tanod | Script Supervisor |
| Elizabeth Tremblay | Script Supervisor |
| Erich Preston | Music Editor |
| Gregg Hoffman | Producer |
| Shelley Cook | Stunt Coordinator |
| Krista Bell | Stunt Double |
| E. Nova Zatzman | Stunts |
| Leigh Whannell | Original Film Writer |
| James Wan | Original Film Writer |
