 | Neve Campbell als Sidney Prescott |
 | Courteney Cox als Gale Weathers |
 | David Arquette als Dewey Riley |
 | Jerry O'Connell als Derek Feldman |
 | Timothy Olyphant als Mickey Altieri |
 | Jamie Kennedy als Randy Meeks |
 | Laurie Metcalf als Debbie Salt |
 | Elise Neal als Hallie McDaniel |
 | Sarah Michelle Gellar als Cici Cooper |
 | Liev Schreiber als Cotton Weary |
 | Jada Pinkett Smith als Maureen Evans |
 | Omar Epps als Phil Stevens |
 | Duane Martin als Joel Jones |
 | Lewis Arquette als Chief Hartley |
 | Rebecca Gayheart als Sorority Sister Lois |
 | Portia de Rossi als Sorority Sister Murphy |
 | Heather Graham als 'Stab' Casey |
 | Roger L. Jackson als Ghostface (voice) |
 | Joshua Jackson als Film Class Guy #1 |
 | Marisol Nichols als Dawnie |
 | Tori Spelling als Tori Spelling / 'Stab' Sidney |
 | Luke Wilson als 'Stab' Billy |
 | David Warner als Gus Gold |
 | Selma Blair als Cici's Friend on Phone |
 | Rasila Schroeder als Screaming Girl Up Aisle |
 | Peter Deming als Popcorn Boy |
| Molly Gross als Theater Girl #1 |
 | Rebecca McFarland als Theater Girl #2 |
 | Kevin Williamson als Cotton's Interviewer |
| Sandy Heddings als Girl in Dorm Hallway |
| Dave Allen Clark als Reporter Outside Theater |
| Joe Washington als Reporter #1 |
| Angie Dillard als Reporter #2 |
| John Patrick als Reporter #3 |
 | Craig Shoemaker als Artsy Teacher |
 | Walter Franks als Film Class Guy #2 |
| Nina Petronzio als Film Class Mopey Girl |
| Stephanie Belt als Reporter #4 |
| Richard Bruce Doughty als Reporter #5 |
| Cornelia Kiss als Coroner at Cici's House |
| Lucy Lin als ER Doctor |
 | Philip Pavel als Officer Andrews |
 | Nancy O'Dell als Tori's Interviewer |
| Greg Meiss als Zeus |
 | Adam Shankman als Ghost Dancer |
| Kris Andersson als Dancer |
| Carmen M. Chavez als Dancer |
 | Anne Fletcher als Dancer |
| Erik Hyler als Dancer |
 | Sebastian La Cause als Dancer |
| Lance MacDonald als Dancer |
| Laurie Sposit als Dancer |
| Ryan Lee Swanson als Dancer |
 | Sarah Christine Smith als Dancer |
| Jack Baun als Tackled Cell Phoner |
| Christopher Doyle als Officer Richards |
 | Jason Horgan als Fraternity Brother #1 |
| Daniel K. Arredondo als Fraternity Brother #2 |
| John Embry als Fraternity Brother #3 |
 | Corey Mendell Parker als Library Guy |
| Tim Hillman als Captain Down |
 | Mark Oliver als Reporter #6 |
 | Jennifer Weston als Reporter #7 |
| Shelly Benedict als Reporter #8 |
| Paulette Patterson als Usher Giving Out Costumes |
 | Wes Craven als Doctor (uncredited) |
 | Jason Trost als Audience Member (uncredited) |
 | Franco Castan als Student (uncredited) |
| Carrie Collins als College Student (uncredited) |
| Rodney L. James als Photographer (uncredited) |
 | Matthew Lillard als Guy at Party (uncredited) |
 | Deadra Moore als College Professor (uncredited) |
| Bob Ziembicki | Production Design |
| Keith G. Lewis | Set Costumer |
| Robyn Williams | Set Costumer |
| Amanda Zenil | Set Costumer |
| Ronit Ravich-Boss | Script Supervisor |
| Wes Craven | Director |
| Kevin Williamson | Characters |
| Kevin Williamson | Screenplay |
| Cathy Konrad | Producer |
| Marianne Maddalena | Producer |
| Marco Beltrami | Original Music Composer |
| Peter Deming | Director of Photography |
| Patrick Lussier | Editor |
| Lisa Beach | Casting |
| Ted Berner | Art Direction |
| Bob Kensinger | Set Decoration |
| Kathleen Detoro | Costume Design |
| Ron Trost | Special Effects Coordinator |
| Aimee Rousey | Art Department Coordinator |
| Dugg Kirkpatrick | Hair Department Head |
| Louisa V. Anthony | Key Hair Stylist |
| Richard Marin | Hairstylist |
| Carol Schwartz | Makeup Department Head |
| Jane Galli | Makeup Artist |
| Beth Katz | Makeup Artist |
| Judy Murdock | Makeup Artist |
| Daniel K. Arredondo | Associate Producer |
| Cary Granat | Co-Executive Producer |
| Daniel Lupi | Co-Producer |
| Nicholas Mastandrea | Associate Producer |
| Julie Plec | Associate Producer |
| Richard Potter | Co-Executive Producer |
| Andrew Rona | Co-Executive Producer |
| Harvey Weinstein | Executive Producer |
| Bob Weinstein | Executive Producer |
| Kevin Williamson | Executive Producer |
| Nicholas Mastandrea | First Assistant Director |
| Lucille OuYang | Second Assistant Director |
| Mark Balda | Construction Foreman |
| J.P. Jones | Property Master |
| Terry Kempf | Propmaker |
| Roy Dickson | Propmaker |
| Douglas Machala | Set Dresser |
| Martin Roy Mervel | Set Designer |
| G.W. Brown | Supervising ADR Editor |
| Andy D'Addario | Sound Re-Recording Mixer |
| Valerie Davidson | Sound Editor |
| David Diamond | Boom Operator |
| Kurt Nicholas Forshager | Sound Effects Editor |
| Howell Gibbens | Dialogue Editor |
| Jason King | Sound Editor |
| John Kwiatkowski | Dialogue Editor |
| Joe Milner | Sound Editor |
| Todd Toon | Supervising Sound Editor |
| Jennifer Badger | Stunt Double |
| Ted Barba | Stunts |
| Rick Barker | Stunts |
| Clay Boss | Stunts |
| Christine Brady | Stunts |
| Kurt Bryant | Stunts |
| Anthony Cecere | Stunt Coordinator |
| Mitchell Dean | Utility Stunts |
| Christopher Doyle | Stunts |
| Chris Durand | Stunts |
| Dane Farwell | Stunts |
| Michael Haynes | Stunts |
| Leslie Hoffman | Stunts |
| Melvin Jones | Stunts |
| Kelsee King-Devoreaux | Stunt Double |
| Barbara Anne Klein | Stunt Double |
| Hugh Aodh O'Brien | Utility Stunts |
| Allen Robinson | Stunts |
| Nancy Thurston | Stunts |
| Lee Waddell | Stunts |
| Sophia M. Crawford | Stunt Double |
| Waide R. Allen | Lighting Technician |
| Scott Browner | Camera Operator |
| Tim Collins | Rigging Grip |
| Dan Cornwall | Electrician |
| Jason Elias | Assistant Chief Lighting Technician |
| Flint Ellsworth | Lighting Technician |
| Kirk R. Gardner | Steadicam Operator |
| Ben Gaskin | Lighting Technician |
| Paul Hughen | Camera Operator |
| Brian Kinzey | Lighting Technician |
| Greg Peoples | Lighting Technician |
| Derick Pritchard | Lighting Technician |
| Scott Andrew Ressler | First Assistant Camera |
| Ron Sands | Lighting Technician |
| Katie Santore | Camera Loader |
| Peyton Skelton | Lighting Technician |
| Cliff Sperry | Dolly Grip |
| Rick A. West | Chief Lighting Technician |
| Kimberly Wright | Still Photographer |
| Greg D'Auria | Assistant Editor |
| Lisa Mozden | Assistant Editor |
| Michael Wertz | First Assistant Editor |
| Tim Hillman | Location Manager |
| Bill Abbott | Music Editor |
| Pete Anthony | Orchestrator |
| Ed Gerrard | Music Supervisor |
| Jon Kull | Orchestrator |
| Happy Walters | Music Supervisor |
| Geno Hart | Transportation Coordinator |
| Joe Cosentino | Transportation Captain |
| James W. Croke | Production Coordinator |
| Michele Carmel Long | Production Coordinator |
| Adam Shankman | Choreographer |
| Kelly A. Snyder | Production Accountant |
| Jerri Whiteman | Payroll Accountant |
| Sarah Katzman | Casting Assistant |
| Ajay Dass | Extras Casting |
| F. Scott Taylor | First Assistant Sound Editor |
| Gregg Barbanell | Foley Artist |
| Rich Green | Foley Artist |
| Laura Macias | Foley Artist |
| Scott Weber | Foley Mixer |
| Valerie Davidson | Foley Editor |
| Jason King | Foley Editor |
| Doc Kane | ADR Mixer |
| Barbara Harris | ADR Voice Casting |
| Rick Alexander | Sound Re-Recording Mixer |
| Richard D. Rogers | Sound Re-Recording Mixer |
| John Kurlander | Scoring Mixer |
