 | Ryan Reynolds als Young Damian |
 | Ben Kingsley als Damian |
 | Natalie Martinez als Madeline |
 | Matthew Goode als Albright |
 | Michelle Dockery als Claire |
 | Melora Hardin als Judy |
 | Victor Garber als Martin |
 | Sam Page als Carl |
 | Derek Luke als Anton |
 | Mariana Paola Vicente als Leah |
 | Jaynee-Lynne Kinchen als Anna |
 | Brendan McCarthy als Anton 2 |
 | Thomas Francis Murphy als Dr. Jensen |
 | Sandra Ellis Lafferty als Phyllis Jensen |
 | Emily Tremaine als Mallory |
 | Griff Furst als EMT #1 |
| Cedric Palmisano als EMT #2 |
 | Tom Waite als Ambulance Driver |
 | Douglas M. Griffin als Doctor X-Ray |
 | Marcus Lyle Brown als Lab Technician |
 | Teri Wyble als Andrea |
 | Gary Weeks als Chauffeur |
| Kristin Erickson als Gate Agent |
 | Dakota Buchanan als Dickish Cousin |
| Robert Harvey als Retirement Home Manager |
 | Jimmy Gonzales als Recovery Mercenary |
 | Jesica Ahlberg als Beautiful Girl #1 |
| Dacia Fernandez als Beautiful Girl #2 |
| Hannah Jelinovic als Beautiful Girl #3 |
| Ashley Laliberty als Beautiful Girl #4 |
| Anna Dudnik als Beautiful Girl #5 |
 | Big Freedia als Big Freedia |
| Antionique Price als Dancer #1 |
| Stephanie Bertrand als Dancer #2 |
| Shelby Skipper als Dancer #3 |
| Alvin Santana als Tap Dancer #1 |
| Rashod Singleton als Tap Dancer #2 |
| Keiton Crump als Tap Dancer #3 |
 | Clay Chamberlin als Hallway Lab Tech |
| Kate Ransome Wilcox als Coalition Volunteer |
| Julian Niccolini als Maitre'd |
| Mariah Quintana |
 | Steffie Grote als Jazz Club Waitress (uncredited) |
 | Claire McReynolds als Park Kid (uncredited) |
 | Lola Phillips als School Girl (uncredited) |
| Anne Speed als Nurse (uncredited) |
| Katherine Grace Yeaton als Cemetery Girl (uncredited) |
| Christopher Heskey als Medical Orderly (uncredited) |
| Dylan Lowe als Tony |
 | Ronn Surels als Mercenary (uncredited) |
| Tarsem Singh | Director |
| Àlex Pastor | Screenplay |
| David Pastor | Screenplay |
| Robert Duffy | Editor |
| Tom Foden | Production Design |
| Brendan Galvin | Director of Photography |
| Ram Bergman | Producer |
| Peter Schlessel | Producer |
| James D. Stern | Producer |
| Dudu Aram | Original Music Composer |
| Antonio Pinto | Original Music Composer |
| David Pomier | Line Producer |
| Venus Kanani | Casting |
| Mary Vernieu | Casting |
| Cameron Jewell | Co-Producer |
| Nikos Karamigios | Co-Producer |
| Josue Clotaire Fleurimond | Conceptual Design |
| Shay Cunliffe | Costume Design |
| Tim Beach | Art Direction |
| Cindy Carr | Set Decoration |
| Debra Schutt | Set Decoration |
| Jeremiah Hansen | Art Department Coordinator |
| Chuck Stringer | Construction Coordinator |
| Andree Fortier | Costume Supervisor |
| Toby Bronson | Set Costumer |
| Megan Richardson | Set Costumer |
| Richard Henderson | Music Editor |
| Rick Nelson | Music Editor |
| Robin Whittaker | Music Editor |
| John Houlihan | Music Supervisor |
| Jason Rhein | Music Director |
| Jean-Paul Chreky | Script Supervisor |
| Alexander B. Hill | Script Supervisor |
| Voni Hinkle | Hair Department Head |
| Carl G. Variste | Key Hair Stylist |
| Vivian Baker | Makeup Department Head |
| Stacy Kelly | Makeup Artist |
| Rick Nelson | Sound Recordist |
| Jason Rhein | Sound Recordist |
| Melissa Kennelly | Foley |
| Vince Nicastro | Foley |
| Robert L. Sephton | Sound Designer |
| Joe Lemola | Sound Effects Editor |
| Kevin O'Connell | Sound Re-Recording Mixer |
| Steven Ticknor | Sound Re-Recording Mixer |
| Robert L. Sephton | Supervising Sound Editor |
| Steven Ticknor | Supervising Sound Editor |
| Ryan Markley | 3D Artist |
| Rif Dagher | CG Supervisor |
| Raoul Bolognini | Visual Effects Producer |
| Kim Church | Visual Effects Producer |
| Adam Howard | Visual Effects Supervisor |
| Curt Miller | Visual Effects Supervisor |
| Ray McIntyre Jr. | Visual Effects Supervisor |
| Culley Bunker | Visual Effects Supervisor |
| David K. Nami | Special Effects Coordinator |
| Hilary Bronwyn Gayle | Additional Still Photographer |
| Patrick Longman | Aerial Camera |
| Corey Erwin | Best Boy Electric |
| Jerry M. Jacob | Camera Operator |
| Jody Miller | Steadicam Operator |
| Jaron Presant | Second Unit Director of Photography |
| Shawn Stone | Dolly Grip |
| Peter Bulavinetz | Dolly Grip |
| Bob Bates | Gaffer |
| Declan Ryan | Gaffer |
| Danny Brazen | Key Grip |
| Brendon Malone | Key Grip |
| Jim Grout | Lighting Technician |
| Jonathan Terpstra | Lighting Technician |
| Troy Anderson | Rigging Gaffer |
| Duane Cooper | Rigging Grip |
| Alan Markfield | Still Photographer |
| Billy Green | Additional Photography |
| Bryn Everett | Casting Assistant |
| Alexis Cadorette-Vigneau | Digital Intermediate |
| Carissa Clark | Digital Intermediate |
| Carl S.G. Moore | Digital Intermediate |
| Tony Bacigalupi | First Assistant Editor |
| Fulvio Valsangiacomo | Assistant Editor |
| Stephen LeBlanc | Location Manager |
| Al Cerullo | Pilot |
| Paul Barth | Pilot |
| Daniela Kriston | Researcher |
| Evan Trent | Script Editor |
| Diane Slattery | Unit Publicist |
| James Morioka | Dialogue Editor |
| Nico Soultanakis | Co-Producer |
| Lia Buman | Executive Producer |
| Julie Goldstein | Executive Producer |
| Eric VanArsdale | Stunts |
| Michael Ortiz | Stunts |
| Carl Anthony Nespoli | Stunts |
| Andy Abele | Stunts |
| John Bernecker | Stunt Double |
| Chris J. Fanguy | Stunt Double |
| Carlos Guity | Stunt Double |
| Theo Kypri | Stunt Double |
| Vanessa Motta | Stunt Double |
| Ronn Surels | Stunts |
| Brook Yeaton | Property Master |
| Eric Acsell | VFX Artist |
