 | Will Ferrell als Jackie Moon |
 | Woody Harrelson als Monix |
 | André 3000 als Clarence |
 | Maura Tierney als Lynn |
 | Andy Daly als Dick Pepperfield |
 | Will Arnett als Lou Redwood |
 | Andy Richter als Bobby Dee |
 | Rob Corddry als Kyle |
 | Matt Walsh als Father Pat the Ref |
 | Tim Meadows als Cornelius Banks |
 | David Koechner als Commissioner |
 | Jackie Earle Haley als Dukes |
 | DeRay Davis als Bee Bee Ellis |
 | Josh Braaten als Twiggy Munson |
 | Jay Phillips als Scootsie Double Day |
 | Peter Cornell als Vakidis |
 | Pat Kilbane als Petrelli |
 | Patti LaBelle als Jackie's Mom |
 | Collette Wolfe als Melinda |
 | Jason Sudeikis als Nacho Fan |
 | Kristen Wiig als Bear Handler |
 | Ellia English als Ms. Quincy |
 | Ian Roberts als Spurs Coach |
 | Phil Hendrie als Nets Coach |
 | Ed Helms als Turtleneck |
 | Brian Huskey als White Pants |
 | Paul Rust als Wheelchair Darren |
 | Charlyne Yi als Wheelchair Jody |
| Rashid Byrd als Tropics Player |
| Terrell Byrd als Tropics Player |
| Tyus Tillman als Tropics Player |
| Michael Westphal als Tropics Player |
| MaShae Alderman als Ball Girl |
| Briana Barran als Ball Girl |
| Karen Berg als Ball Girl |
| Charlie Gelbart als Ball Girl |
| Leigha Kingsley als Ball Girl |
| Kristin Pitts als Ball Girl |
| Jenica Robinson als Ball Girl |
| Erinn Selkis als Ball Girl |
| Sandy Sunshine als Ball Girl |
 | Steve Seagren als Losing Owner #1 |
 | Gil Glasgow als Losing Owner #2 |
| Noel Conlon als Man Being Hugged |
 | Scot Armstrong als Cameraman |
 | Steve Bannos als Cop at Jail |
| Anthony Burrell als Dancer |
| Dante Henderson als Dancer |
| Dan Domenech als Dancer |
 | Kate Luyben als Staci Moon (uncredited) |
 | Jerry Minor als Paul the DJ (uncredited) |
| Tiffany Michelle als Sarah (uncredited) |
| Charlie Koechner als Commissioner's Son (uncredited) |
| Gerard Averill als Gerard the Cop (uncredited) |
| Lyle Stevens als Duke's Buddy (uncredited) |
| Ralph Kampshoff als Indiana Pacers Owner (uncredited) |
 | Warren Sweeney als Winning Team Owner #1 (uncredited) |
| Grayson Boucher als Spirits Player #31 / Spurs Player #22 (uncredited) |
| Bruno Sandoval als Spurs Player #41 (uncredited) |
| Byron de Marse als Spurs Player (uncredited) |
 | Justen Naughton als Squires Player #31 (uncredited) |
 | James Markham Hall Jr. als Squires Basketball Player (uncredited) |
| David Sampen als Squires Basketball Player (uncredited) |
 | Kamal Moummad als Starting Point Guard (uncredited) |
| Quinn Hawking als Basketball player (uncredited) |
| Ryan C. Burney als Assist. Scoreboard Operator (uncredited) |
| Arne Starr als NY Nets On-Air Announcer (uncredited) |
 | Danny Mooney als Party Griller (uncredited) |
 | David E. Brown als Avid Tropics Fan (uncredited) |
| Theo Caesar als Tropics Fan (uncredited) |
| Sarah Elizabeth Dell als Tropics Fan (uncredited) |
 | Eddie Mariano als Tropics Fan (uncredited) |
| Lili Asvar als Fan (uncredited) |
| Scotty Atkins als Fan (uncredited) |
| Scott Cordts als Spectator (uncredited) |
| Laurie Curtis als Spectator (uncredited) |
 | Margaret Newborn als Spectator (uncredited) |
 | Gary Teague als Spectator (uncredited) |
 | Shawntay Dalon als Crowd Member (uncredited) |
 | Maria Zambrana als Basketball Game Watcher (uncredited) |
| Kent Alterman | Director |
| Scot Armstrong | Writer |
| Brian Avery | Stunts |
| Lauren Shuler Donner | Executive Producer |
| Shauna Duggins | Stunt Double |
| Theodore Shapiro | Music |
| Michael Aguilar | Executive Producer |
| Kent Alterman | Executive Producer |
| Cale Boyter | Executive Producer |
| Josh Church | Co-Producer |
| Victoria Cordova | Consulting Producer |
| Toby Emmerich | Executive Producer |
| David B. Householter | Executive Producer |
| Jimmy Miller | Producer |
| Shane Hurlbut | Director of Photography |
| Debra Neil-Fisher | Editor |
| Peter Teschner | Editor |
| Armen Ksajikian | Musician |
| Meegan E. Godfrey | Stunts |
| Allison Jones | Casting |
| Clayton Hartley | Production Design |
| Jim Gloster | Art Direction |
| Virginia Randolph-Weaver | Art Direction |
| Casey Hallenbeck | Set Decoration |
| Susan Matheson | Costume Design |
| Simone Almekias-Siegl | Makeup Artist |
| Steve Artmont | Key Makeup Artist |
| Bridget Cook | Key Hair Stylist |
| Nicole DeFrancesco | Hairstylist |
| Marianna Elias | Makeup Artist |
| Melissa Forney | Hairstylist |
| Cynthia Hernandez | Makeup Artist |
| Joann Kozloff | Makeup Artist |
| Jayne Laube | Makeup Artist |
| Lisa Layman | Makeup Artist |
| Elizabeth Rabe | Hairstylist |
| Darrell Redleaf-Fielder | Hairstylist |
| Marsha Shearrill | Makeup Artist |
| Judy Twine | Key Makeup Artist |
| Victoria Wood | Wigmaker |
| Adam Brandy | Makeup Artist |
| Kimberly Jones | Makeup Artist |
| Keith Sayer | Makeup Artist |
| Mark Robert Ellis | Second Unit Director |
| Courtenay Miles | First Assistant Director |
| Courtenay Miles | Second Assistant Director |
| Matt Rebenkoff | First Assistant Director |
| Paul Schneider | Second Second Assistant Director |
| Mark Trapenberg | Second Second Assistant Director |
| Ryan Cassidy | Set Dresser |
| Victor Mendez | Set Dresser |
| Charlie Campagna | Sound Recordist |
| Paul Timothy Carden | Dialogue Editor |
| Mark DeSimone | ADR Mixer |
| Victor Ray Ennis | Supervising Sound Editor |
| Victor Ray Ennis | Assistant Sound Editor |
| Nerses Gezalyan | Sound Mixer |
| Michael Hertlein | Dialogue Editor |
| Daniel S. Irwin | Dialogue Editor |
| Daniel R. Kerr | Sound Effects |
| Scott Millan | Sound Re-Recording Mixer |
| Glenn T. Morgan | Sound Effects |
| Mark Ormandy | Sound Effects |
| David Parker | Sound Re-Recording Mixer |
| Alan Rankin | Sound Designer |
| Art Rochester | Production Sound Mixer |
| Chip Sloan | ADR Recordist |
| Greg Steele | ADR Mixer |
| Mark P. Stoeckinger | Supervising Sound Editor |
| John C. Stuver | Dialogue Editor |
| Matthew E. Taylor | Additional Sound Re-Recordist |
| Jon Tendrich | Sound Mixer |
| Tim Walston | Sound Designer |
| Tim Walston | Sound Effects Editor |
| Kerry Dean Williams | ADR Supervisor |
| Dave Wilson | ADR Mixer |
| Greg Zimmerman | ADR Recordist |
| Jino Dinello | Special Effects |
| Roland Hathaway | Special Effects |
| Bruce Khteian | Special Effects |
| Bruce Minkus | Special Effects Coordinator |
| Todd 'Chin' Piepenbrok | Special Effects |
| Don Sustrich | Special Effects |
| Daniel Yeager | Special Effects Technician |
| Robert W. King | Special Effects |
| Joni Avery | Stunts |
| Scott Berst | Stunts |
| Erik Betts | Stunts |
| Stacey Carino | Stunts |
| Jacob Chambers | Stunts |
| Jeff Chumas | Stunts |
| Gilbert B. Combs | Stunts |
| Darrell Davis | Stunts |
| Kevin Derr | Stunt Double |
| Richard Epper | Stunts |
| Ian Eyre | Stunts |
| Mickey Giacomazzi | Stunts |
| Casey Hendershot | Stunts |
| Lisa Hoyle | Stunts |
| David Hugghins | Stunts |
| Terry Jackson | Stunts |
| Precious Jenkins | Stunt Double |
| Brett A. Jones | Stunts |
| Dorian Kingi | Stunts |
| Dan Lemieux | Stunt Double |
| Brian Machleit | Stunt Coordinator |
| Bob Marrocco | Stunts |
| Ed McDermott II | Stunt Driver |
| Derek Mears | Stunts |
| Randy Miller | Stunt Double |
| Sonja Munsterman | Stunt Double |
| Ryan O'Dell | Stunts |
| Anthony T. Pennello | Stunt Double |
| Damion Poitier | Stunts |
| Ming Qiu | Stunt Double |
| Kerry Rossall | Stunts |
| Buddy Sosthand | Stunts |
| Pete Turner | Stunts |
| Mark Aaron Wagner | Stunts |
| T.J. White | Stunts |
| Thom Williams | Stunts |
| Merritt Yohnka | Stunts |
| Layne Hannemann | Stunts |
