 | Alexa PenaVega als Carmen Cortez |
 | Daryl Sabara als Juni Cortez |
 | Antonio Banderas als Gregorio Cortez |
 | Carla Gugino als Ingrid Cortez |
 | Steve Buscemi als Romero |
 | Mike Judge als Donnagon |
 | Danny Trejo als Machete |
 | Cheech Marin als Felix Gumm |
 | Matt O'Leary als Gary Giggles |
 | Emily Osment als Gerti Giggles |
 | Ricardo Montalban als Grandfather |
 | Holland Taylor als Grandmother |
 | Alan Cumming als Fegan Floop |
 | Tony Shalhoub als Alexander Minion |
 | Taylor Momsen als President's Daughter |
 | Christopher McDonald als President of the USA |
 | Bill Paxton als Dinky Winks |
 | Dale Dudley als Head Magna Man |
 | Troy Robinson als Magna Man / Waiter |
 | Ron Hayden als Main Secret Agent |
| Brian Thornton als Secret Agent #2 |
| Mark Turner als Secret Agent #3 |
| Jasmine Marin als Spy Girl |
 | Angela Lanza als Park Public Relations |
| Felix Sabates als Test Family |
| Lynda Sabates als Test Family |
| Alexandra Sabates als Test Family |
| Victoria Sabates als Test Family |
| Robert Rodriguez | Director |
| Bob Weinstein | Executive Producer |
| Robert Rodriguez | Director of Photography |
| Robert Rodriguez | Editor |
| John Debney | Original Music Composer |
| Robert Rodriguez | Producer |
| Harvey Weinstein | Executive Producer |
| Robert Rodriguez | Screenplay |
| Elizabeth Avellan | Producer |
| Robert Rodriguez | Original Music Composer |
| Robert Rodriguez | Production Design |
| Andy McCauley | Carpenter |
| Ronn Basquette | Set Designer |
| Christopher Stull | Set Dresser |
| Robyn Jacobs | Painter |
| Graciela Mazón | Costume Design |
| Charles Seale | Carpenter |
| Tom Christopher | Set Dresser |
| David Wilt | Construction Foreman |
| Ed Callahan | Foley Editor |
| Ronnie White | Carpenter |
| Caylah Eddleblute | Assistant Property Master |
| Alan R. Serotta | Construction Foreman |
| Dean Beville | Supervising Sound Editor |
| Mike Chock | Sound Effects Editor |
| Robert Rodriguez | Sound Re-Recording Mixer |
| Charles Ewing Smith | Dialogue Editor |
| Bart Brown | Set Dresser |
| David Hack | Leadman |
| Jane Nerlinger Evans | Executive In Charge Of Production |
| Bill Scott | Unit Production Manager |
| Bill Dunagin | Carpenter |
| Joe McCusker | Construction Coordinator |
| John Pritchett | Production Sound Mixer |
| Robert Rodriguez | Sound Effects Editor |
| Bill Scott | Line Producer |
| Rodney Brown | Construction Foreman |
| Joe D. Mack | Prop Maker |
| Jamie Hardt | Assistant Sound Editor |
| Mary Vernieu | Casting |
| Phillip Williams | Carpenter |
| John Frick | Art Direction |
| Randy Severs | Carpenter |
| Shane Patrick | Set Dresser |
| William Jacobs | Sound Effects Editor |
| Peter O'Brien | Sound Effects Editor |
| Ed Vega | Supervising Art Director |
| Steve Joyner | Property Master |
| Michael Semanick | Sound Re-Recording Mixer |
| Jeanette Scott | Set Decoration |
| Brian Bettwy | First Assistant Director |
| Vincent Palmo Jr. | Second Assistant Director |
| April Crump | Set Dresser |
| J.P. Barrow | Carpenter |
| Debbie Cortez Haber | Art Department Assistant |
| Ronald Perkins | Construction Foreman |
| Jennifer Long | Set Decoration Buyer |
| Ana Martínez | Art Department Coordinator |
| David M. Roberts | Boom Operator |
| Sergio Reyes | Sound Re-Recording Mixer |
| Brian McNulty | Post Production Supervisor |
| Craig Byrom | Carpenter |
| Mark Hanks | Set Dresser |
| Troy Robinson | Stunts |
| Steve M. Davison | Stunts |
| Jeffrey J. Dashnaw | Stunt Coordinator |
| Erik Rondell | Stunts |
| Katie Boggs | Stunts |
| Guy Bews | Stunts |
| Tony Lee Boggs | Stunts |
| Troy Brown | Stunts |
| Chad Dashnaw | Stunts |
| Nicholas Dashnaw | Stunts |
| J.J. Dashnaw | Stunts |
| Peter Epstein | Stunts |
| Dick Hancock | Stunts |
| Cassidy Vick Hice | Stunts |
| Dylan Hice | Stunts |
| Dino Dos Santos | Stunt Double |
| Tracy Keehn-Dashnaw | Stunts |
| Freddie Hice | Stunts |
| Lin Oeding | Stunts |
| Víctor Quintero | Stunts |
| Tim Trella | Stunts |
| Jeff Schwan | Stunts |
| Krizia Vega | Stunts |
| Joe Bucaro III | Stunts |
