 | Jonah Hill als Seth |
 | Michael Cera als Evan |
 | Christopher Mintz-Plasse als Fogell |
 | Bill Hader als Officer Slater |
 | Seth Rogen als Officer Michaels |
 | Martha MacIsaac als Becca |
 | Emma Stone als Jules |
 | Aviva Baumann als Nicola |
 | Joe Lo Truglio als Francis the Driver |
 | Kevin Corrigan als Mark |
 | Clement Blake als Homeless Guy |
 | Erica Vittina Phillips als Liquor Store Cashier |
 | Joe Nuñez als Liquor Store Clerk |
 | Dave Franco als Greg the Soccer Player |
 | Marcella Lentz-Pope als Gaby |
 | Scott Gerbacia als Jesse |
 | Laura Seay als Shirley |
| Roger Iwami als Miroki |
| Clint Mabry als Prosthetic Leg Kid |
 | Stacy Edwards als Evan's Mom |
| Mark Rogen als Father with Bat |
 | Charlie Hartsock als Good Shopper Cashier |
 | Dona Hardy als Old Lady |
 | Charley Rossman als Good Shopper Security |
 | Carla Gallo als Period Blood Girl |
 | Ben Best als Quince Danbury |
 | Jody Hill als Tut Long John Silver |
 | Kevin Breznahan als Patrick Manchester |
 | David Krumholtz als Benji Austin |
 | Mousa Kraish als Billy Baybridge |
| Nicholas Jasenovec als Coffee Fairmount |
 | Martin Starr als James Masselin |
 | Keith Loneker als Wild Bill Cherry |
 | Matthew McKane als Kane Cloverdale |
 | Lauren Miller als Scarlett Brighton |
| Peter Salett als Tiger Greendragon |
 | Rakefet Abergel als Muffin Selby |
 | Brooke Dillman als Mrs. Hayworth |
 | Michael Naughton als Gym Teacher |
 | Steve Bannos als Math Teacher |
| Casey Margolis als Young Seth |
 | Laura Marano als Young Becca |
 | Matthew Bass als Vagtastic Voyager |
 | Aurora Snow als Vagtastic Voyage Girl #1 |
 | Jenna Haze als Vagtastic Voyage Girl #2 |
| Ted Haigh als Bartender |
| Michael Fennessey als Bus Driver |
 | Brian Huskey als Elementary Principal |
 | Clark Duke als Party Teenager #1 |
 | Stephen Borrello IV als Party Teenager #2 |
| Naathan Phan als Party Teenager #3 |
 | Pamella D'Pella als Teacher |
 | Danny McBride als Buddy at Party (uncredited) |
 | Cortney Palm als Party Guest (uncredited) |
| William Kerr | Editor |
| Shauna Robertson | Producer |
| Seth Rogen | Executive Producer |
| Russ T. Alsobrook | Director of Photography |
| Judd Apatow | Producer |
| Evan Goldberg | Executive Producer |
| Greg Mottola | Director |
| Chris L. Spellman | Production Design |
| Allison Jones | Casting |
| Gerald Sullivan | Art Direction |
| Dara Weintraub | Co-Producer |
| Bob Kensinger | Set Decoration |
| Evan Goldberg | Writer |
| Seth Rogen | Writer |
| Debra McGuire | Costume Design |
| Lyle Workman | Original Music Composer |
| Dara Weintraub | Unit Production Manager |
| Tim Trella | Stunt Coordinator |
| Kenny Alexander | Stunts |
| Scott Robertson | First Assistant Director |
| Steven F. Beaupre | Second Assistant Director |
| Christa Vausbinder | Production Supervisor |
| Michelle Spears | Property Master |
| Ronit Ravich-Boss | Script Supervisor |
| Steven H. Smith | Camera Operator |
| Jason Garcia | First Assistant Camera |
| Rigney Sackley | Second Assistant Camera |
| Jerome Fauci | Steadicam Operator |
| Jerome Fauci | "B" Camera Operator |
| Timothy James Kane | First Assistant "B" Camera |
| Betty Chow | Second Assistant "B" Camera |
| Nick Theodorakis | Digital Imaging Technician |
| Mary Walbridge | Costume Supervisor |
| Michael A. Russell | Key Costumer |
| Kimberly Greene | Makeup Department Head |
| Lana Horochowski | Key Makeup Artist |
| Maggie Fung | Makeup Artist |
| Robert Hall | Special Effects Makeup Artist |
| Melissa Yonkey | Hair Department Head |
| Merribelle Anderson | Key Hair Stylist |
| Dena Fayne | Hairstylist |
| Chris Napolitano | Chief Lighting Technician |
| Ron Alexus | Assistant Chief Lighting Technician |
| T. Daniel Scaringi | Key Grip |
| Robert Chinello | Best Boy Grip |
| Paul E. Sutton | Dolly Grip |
| Michael Wahl | Dolly Grip |
| Harrison D. Marsh | Production Sound Mixer |
| Tom Fox | Boom Operator |
| Jay M. Huntoon | Video Assist Operator |
| Bob Stoker | Special Effects Coordinator |
| Christine Bonnem | Location Manager |
| Sara Scarritt | Production Coordinator |
| Edward Allen | Production Accountant |
| Alicia Maccarone | Set Designer |
| Natalie Richards | Set Designer |
| Thierry Labbe | Leadman |
| Ted Haigh | Graphic Designer |
| Darryl Henley | Storyboard Artist |
| Kat Wilson | Art Department Coordinator |
| Kim Richey | Assistant Property Master |
| Karen Higgins | Construction Coordinator |
| Kym Langlie | Unit Publicist |
| Melissa Moseley | Still Photographer |
| Dorian Frankel | Casting Associate |
| Nancy A. Flint | Studio Teacher |
| Michael Menapace | Transportation Captain |
| James D. D'Amico | Transportation Co-Captain |
| Michael L. Sale | Additional Editor |
| Dov Samuel | First Assistant Editor |
| George H. Anderson | Supervising Sound Editor |
| Cherie Tamai | Assistant Sound Editor |
| Ann Ducommun | Assistant Sound Editor |
| James Matheny | Dialogue Editor |
| Larry Kemp | Dialogue Editor |
| Cindy Marty | Sound Effects Editor |
| Tammy Fearing | Supervising ADR Editor |
| Joe Schiff | Foley Editor |
| Pamela Kahn | Foley Artist |
| Vincent Guisetti | Foley Artist |
| Kyle Rochlin | Foley Mixer |
| Jonathan Karp | Music Editor |
| Chris Fogel | Scoring Mixer |
| John Persichetti | Digital Colorist |
| Mo Henry | Negative Cutter |
| Anita Hart | Stunt Driver |
| Buddy Joe Hooker | Stunts |
| Mic Rodgers | Stunts |
| Michael Runyard | Stunts |
| Todd Warren | Stunts |
| Cody Gill | Stunts |
| Kevin Beard | Stunt Double |
| Tony Donno | Stunt Double |
| David Castillo | Stunt Driver |
| Tom Elliott | Stunts |
| Thomas Robinson Harper | Stunts |
| Matt Leonard | Stunts |
| Rex Reddick | Stunt Double |
| Dina L. Margolin | Stunt Double |
| Richard C. Taylor | Stunt Driver |
