 | Christopher Thornton als 'Delicious' Dean O'Dwyer |
 | Mark Ruffalo als Father Joe |
 | Juliette Lewis als Ariel Lee |
 | Orlando Bloom als The Stain |
 | Laura Linney als Nina Hogue |
 | Noah Emmerich als Rene Faubacher |
 | James Karen als Father Rohn |
 | John Carroll Lynch als Evangelist Carroll |
 | Robert Wisdom als Prendell |
 | Dov Tiefenbach als Oogie |
 | Niko Nicotera als Rasha |
 | Deantoni Parks als Chuck |
 | Stephen Mendillo als Angry Drunk Harv |
| Sandra Seacat als Mrs. Matilda |
 | Shaun Duke als Dr. Zaheedi |
 | Allie Smith als Rene's Wife |
 | Daniel Escobar als Hector |
 | Jason Hiller als Church Organist |
 | Tara Stewart als Lupus Woman |
 | George W. Scott als Jerry |
 | Nathan Wetherington als Bartender |
 | Michael Anthony Spady als Mute Brute |
 | Lydia Blanco Garza als Boy's Mother |
 | Hiep Thi Le als Female Voluteer |
 | Louis Mendoza als Maria Leceta |
 | Mariko Denda als Young Chinese Girl |
 | Willie Macc als Willie the Shill |
 | Valeri Ross als Judge |
 | Rick Peters als Prosecuting Attorney Peters |
 | Cari Champion als Internet Journalist |
 | Brian Goodman als C.O. Jacko |
 | Bradley Wayne James als DJ Maestro Sonica |
 | Owen Conway als Counter Guy |
 | Sylvia St James als Homeless Woman |
 | Laurel Astri als Laura |
| Karen Jin Beck als DJ Shy (uncredited) |
 | Milissa Sears als Fan #3 (as Milissa Skoro) |
 | Kelli Barksdale als Teddy Bear Girl (uncredited) |
 | Diana Terranova als Brittany (uncredited) |
 | Bonnie McNeil als Mrs. Zaheedi |
| Alex Aves als Nina’s Assistant |
| Anne Wile als Old Lady |
 | Martin Charles Warner als Older Man |
 | Tonita Castro als Desperate Mexican Woman |
 | Marnie Alexenburg als Paramedic #1 |
| Timothy McNeil als Ryan Webster |
| Oscar Best als Security Guard on Bullhorn |
 | Kaleti Williams als Guard #1 |
 | Tracey Buckner als Roadie |
| Ray Auxias als Jamal - Guy Who Jumps on Stage (uncredited) |
| Mark Ruffalo | Director |
| Pete Beaudreau | Editor |
| Christopher Thornton | Writer |
| Mark Ruffalo | Producer |
| Christopher Norr | Director of Photography |
| Gina Resnick | Executive Producer |
| Christopher Thornton | Producer |
| Heidi Levitt | Casting |
| Wednesday Standley | Second Unit Director |
| Andrea Sperling | Producer |
| Michelle Torres | Art Department Coordinator |
| Scott Prisand | Producer |
| Marc Bell | Executive Producer |
| Barry Habib | Executive Producer |
| Toni Habib | Executive Producer |
| Dean M. Leavitt | Executive Producer |
| Joanne Jacobsen | Executive Producer |
| Michael Roban | Executive Producer |
| Robert Stein | Executive Producer |
| Marcelo Paladini | Executive Producer |
| Mike Crawford | Line Producer |
| Chase Mishkin | Associate Producer |
| Jeff Davis | Co-Producer |
| Tom Pellegrini | Co-Producer |
| Andrew Renzi | Co-Producer |
| Israel Wolfson | Co-Producer |
| Matt Weaver | Producer |
| The Besnard Lakes | Music |
| Michael Grasley | Production Design |
| Michael Hersey | Art Direction |
| Gregory S. Webb | Set Decoration |
| Erin Benach | Costume Designer |
| Mandy Danielle Benton | Assistant Makeup Artist |
| Raqueli Dahan | Assistant Makeup Artist |
| Kelcey Fry | Assistant Makeup Artist |
| Michelle Bühler | Makeup Department Head |
| Lori Guidroz | Hair Department Head |
| Sheila Cyphers-Leake | Additional Hairstylist |
| Roxxi Dott | Key Hair Stylist |
| Martina Kohl | Key Makeup Artist |
| Michael Mosher | Special Effects Makeup Artist |
| Thomas E. Surprenant | Special Effects Makeup Artist |
| Brian Buckland | Production Manager |
| Louise Runge | Post Production Supervisor |
| Matt Miller | Additional Second Assistant Director |
| Benjamin Schneider | Second Assistant Director |
| Michael Whitecar | Additional Second Assistant Director |
| Chad Rosen | First Assistant Director |
| Felisha Grice Pedersen | Second Second Assistant Director |
| Douglas W. Randall | Special Effects Coordinator |
| Dylan Hucklesby | Visual Effects |
| Tim Schmidt | Visual Effects |
| Mark Intravartolo | Visual Effects |
| Kit Lubold | Visual Effects |
| Salar Ghajar | Stunt Double |
| Ben Hernandez Bray | Stunts |
| Anthony Molinari | Stunt Coordinator |
| Michael Baird | Sound Designer |
| Robert Dehn | Sound Supervisor |
| James Dehr | Sound |
| Brent Findley | Sound Effects Editor |
| Dennis Grzesik | Sound Mixer |
| Richard Kitting | Sound Mixer |
| Jonathan Wales | Sound Mixer |
| Jason Gaya | ADR Mixer |
| Corey J. Grasso | ADR Mixer |
| Bryce Meehan | ADR Recordist |
| Chris White | ADR Recordist |
| Angela Hemingway | ADR Editor |
| Angela Hemingway | Dialogue Editor |
| Zach Michaelis | Foley Mixer |
| Tula Snoeck | Boom Operator |
| Vicki O'Reilly Vandegrift | Foley Artist |
| Jonathan Pendergrass | Foley Editor |
| Steven Iba | Assistant Sound Editor |
| David Fincher | Thanks |
| Kanica Suy | Thanks |
| David Sweeney | Thanks |
| Scott Ruffalo | In Memory Of |
| Chris Aguilar Garcia | Producer's Assistant |
| Amy Agzarian | Production Accountant |
| Gina Amador | Post Production Accountant |
| Keith Anthony | Loop Group Coordinator |
| Edward Baney | Set Production Assistant |
| Jorge Arce | Catering |
| Steve Baruch | Set Medic |
| Roger Aaron Brown | Loop Group Coordinator |
| James Burkhammer | Other |
| Nick Darmstaedter | Set Production Assistant |
| Gabriel Dell Jr. | Stand In |
| James Doogan | Technical Advisor |
| Terri Douglas | Loop Group Coordinator |
| Minnie Duerr | Production Accountant |
| Hugo G. Gordillo | Schedule Coordinator |
| Fred M. Hahn | Health and Safety |
| Leigh Huser | Producer's Assistant |
| Marabina Jaimes | Loop Group Coordinator |
| Samuel Kleist | Craft Service |
| Heidi Kohler | Producer's Assistant |
| Donna Lynn Leavy | Loop Group Coordinator |
| Mark R. Lindsay | Other |
| Nery Arnold Lopez | Assistant Chef |
| Chris Lun | Set Medic |
| Trevor Nichols | Set Medic |
| Crystal Maldonado | Assistant Craft Service |
| Meg Marchand | Key Set Production Assistant |
| Chris Mathews | Assistant Craft Service |
| Don McClanahan | Health and Safety |
| Cord McConnell | Production Office Assistant |
| Luis Meza | Catering |
| Shawn Morse | Set Production Assistant |
| Erica Neilsen | Production Office Assistant |
| Jonathan Nichols-Navarro | Loop Group Coordinator |
| Bola Ogun | Set Production Assistant |
| Miguel Pimentel | Chef |
| Gui Sauder Pinto | Set Production Assistant |
| Irwin M. Rappaport | Legal Services |
| Freddie Rojas | Set Production Assistant |
| Ellen Rosentreter | Set Production Assistant |
| Kimberly Russell | Loop Group Coordinator |
| Joan Scheckel | Other |
| Dennis Singletary | Loop Group Coordinator |
| Rob Spence | Production Coordinator |
| Emily Sperling | Intern |
| Gregg Spiegelman | Set Medic |
| Wednesday Standley | Assistant Director |
| David Sturdy | Health and Safety |
| Heidi Sulzman | Loop Group Coordinator |
| Didi Tokova | First Assistant Accountant |
| Mike Tsucalas | Set Production Assistant |
| Salvador Verduzco | Assistant Craft Service |
| Paul Volpe | Assistant Craft Service |
| Chris Whitaker | Set Medic |
| Sean Whittaker | Set Medic |
| Walter Wiggins | Assistant Craft Service |
| Cortney L. Wilson | Other |
| Sarah Carleton | Executive Producer's Assistant |
| Ken Coon | Layout |
| Glenn D. Feig | Legal Services |
| Malorie Folino | Production Assistant |
| Marc C. Geschwind | Extras Casting Coordinator |
| Charlene McAnoy | Stand In |
| Jeff Foxworth | Music |
| Brad Hamilton | Music Consultant |
| The Ontic | Music |
| Howard Paar | Music Supervisor |
| Deantoni Parks | Additional Music |
| Rye Randa | Music |
| Marcus Ranti | Music Consultant |
| Micki Stern | Music Coordinator |
| Jason Turbin | Music Consultant |
| Heather Askew | Script Supervisor |
| Ed Adams | Picture Car Coordinator |
| Tony Ruiz | Transportation Coordinator |
| Jay Norof | Transportation Captain |
| Domingo Bustamante | Driver |
| Brian Eastveld | Driver |
| Frankie Gearhart | Driver |
| Steve Gentry | Driver |
| Kelly Harkess | Driver |
| J.F. Jones | Driver |
| Jose Lopez | Driver |
| Calvin McDowell | Driver |
| John Ober | Driver |
| Andrew Sarvis | Driver |
| Terry Smith | Driver |
| Donald Tillman | Driver |
| Matt Voytish | Driver |
| Darren Wingate | Driver |
| Caroline Applegarth | Art Department Assistant |
| Chris Cafferty | Swing |
| Àlex Cano | Carpenter |
| Chris Coles | Swing |
| Steve Coover | Leadman |
| Alexander Delgado | Property Buyer |
| Malili Dib | Assistant Production Design |
| Jason Filipovi | Graphic Designer |
| Gabby Glasser | Art Department Trainee |
| Alexi Gomez | Property Buyer |
| Maxilino Gonzalez | Construction Coordinator |
| Dylan Hall | Swing |
| Scott Hameister | Art Department Assistant |
| Sahara Hite | Property Buyer |
| Abraham Jimenez | Art Department Trainee |
| John King | Swing |
| Megan Kristen Lane | Property Master |
| John Londono | Swing |
| Stephen Lynd | On Set Dresser |
| Timberly Matonic | Props |
| T.J. McCall | Scenic Artist |
| Miles Michael | Swing |
| Vladimir E. Morales | Scenic Artist |
| David Nicholson | Property Master |
| Chantal Pershing | Swing |
| Douglas W. Randall | Property Master |
| William Reges | Property Master |
| Jefry Shebroe | Assistant Property Master |
| Taylor Van Byssum | Swing |
| Kent Alexander | Rigging Grip |
| Robby Baumgartner | Camera Operator |
| Jean-Philippe Belliard | Lighting Technician |
| Steve Brewer | Grip |
| Darwin Montana Browne | Key Grip |
| Nelson Castillo | Electrician |
| Cheli Clayton | First Assistant "C" Camera |
| Mark Colicci | First Assistant "C" Camera |
| Brian Crane | Rigging Gaffer |
| Jon Delgado | Camera Operator |
| Kristen Eccker | Second Assistant "B" Camera |
| Erik Emerson | First Assistant "B" Camera |
| Fernando Espiritusanto | Lighting Technician |
| Walter Glover II | Electrician |
| Ismael 'Izzy' Gonzalez | Electrician |
| Augustus Gordon | Electrician |
| David Gottlieb | Lighting Technician |
| Jesse Gregson | Lighting Technician |
| Lisa Guerriero | Second Assistant "C" Camera |
| David Haeussler | Techno Crane Operator |
| David Hagadorn | Best Boy Electric |
| Jake Hansen | Camera Production Assistant |
| Sean Harris | Video Report |
| Brian Harvick | Grip |
| Billy Heath | Grip |
| House | Rigging Grip |
| Michael Kennedy | Lighting Technician |
| Nicholas Klein | Grip |
| L.K.f. | Additional Second Assistant Camera |
| Jeremy Launais | Gaffer |
| James R. Lay | Techno Crane Operator |
| Steve Lazarus | Electrician |
| Chris Leidholdt | Rigging Grip |
| Jim Leidholdt | Dolly Grip |
| Jay Levy | First Assistant "A" Camera |
| Kurt S. Levy | Camera Production Assistant |
| Sam Liotta | Best Boy Grip |
| Luis Lopez DeVictoria | Grip |
| Glen Magers | Lighting Technician |
| Abraham Martinez | Additional Camera |
| Shawn Maurer | Additional Photography |
| Eduardo Enrique Mayén | Additional Camera |
| Scott McGeo | Best Boy Grip |
| Jesse Mex | Grip |
| Yuji Nakaza | Lighting Technician |
| O | Second Assistant "D" Camera |
| Pat O'Mara | Grip |
| George A. Olson Jr. | Additional First Assistant Camera |
| Mark Rappoport | Lighting Technician |
| Felix Rivera | Lighting Technician |
| Kenny Solomon | Electrician |
| Erne Soto | Grip |
| Tim Speed | Electrician |
| Jennifer Stuart | Second Assistant "A" Camera |
| Gregg Thompson | Dolly Grip |
| Noah Thomson | Loader |
| Eric Tramp | Camera Operator |
| Sam Urdank | Still Photographer |
| Mike Visencio | Electrician |
| Darryl Walthall | Electrician |
| Jerald L. Wilson | Electrician |
| William D. Wynn | Grip |
| Terri Douglas | ADR Voice Casting |
| Lisa Essary | Casting Associate |
| Lauren Fernandes | Casting Associate |
| Rich King | Extras Casting |
| Shaunessy James Quinn | Extras Casting Assistant |
| Dionne Barens | Set Costumer |
| Josh Christensen | Set Costumer |
| Michele Dunn | Costume Supervisor |
| Lindsey Kear | Assistant Costume Designer |
| Christopher Koelsch | Set Costumer |
| Nina Lenders | Costume Assistant |
| Caroline Patterson | Key Set Costumer |
| Maritza Vallejos Pellegrino | Set Costumer |
| Ivette Silberman | Set Costumer |
| Azalia Snail | Set Costumer |
| Linda Thayer | Set Costumer |
| Alicya Blake | Wardrobe Assistant |
| Donnie Creighton | Digital Intermediate Producer |
| Doug Delaney | Digital Intermediate Colorist |
| Tracey Grimes | Other |
| Samantha Housman | Post Production Coordinator |
| Matthew W. Johnson | Digital Intermediate Editor |
| Sean Lawrence | Colorist |
| Lance Spindler | Color Timer |
| Jennifer M. Taylor | Assistant Editor |
| Alishe Beardeaux | Post Production Assistant |
| Jenny Caloca | Assistant Location Manager |
| Alexandra McCloud-Gibson | Location Scout |
| Rony Shino | Location Scout |
| Peter Wulff | Location Manager |
| Robert Clotworthy | Loop Group Coordinator |
