 | Ewan McGregor als Renton |
 | Jonny Lee Miller als Simon |
 | Ewen Bremner als Spud |
 | Robert Carlyle als Begbie / Begbie's Father |
 | Anjela Nedyalkova als Veronika |
 | Shirley Henderson als Gail |
 | Kelly Macdonald als Diane |
 | Pauline Turner als June |
 | Scot Greenan als Frank Junior |
 | James Cosmo als Renton's Father |
 | Irvine Welsh als Mikey Forrester |
 | Logan Gillies als Simon (aged 9) |
 | Ben Skelton als Renton (aged 9) |
| Aiden Haggarty als Spud (aged 9) |
| Daniel Smith als Begbie (aged 9) |
 | Elijah Wolf als Tommy (aged 9) |
 | Steven Robertson als Stoddart |
| John Kazek als Tom (Rehab Group) |
| Charlie Hardie als Fergus (aged 9) |
| Scott Aitken als Farmer |
 | Gordon Kennedy als Tulloch |
 | Tereza Duskova als Tourism Girl |
| Elek Kish als Dozo |
 | Lewis Gribben als Dealer |
| Dominic Maccoll als Dealer |
| Calum Verrecchia als Dealer |
| Simon Weir als Jailhouse |
 | Bradley Welsh als Doyle |
 | Katie Leung als Nurse |
| Thierry Mabonga als Security Officer Wilson |
 | Atta Yaqub als Medical Student |
| Christopher Douglas als Chris the Oracle |
 | James McElvar als Simon (aged 20) |
 | Connor McIndoe als Renton (aged 20) |
 | Bryan Quinn als Man in Music Video |
| Ged Hanley als Social Club Band |
| Neil Thomson als Social Club Band |
| Margaret Davies als Social Club Singer |
| Alex Jackson als Social Club Singer |
 | Tom Urie als Big Bear |
| Phil Coppola als Boxing Instructor |
 | John Bell als Spud (aged 20) |
 | Kyle Fitzpatrick als Fergus |
 | Eileen Nicholas als Renton's Mother |
 | Michael Shaw als Tommy (aged 20) |
 | Kevin McKidd als Tommy |
| Lauren Lamb als Baby Dawn |
| Devon Lamb als Baby Dawn |
 | Amy Manson als Woman in Club |
| Russell Dunsmore als Hard Guy Driver |
 | Nebli Basani als Hardman |
| Edyta Szewczyk als Girl in Sauna |
 | Fiori Miari als Girl in Sauna |
 | Pauline Lynch als Lizzy |
 | Christopher Mullen als Begbie (aged 20) |
| Hamish Haggerty als Young Renton |
| Daniel Jackson als Young Begbie |
 | Svetla Yancheva als Veronika's Mother |
| Emil Bonev als Veronika's Son |
 | Blair Flucker als Club Patron (uncredited) |
 | Adam James Johnston als Club Patron (uncredited) |
| Danny Boyle | Director |
| Irvine Welsh | Novel |
| John Hodge | Adaptation |
| John Hodge | Screenplay |
| Bernard Bellew | Producer |
| Danny Boyle | Producer |
| Christian Colson | Producer |
| Andrew Macdonald | Producer |
| Jon Harris | Editor |
| Gail Stevens | Casting |
| Mark Tildesley | Production Design |
| Adam Squires | Art Direction |
| Véronique Melery | Set Decoration |
| Stephen Noble | Costume Design |
| Chris Lyons | Facial Setup Artist |
| Claire Campbell | Production Manager |
| Brendan Houghton | Storyboard |
| Katie Johnston | Painter |
| Elo Soode | Conceptual Design |
| Glenn Freemantle | Sound Designer |
| Glenn Freemantle | Supervising Sound Editor |
| Colin Gregory | First Assistant Sound Editor |
| Colin Nicolson | Production Sound Mixer |
| Rebecca Farhall | Casting Associate |
| Martin Auld | Driver |
| Russell D. Equi | Transportation Captain |
| Andy Finnie | Driver |
| Stuart W. Fraser | Driver |
| Neil Cairns | Production Accountant |
| Amy MacIlraith | Transportation Coordinator |
| Sylvia Parker | Script Supervisor |
| Anthony Dod Mantle | Director of Photography |
| Lee Gren | Tattoo Designer |
| Kamen Glover | Hairstylist |
| Heather Manson | Hairstylist |
| Ivana Primorac | Hair Designer |
| Thomas Neivelt | Gaffer |
| Jaap Buitendijk | Still Photographer |
| Graeme Hunter | Still Photographer |
| Jim Elliott | Armorer |
| Niv Adiri | Sound Designer |
| Ben Barker | Sound Designer |
| Danny Freemantle | Sound Effects Editor |
| Chey Anich | Stunt Double |
| Robert Hladik | Stunt Driver |
| Erol Mehmet | Stunts |
| Lee Moulton-Davies | Stunt Double |
| Rob Pavey | Stunts |
| Julian Spencer | Fight Choreographer |
| Rick Smith | Original Music Composer |
| Scott Hunter | Camera Trainee |
| Elo Soode | Concept Artist |
| Niv Adiri | Sound Re-Recording Mixer |
| Mark Appleby | ADR Mixer |
| Linda Brenon | Foley Editor |
| Peter Burgis | Foley Artist |
| Mark DeSimone | ADR Mixer |
| Zoe Freed | Foley Artist |
| Glenn Freemantle | Sound |
| Glen Gathard | Foley Mixer |
| Chris Navarro | ADR Mixer |
| James Wichall | Dialogue Editor |
| Jemma Riley-Tolch | Foley Editor |
| Emilie O'Connor | Dialogue Editor |
| Kamen Glover | Makeup Artist |
| Heather Manson | Makeup Artist |
| Chris Lyons | Special Effects Makeup Artist |
| Nathaniel De'Lineadeus | Special Effects Makeup Artist |
| Sarah Weatherburn | Wigmaker |
| Christopher Wyatt | Art Direction |
| Patrick Rolfe | Production Design |
| Orlin Grozdanov | Set Decoration |
| Rachael Fleming | Costume Design |
| Allon Reich | Executive Producer |
| Irvine Welsh | Executive Producer |
| John Gorman | Property Master |
| Julian Spencer | Stunt Coordinator |
| David Gilchrist | First Assistant Director |
| Janice Macrae | Set Decoration Buyer |
| Arwel Evans | Standby Art Director |
| Lorna Houlihan | Assistant Art Director |
| Emer O'Sullivan | Scenic Artist |
| Zoe Wight | Scenic Artist |
| Alice Walker | Art Department Assistant |
| Natalie Astridge | Assistant Set Decoration |
| Alastair Rae | "B" Camera Operator |
| Alastair Rae | Steadicam Operator |
| John Watters | First Assistant "A" Camera |
| Derrick Peters | First Assistant "B" Camera |
| Dan Henderson | Second Assistant "A" Camera |
| Chris Maxwell | Second Assistant "B" Camera |
| Thomas Bryan | Camera Trainee |
| Dan Carling | Digital Imaging Technician |
| Sean Walker | Video Assist Operator |
| Garry Fraser | Second Unit Director |
| Zoe Liang | Second Unit First Assistant Director |
| Harry Boyd | Second Unit First Assistant Director |
| Michael Queen | Second Assistant Director |
| Katharine K.K. Kennedy | Crowd Assistant Director |
| Alex McKay | Third Assistant Director |
