 | Paul Giamatti als Screw-On Head (voice) |
 | David Hyde Pierce als Emperor Zombie (voice) |
 | Patton Oswalt als Mr. Groin (voice) |
 | Corey Burton als President Abraham Lincoln / Demon / Professor Faust (voice) |
 | Mindy Sterling als Aggie / Geraldine (voice) |
 | Molly Shannon als Patience the Vampire (voice) |
| Chris Prynoski | Director |
| Mike Mignola | Writer |
| Bryan Fuller | Writer |
| Bryan Fuller | Executive Producer |
| Jason Netter | Executive Producer |
| Ken F. Levin | Producer |
| Susan Corbin | Producer |
| David W. Foster | Editor |
| Pierpaolo Tiano | Original Music Composer |
| Mike Mignola | Art Direction |
