 | Robert De Niro als Don Griffin |
 | Diane Keaton als Ellie Griffin |
 | Ben Barnes als Alejandro 'Alex' Soto Griffin |
 | Amanda Seyfried als Missy O'Connor |
 | Susan Sarandon als Beatrice 'Bebe' McBride |
 | Katherine Heigl als Lyla Griffin |
 | Topher Grace als Jared Griffin |
 | Christine Ebersole als Muffin O'Connor |
 | David Rasche als Barry O'Connor |
 | Patricia Rae als Madonna Soto |
 | Ana Ayora als Nuria Soto |
 | Robin Williams als Father Monaghan |
 | Kyle Bornheimer als Andrew |
 | Christa Campbell als Kim |
 | Megan Ketch als Jane |
 | Ian Blackman als Maitre d' |
 | Shana Dowdeswell als Waitress |
 | Doug Torres als Waiting Father |
 | Marvina Vinique als Mother |
 | Joshua Nelson als Worker |
 | Quincy Dunn-Baker als Kevin |
 | Sylvia Kauders als Elderly Wife |
 | Edmund Lyndeck als Elderly Husband |
 | John V. Barbieri als Wedding Guest |
| Justin Zackham | Director |
| Nathan Barr | Original Music Composer |
| Harry J. Ufland | Producer |
| Jean-Stéphane Bron | Screenstory |
| Karine Sudan | Screenstory |
| Jonathan Corn | Editor |
| Richard Salvatore | Producer |
| Justin Zackham | Producer |
| Barbara Fiorentino | Casting |
| Clay Pecorin | Producer |
| Andrew Jackness | Production Design |
| Justin Zackham | Screenplay |
| Anthony Katagas | Producer |
| Thierry Spicher | Executive Producer |
| Philippe Martin | Executive Producer |
| Michael Paseornek | Executive Producer |
| Jason Constantine | Executive Producer |
| Eda Kowan | Executive Producer |
| Avi Lerner | Executive Producer |
| Danny Dimbort | Executive Producer |
| Trevor Short | Executive Producer |
| Boaz Davidson | Executive Producer |
| John Thompson | Executive Producer |
| Matthew O'Toole | Co-Producer |
| Jonathan Brown | Director of Photography |
| Aude Bronson-Howard | Costume Designer |
| Anthony Katagas | Unit Production Manager |
| Doug Torres | First Assistant Director |
| Francisco Ortiz | Second Assistant Director |
