 | Karen Gillan als Carol Cobb |
 | Iris Apatow als Krystal Kris |
 | Fred Armisen als Darren Eigen |
 | Maria Bakalova als Anika |
 | Vir Das als Ronjon |
 | David Duchovny als Dustin Mulray |
 | Samson Kayo als Bola |
 | Keegan-Michael Key als Sean Knox |
 | Guz Khan als Howie Frangopolous |
 | Leslie Mann als Lauren Van Chance |
 | Kate McKinnon als Paula the Studio Head |
 | Pedro Pascal als Dieter Bravo |
 | Peter Serafinowicz als Gavin |
 | Harry Trevaldwyn als Gunther |
 | Danielle Vitalis als Pippa |
 | Rob Delaney als Carol's Agent, Marti |
 | Raphael Acloque als Zaki |
 | Chris Witaske als Josh |
 | Galen Hopper als Carla |
| Ross Lee als Mr. Best |
| Nick Kocher als Scott The EPK Guy |
 | Celeste Dring als Martha the Script Supervisor |
 | Ben Ashenden als Tip the MoCap Guy |
 | Alexander Owen als Cyril the MoCap Guy |
| Audrina Woolrich als Josh's Daughter |
| Grant Woolrich als Josh's Son |
| Grant Fear als Falcon Handler |
| Maria Bamford als Krystal's Mom |
| Katie O'Brien als Baltaire Waitress, Monica |
 | Daisy Ridley als Kate |
 | John Lithgow als Tom the Studio Chairman |
| Austin Ku als Li the Executive Chairman |
 | John Cena als Steve the Stunt Coordinator |
 | Beck als Beck |
 | Donna Air als ET Reporter, Susan Howard |
 | Ivy Wolk als Anti-Krystal YouTuber |
 | James McAvoy als James McAvoy |
 | Kathryn Drysdale als Zaki's Wife, Minnie |
 | Vivian Full als Second ET Reporter |
| Chloé Delanney als Third ET Reporter |
| Judd Apatow | Director |
| Barry Mendel | Executive Producer |
| Judd Apatow | Producer |
| Donald Sabourin | Executive Producer |
| Pam Brady | Executive Producer |
| Ben Smithard | Director of Photography |
| Dan Schalk | Editor |
| James Thomas | Editor |
| Andrew Bird | Original Music Composer |
| Andrew Dawson | Co-Producer |
| Steve Dawson | Co-Producer |
| Tim Inman | Co-Producer |
| Savannah Kelly | Associate Producer |
| David King | Co-Producer |
| Judah Miller | Co-Producer |
| Deena Rosenblatt | Associate Producer |
| Victor Jenkins | Casting |
| Gayle Keller | Casting |
| Neal Callow | Art Direction |
| Paul Ghirardani | Supervising Art Director |
| Virginia Reina | Standby Art Director |
| Lynsey Moore | Costume Design |
| Samuel James | Wigmaker |
| Joseph Whitmeyer | Hairstylist |
| Rosie Sinfield | Makeup Artist |
| Laura Schalker | Hair Supervisor |
| Laura Schalker | Makeup Supervisor |
| Matiki Anoff | Key Makeup Artist |
| A.J. Blackadder | Hairstylist |
| Chris Fitzpatrick | Prosthetic Supervisor |
| Cassandra Garcia | Makeup Artist |
| Denise Kum | Hair Designer |
| Denise Kum | Makeup Designer |
| Emily Loutit | Makeup Trainee |
| Emily Loutit | Hair Assistant |
| Jodi Mancuso | Key Hair Stylist |
| Scott Eaton | Production Supervisor |
| James O'Donnell | Second Unit Director |
| Michael Kriaris | Unit Production Manager |
| Lisa Rodgers | Post Production Supervisor |
| Nancy Valle | Executive In Charge Of Post Production |
| William Booker | Second Unit First Assistant Director |
| Robbie Davidson | Third Assistant Director |
| James Excell | Third Assistant Director |
| Hannah Gray | Set Production Assistant |
| Camille Hatcher | Set Production Assistant |
| Annie Hitchcock | Crowd Assistant Director |
| Ben Howard | First Assistant Director |
| Charlotte Amelia Miles | Third Assistant Director |
| Jason Rickwood | Second Second Assistant Director |
| Mark Layton | Second Second Assistant Director |
| Charlie Vaughan | Second Assistant Director |
| Anna Behlmer | Sound Re-Recording Mixer |
| Miriam Cole | ADR Editor |
| Frédéric Dubois | Sound Editor |
| Steve Finn | Production Sound Mixer |
| Kevin Froines | Sound Mix Technician |
| Tavish Grade | Foley Mixer |
| Thomas Kennedy | Second Assistant Sound |
| Paul Lynch | ADR Recordist |
| Michael Maroussas | Dialogue Editor |
| Richard Morgan | Cableman |
| Eric Offin | Foley Editor |
| Mikel Parraga-Wills | Foley Mixer |
| Daniel Saxlid | Dialogue Editor |
| Drew Webster | Sound Mix Technician |
| Mark Holt | Special Effects Supervisor |
| Ben James | Special Effects Technician |
| Nick Kool | Special Effects Technician |
| Peter Treece | Special Effects Technician |
| Aimee Watret | Special Effects Coordinator |
| Phil Arntz | Aerial Director of Photography |
| Michael Andrews | Original Music Composer |
| Judd Apatow | Writer |
| Pam Brady | Writer |
| Mark Tildesley | Production Design |
| Matt Biffa | Music Supervisor |
| Roger Guyett | Visual Effects Designer |
| Russell Earl | Visual Effects Supervisor |
| Ryan Heffington | Choreographer |
| Michelle Mullen | Unit Production Manager |
| Peter Miles | Stunt Coordinator |
| James Embree | Fight Choreographer |
| Nev Medhurst | Utility Stunts |
| Sina Ali | Stunts |
| Tom Boney | Stunts |
| James Harris | Stunts |
| Alan Leong | Stunts |
| Conor Parish | Stunts |
| Neil Stoddart | Stunts |
| Corey Walkes | Stunts |
| David Reynolds | Additional Music |
| Helen Steinway Bailey | Stunts |
| David Cheung | Stunts |
| Paul Ginns | Stunts |
| Donovan Louie | Stunts |
| Rashid Phoenix | Stunts |
| Arran Topham | Stunts |
| Vincent Wang | Stunts |
| Lloyd Bass | Stunts |
| Leon Chee | Stunts |
| Mélissa Humler | Stunts |
| John Macdonald | Stunts |
| Ali Ryan | Stunts |
| Chris Waite | Stunts |
| Marcus White | Stunts |
| Debra Neil-Fisher | Additional Editor |
| David Dean | Additional Editor |
| Craig Herring | Additional Editor |
| Thomas Billings | Stunts |
| David Garrick | Stunts |
| Maureen Lavoyer | Stunts |
| Avril Murphy | Stunts |
| Fenix Searle | Stunts |
| Elmo Walker | Stunts |
| Leo Woodruff | Stunts |
| Celestria Kimmins | Art Direction |
| Georgina Devine | Assistant Art Director |
| Alice Felton | Set Decoration |
| Erin Coutts | Assistant Set Decoration |
| Anna Cumming | Assistant Set Dresser |
| Betty Sims-Hilditch | Assistant Set Dresser |
| Sashi Kissoon | "C" Camera Operator |
| Andrei Austin | "B" Camera Operator |
| Andrei Austin | Steadicam Operator |
| Tristan Haley | First Assistant "A" Camera |
| Gabriel Hyman | First Assistant "B" Camera |
| Amber Osborne | Second Assistant "A" Camera |
| Moe Owoborode | Second Assistant "B" Camera |
| Sam Smith | First Assistant "C" Camera |
| Alan Robert Hopkins | Digital Imaging Technician |
| Ben Johnson | Property Master |
| Adrian Platt | Assistant Property Master |
| Tim Hamblyn | Standby Property Master |
| Milos Momcilovic | Boom Operator |
| Tateum Kohut | Sound Re-Recording Mixer |
| Bobby Mackston | Supervising Sound Editor |
| Bobby Mackston | Sound Designer |
| Delaney Del Vecchio | First Assistant Editor |
| Chelsea Dinsdale | First Assistant Editor |
| Daniela Ovi | First Assistant Editor |
| Nathan Bruner | Assistant Editor |
| Meryl Goodwin | Other |
| Holly Freeman | Costume Supervisor |
| Rosie Lack | Assistant Costume Designer |
| Marco De Luca | Costume Coordinator |
| Liz Essex | Wardrobe Master |
| Carla Murtagh | Costume Assistant |
| Amy Brady | Other |
| Laura Miles | Script Supervisor |
| Mark Clayton | Gaffer |
| Nicholas Clarke | Electrician |
| Dak Kannan | Electrician |
| Mike Parsons | Electrician |
| Joshua Lewis-Green | Electrician |
| Milo Smyth | Genetator Operator |
| Jack Farrow | Electrician |
| Tahira Herold | Makeup & Hair |
| Sara Osborn | Makeup & Hair |
| Joyce Iwuozo | Makeup & Hair |
| Sally Rose Davidson | Makeup & Hair |
| Mary Cooke | Makeup & Hair |
| Abi Hobson | Makeup & Hair |
| Maureen Hetherington | Makeup & Hair |
| Kelsey-Leigh Walker | Makeup & Hair |
| Federica Adorno | Makeup & Hair |
| Rachel Sweeney | Makeup & Hair |
| Naomi Tolan | Makeup & Hair |
| Amanda Willgrave | Set Decoration |
| Michelle Brattson | Executive In Charge Of Production |
| Steve Bohan | Construction Manager |
| Matt Chisholm | Props |
| Temple Clark | Storyboard Artist |
| Jessie Curran | Property Master |
| Lottie Geliot | Concept Artist |
| Rohan Harris | Scenic Artist |
| Casey Ivall | Set Decorating Coordinator |
| Tommy Janulis | Assistant Property Master |
| Gabrielle Leon | Graphic Designer |
| Adrian Makarewicz | Art Department Assistant |
| Adrian Makarewicz | Standby Art Director |
| Sophie Powell | Graphic Designer |
| Corrine Silver | Draughtsman |
| Swapnil Ambre | Visual Effects Producer |
| Sarvesh Amre | Visual Effects Production Manager |
| Jill Brooks | Visual Effects Producer |
| Gayle Busby | Visual Effects Producer |
| Galo Gutiérrez | Visual Effects Supervisor |
| Jack Hawkes | Visual Effects Production Manager |
| Karen Kelly | Visual Effects Producer |
| Shawn Kelly | Animation Supervisor |
| George Loucas | Visual Effects Supervisor |
| Brooke Meacham | Visual Effects Production Manager |
| Isha Nigam | Visual Effects Supervisor |
| Dan Pearson | Data Wrangler |
| Nolan Reese | Visual Effects Editor |
| Nolan Reese | VFX Editor |
| Matt Russell | Visual Effects Producer |
| Jackie Stone | Visual Effects Production Manager |
| Sam Willing | VFX Editor |
| Daniela Cazmal | Costume Standby |
| Bethany Scarrott | Costumer |
| Georgia Walsh | Costume Supervisor |
| Ryan Castle | Supervising Music Editor |
| Greg Hayes | Scoring Mixer |
| Steve Kempster | Scoring Mixer |
| Stephen Perone | Music Editor |
| Oren Yaacoby | Music Editor |
| Lois Gration | Script Coordinator |
| James O'Donnell | Stunt Coordinator |
