 | Johnny Depp als Jack Sparrow |
 | Orlando Bloom als Will Turner |
 | Keira Knightley als Elizabeth Swann |
 | Stellan Skarsgård als William "Bootstrap Bill" Turner |
 | Bill Nighy als Davy Jones |
 | Jack Davenport als James Norrington |
 | Kevin McNally als Joshamee Gibbs |
 | Jonathan Pryce als Weatherby Swann |
 | Lee Arenberg als Pintel |
 | Mackenzie Crook als Ragetti |
 | Tom Hollander als Cutler Beckett |
 | Naomie Harris als Tia Dalma |
 | David Bailie als Cotton |
 | Martin Klebba als Marty |
 | David Schofield als Ian Mercer |
 | Alex Norton als Bellamy |
 | Dermot Keaney als Maccus |
 | Andy Beckwith als Clanker |
 | Clive Ashborn als Koleniko |
 | Reggie Lee als Headless |
 | Christopher Adamson als Jimmy Legs |
 | Jonathan Linsley als Ogilvey (uncredited) |
| John Boswall als Burser (uncredited) |
 | Max Baker als Burser - Edinburgh (uncredited) |
 | Steve Speirs als Quartermaster - Edinburgh (uncredited) |
 | Lauren Maher als Scarlet (uncredited) |
 | Vanessa Branch als Giselle (uncredited) |
 | Luke de Woolfson als Frightened Sailor (uncredited) |
 | Jonathan Kite als Black Pearl Pirate (uncredited) |
 | Ho-Kwan Tse als Ho-Kwan (uncredited) |
 | Peter Donald Badalamenti II als Penrod (uncredited) |
| Christopher S. Capp als Cotton's Parrot (voice) (uncredited) |
 | Donald Dowd als Swamp Dweller (uncredited) |
 | Barry McEvoy als Carruthers' Guard (uncredited) |
| Claudia Adams als (uncredited) |
| Filip Cvijetic als A tree seen in the movie |
 | Michael Enright als Deckhand - Edinburgh |
 | Geoffrey Rush als Hector Barbossa |
| Craig Wood | Editor |
| Hans Zimmer | Original Music Composer |
| Rick Heinrichs | Production Design |
| Ve Neill | Makeup Department Head |
| Dariusz Wolski | Director of Photography |
| Eric McLeod | Executive Producer |
| Stephen E. Rivkin | Editor |
| Bruce Hendricks | Executive Producer |
| Gore Verbinski | Director |
| Jerry Bruckheimer | Producer |
| Chad Oman | Executive Producer |
| Mike Stenson | Executive Producer |
| Ted Elliott | Screenplay |
| Terry Rossio | Screenplay |
| Denise Chamian | Casting |
| Cedric Nicolas-Troyan | Visual Effects |
| James Ward Byrkit | Conceptual Design |
| Camille Friend | Hairstylist |
| Charles Gibson | Visual Effects |
| Sala Baker | Stunts |
| Mickael Coedel | Animation |
| Stacy Horn | Key Costumer |
| George Watters II | Supervising Sound Editor |
| John Knoll | Visual Effects Supervisor |
| Hal Hickel | Animation Supervisor |
| Christopher Boyes | Sound Mixer |
| Cheryl Carasik | Set Decoration |
| Allen Hall | Special Effects Supervisor |
| Christopher Boyes | Supervising Sound Editor |
| Paul Massey | Sound Mixer |
| Lee Orloff | Sound Mixer |
| Penny Rose | Costume Design |
| John Dexter | Supervising Art Director |
| William Hawkins | Art Direction |
| Eric McLeod | Unit Production Manager |
| Jeffrey Schwartz | Second Second Assistant Director |
| Jeff Okabayashi | Second Assistant Director |
| David A. Arnold | Dialogue Editor |
| Tami Goldman | Production Supervisor |
| Charles Gibson | Second Unit Director |
| William Ladd Skinner | Art Direction |
| Douglas C. Merrifield | Unit Production Manager |
| Thomas Hayslip | Production Supervisor |
| Steven F. Beaupre | Second Second Assistant Director |
| Ulrika Akander | Dialogue Editor |
| Peter Kohn | First Assistant Director |
| James Ashwill | Foley Mixer |
| Bruce Crone | Art Direction |
| David H. Venghaus Jr. | First Assistant Director |
| Gary Romolo Fiorelli | Second Unit First Assistant Director |
| Steve Buscaino | Prosthetic Supervisor |
| Barbara Ohren | Seamstress |
| Natasha Allegro | Hairstylist |
| Bob Kretschmer | Wigmaker |
| Brigham Taylor | Production Executive |
| Joel Harlow | Key Makeup Artist |
| Pat Sandston | Associate Producer |
| David Alban | Carpenter |
| Bob Skemp | Greensman |
| Mark 'Crash' McCreery | Conceptual Design |
| Alexander Marc Calle | Assistant Art Director |
| Lucia Mace | Key Hair Stylist |
| Francesco Franco Ferrara | Painter |
| Roger Meilink | Rigging Gaffer |
| Peter Zuccarini | Underwater Director of Photography |
| Joshua Spencer | Editorial Coordinator |
| James Diggs | Standby Painter |
| Tami Goldman | Post Production Supervisor |
| Vicki Galloway Weimer | Visual Effects Production Manager |
| Mario Capellari | Sequence Supervisor |
| Mike Anderson | Boom Operator |
| Chris Bennett | Lighting Technician |
| David Luckenbach | Steadicam Operator |
| Jason Rainey | Ager/Dyer |
| Greg John Callas | Construction Coordinator |
| Kurt Smith | Color Timer |
| Kevin Connolly | Musician |
| Melissa Lytle | Assistant Sound Editor |
| Jesse Jam Miranda | Casting |
| Chuck Rousseau | Armorer |
| Sharron Reynolds-Enriquez | Script Supervisor |
| Duncan Blackman | Layout Supervisor |
| Olivier Arnesen | Production Coordinator |
| Brooke Brunson | Set Dresser |
| Dee Selby | Assistant Sound Designer |
| Alex Cruz | Grip |
| Sean Clouser | Construction Foreman |
| Ron Kunecke | Transportation Captain |
| Scott E. Metzger | 3D Artist |
| Sean Andrew Faden | CG Supervisor |
| Diana Miao | Lighting Supervisor |
| George Marshall Ruge | Stunt Coordinator |
| David B. Nowell | Aerial Director of Photography |
| Joe Duarte | Rigging Grip |
| Scott Stoddard | Sculptor |
| John Malvino | Underwater Camera |
| Kris Peck | Property Master |
| Scout Masterson | Casting Associate |
| Tranel Bland | Post Production Assistant |
| Bobby Enriquez | Driver |
| Kathleen Rosen | Set Decoration Buyer |
| Robert Fechtman | Set Designer |
| Sophia Spink | Assistant Costume Designer |
| Matthew Harrison | Foley Editor |
| Carla S. Nemec | Art Department Coordinator |
| Darek Gogol | Production Illustrator |
| Lea Anderson | Craft Service |
| Ryan Kautzman | Software Engineer |
| James Ward Byrkit | Storyboard Artist |
| Rafael E. Sánchez | Gaffer |
| Bob Badami | Music Supervisor |
| Lucy Bowring | Costume Coordinator |
| Rick Chavez | Assistant Property Master |
| Juan Peralta | Mix Technician |
| Darrell Warner | Costume Illustrator |
| Steve Gell | Textile Artist |
| Jeane Wong | Production Intern |
| Laura Gary | Studio Teacher |
| Lee Auerbach | Electrician |
| Laurence B. Davis | Propmaker |
| Brad Edmiston | First Assistant Camera |
| Carla Meyer | Dialect Coach |
| Tyson Fountaine | Contact Lens Technician |
| Julie Jones | Production Controller |
| Huseyin Caner | Visual Effects Supervisor |
| David D. Scott | Video Assist Operator |
| Doreen Austria | Graphic Designer |
| Peter Mountain | Still Photographer |
| John Bugarcic | Set Painter |
| Robert Allen | Set Medic |
| Kevin Pitcairn | Stand In |
| Kelly Farrah | Props |
| Tanya Nienhouse | Post Production Accountant |
| Jarek Gorczycki | Best Boy Electric |
| Simon Morgan | First Assistant Editor |
| Julie Creighton | Visual Effects Coordinator |
| Christopher S. Capp | Visual Effects Editor |
| Selena Evans-Miller | Assistant Makeup Artist |
| Ned Gorman | Visual Effects Producer |
| Scott R. Hankins | Principal Costumer |
| Clark Credle | Additional Second Assistant Director |
| Christopher Boyes | Sound Designer |
| David Ebner | Digital Effects Supervisor |
| Robert Alonzo | Stunts |
| Mitch Toles | Special Effects |
| Jeff Dash | Production Accountant |
| Tyson Fountaine | Contact Lens Painter |
| Beau Desmond | Costumer |
| Marina Marit | Key Set Costumer |
| Charles Gibson | Second Unit |
| Martin Schaer | Camera Operator |
| Guy Friedman | Security |
| Michael Singer | Unit Publicist |
| J. Michael Popovich | Key Grip |
| Rick Giovinazzo | Orchestrator |
| Brinton Bryan | Set Production Assistant |
| Brent Burge | Sound Effects Editor |
| Mauro Borrelli | Concept Artist |
| Ryan Rakel | Camera Department Production Assistant |
| Dan Goslee | Digital Intermediate Assistant |
| Julie Feiner | ADR Editor |
| Colin Cooper | ADR Mixer |
| Rico Bailey | Location Assistant |
| Chrysta Marie Burton | Visual Effects Production Assistant |
| Barbara Harris | ADR Voice Casting |
| Yvette Gonzalez | Post Production Coordinator |
| Hector Gutierrez | Dolly Grip |
| Stefan Sonnenfeld | Digital Color Timer |
| Kindra Marra | Assistant Editor |
| Jeanette Browning | ADR Recordist |
| Jessica Gallavan | Supervising ADR Editor |
| Angela Demo | Casting Assistant |
| Derek Casari | ADR Engineer |
| Teri E. Dorman | Supervising Dialogue Editor |
| Julie Pearce | Music Editor |
| Matthew C. Blea | Second Assistant Camera |
| Javier Arrieta | Set Costumer |
| Steve Hart | Location Manager |
| Nino Neuboeck | First Assistant "B" Camera |
| Steve Nichols | Lead Animator |
| Julia Neighly | Visual Effects Production Manager |
| Linda Kai | Assistant Location Manager |
| Tony Angelotti | Stunt Double |
| Dave Robling | Transportation Coordinator |
| Lenny Rabinowitz | ADR Recording Engineer |
| Julie Hooker Baker | Special Effects Assistant |
| Chris Hampton | Special Effects Technician |
| Nathan McGuinness | Senior Visual Effects Supervisor |
| Ken Crouch | Costume Supervisor |
| Christopher Barnett | Sound Mix Technician |
| Jimmy Lillard | Visual Effects Assistant Editor |
| John D. Miller | Best Boy Grip |
| Lance Mayer | Libra Head Technician |
| Des Carey | Digital Intermediate Producer |
| Dan O'Connell | Foley Artist |
| Rick O'Connor | CG Animator |
| Laura Boyer | Assistant Production Coordinator |
| David Paris | Aerial Coordinator |
| Pete Anthony | Conductor |
| Timothy Brakensiek | Creature Technical Director |
| Merlin Carroll | Rotoscoping Artist |
| Rick Roesch | Payroll Accountant |
| Dax A. Cuesta | Second Assistant Accountant |
| Boone Narr | Animal Coordinator |
| Eddie Pasquarello | Compositing Supervisor |
| Jennifer Alessi | Extras Casting |
| Shannan Burkley | Matte Painter |
| Melissa Muik | Supervising Music Editor |
| Vickie M. Hsieh | Travel Coordinator |
| Oscar J. Flores | Production Secretary |
| Ryan Faust | Assistant Accountant |
| Mike Sanders | Digital Supervisor |
| Derek Bird | Digital Compositor |
| Christi Dembrowski | Executive Assistant |
| Andrea Isaacs | Production Executive |
| Barbara Berkery | Dialogue Coach |
| Ryan Adelman | Production Assistant |
| Elissa Bello | Roto Supervisor |
| Phaedra Charlton | First Assistant Accountant |
| Robin De Lano | Extras Casting Assistant |
| Veronica Lorenz | Makeup Artist |
| Armen Ksajikian | Musician |
| Gary Ambrosia | Art Department Assistant |
| Thomas Rosales Jr. | Stunts |
| Caryn Mower | Stunts |
| Lisa Marie Rosenberg | Hairstylist |
| Jay Wolpert | Characters |
| Stuart Beattie | Characters |
| Ted Elliott | Characters |
| Terry Rossio | Characters |
| Deborah Rutherford | Makeup Artist |
| Mark De Alessandro | Stunts |
| Denney Pierce | Stunts |
| Kurt D. Lott | Stunts |
| Kirk Maxwell | Stunt Double |
| Sonia Izzolena | Stunts |
| Henry Kingi Jr. | Stunts |
| Theo Kypri | Stunts |
| J.P. Romano | Stunts |
| John Robotham | Stunts |
| Tom Morga | Stunts |
| Casey O'Neill | Stunts |
| Hugh Aodh O'Brien | Stunts |
| Lincoln Simonds | Stunts |
| Philip Tan | Stunts |
| Jon Valera | Stunts |
| Mark Aaron Wagner | Stunt Double |
| Richard L. Blackwell | Utility Stunts |
| Tsuyoshi Abe | Stunts |
| Jim Palmer | Stunts |
| Mark Norby | Stunts |
| Stephen A. Pope | Stunts |
| Rob Mars | Stunts |
| Don Lee | Stunts |
| Samuel Le | Stunts |
| Derek Mears | Stunts |
| Kori Murray | Stunts |
| Víctor Quintero | Stunts |
| Christopher Leps | Stunts |
| Zach Hudson | Stunt Double |
| Lisa Hoyle | Stunt Double |
| Anthony Kramme | Stunts |
| Stacey Howell-Brown | Stunts |
| Yoshio Iizuka | Stunts |
| Gene Hartline | Stunts |
| Sam Hargrave | Stunts |
| Mickey Giacomazzi | Stunts |
| Dean Grimes | Stunts |
| Jeremy Fry | Stunts |
| Dane Farwell | Stunts |
| Clay Donahue Fontenot | Stunts |
| Sebastian Foxx | Stunts |
| Kofi Elam | Stunts |
| Kiante Elam | Stunts |
| Roel Failma | Stunts |
| Paul Eliopoulos | Stunts |
| Andy Dylan | Stunts |
| Greg Wayne Elam | Stunts |
| Brian Duffy | Stunts |
| Jayson Dumenigo | Stunts |
| J. Mark Donaldson | Stunts |
| Thomas DuPont | Stunt Double |
| Phil Culotta | Stunts |
| Alex Chansky | Stunts |
| Augie Davis | Stunts |
| Jay Caputo | Stunts |
| Keith Campbell | Stunts |
| Brycen Counts | Stunts |
| Brian Bennett | Stunts |
| Richard L. Blackwell | Stunts |
| Noby Arden | Stunts |
| Joey Anaya | Stunts |
| Russell Towery | Stunt Double |
| Addison Teague | Sound Effects Editor |
