 | Idris Elba als Roland Deschain |
 | Matthew McConaughey als Walter O’Dim |
 | Tom Taylor als Jake Chambers |
 | Claudia Kim als Arra Champignon |
 | Fran Kranz als Pimli Prentiss |
 | Abbey Lee als Tirana |
 | Jackie Earle Haley als Richard Sayre |
 | Katheryn Winnick als Laurie Chambers |
 | Dennis Haysbert als Steven Deschain |
 | Michael Barbieri als Timmy |
 | José Zúñiga als Dr. Hotchkiss |
 | Alex McGregor als Susan Delgado |
 | Nicholas Hamilton als Lucas Hanson |
 | De-Wet Nagel als Taheen Tech |
 | Nicholas Pauling als Lon |
 | Eva Kaminsky als Jill |
| Robbie McLean als Toby |
| Matthew Thomson als Jonah |
 | Karl Thaning als Elmer Chambers |
 | Lemogang Tsipa als Phedon |
 | Robert Whitehead als Cantab |
| Leeanda Reddy als Dr. Weizak |
 | Kenneth Fok als Johnny |
| Charlize Churcher als Pretty Girl |
| Victoria Nowak als Injured Child |
| Ben Gavin als Soldier |
| Sara Cicilian als Drunk Girl |
| Lara Adine Lipschitz als Nurse |
| Ella Gabriel als Rose |
 | Jabari Gray als Bystander |
| Paul Riley Fox als Militia |
| Adison Eisenberg als Daughter |
 | Mark Elderkin als Rat Man |
 | Joe Vaz als Worker Taheen |
| Christopher Stein als Big Guard |
| Andre Robinson als Boy in the Park |
 | Alfredo Narciso |
| Dan Hirst als Village Engineer |
| Naomi Poremba als Park Kid |
| Savana Tardieu als Breaker Kid |
| Zak Rowlands als Taheen Tech |
| Christiaan Schoombie als Young Reactor Man |
| Dominique Danielle als Scared Woman |
| David Casper Smith als Imperial Vampire |
| Keci Eatock als Vampire Girl |
| Jake Greenlee als Tom Chambers |
| Jay-Jay Botha als Cult follower |
 | Marmee Cosico als Chinatown Pedestrian |
 | Bill Walters als Homeless Man in Alley |
| Samantha Willoughby als Vampire |
| Alan Edward Bell | Editor |
| Nikolaj Arcel | Director |
| Nikolaj Arcel | Screenplay |
| Akiva Goldsman | Screenplay |
| Anders Thomas Jensen | Screenplay |
| Jeff Pinkner | Screenplay |
| Stephen King | Novel |
| Ron Howard | Producer |
| G. Mac Brown | Executive Producer |
| Cheryl Eatock | Line Producer |
| Akiva Goldsman | Producer |
| Brian Grazer | Producer |
| Trish Hofmann | Executive Producer |
| Stephen King | Producer |
| Erica Huggins | Executive Producer |
| Anders Thomas Jensen | Executive Producer |
| Jeff Pinkner | Executive Producer |
| David H. Venghaus Jr. | Associate Producer |
| Junkie XL | Original Music Composer |
| Rasmus Videbæk | Director of Photography |
| Dan Zimmerman | Editor |
| Marisol Roncali | Casting |
| Mary Vernieu | Casting |
| Christopher Glass | Production Design |
| Oliver Scholl | Production Design |
| Audra Avery | Art Direction |
| Yuri Bartoli | Art Direction |
| Patrick O'Connor | Art Direction |
| Catherine Palmer | Art Direction |
| Anneke Botha | Set Decoration |
| Rosemary Brandenburg | Set Decoration |
| Trish Summerville | Costume Design |
| Madelein Krugell | Key Hair Stylist |
| Megan Tanner | Makeup Artist |
| C. Scott Baker | Set Designer |
| Nico Louw | Sound Mixer |
| Michael J. Broomberg | Foley |
| Guy Hodgen | Camera Operator |
| Sachin Mathew | Animation |
| Ryan Chavez | First Assistant Editor |
| Lara Khachooni | Assistant Editor |
| Joe Krenzer | Assistant Editor |
| Guy Potgieter | Supervising Art Director |
| Brad Ricker | Supervising Art Director |
| Felicity Bowring | Hairstylist |
| Felicity Bowring | Makeup Artist |
| Ruth G. Carsch | Key Hair Stylist |
| Duncan Foster | Conceptual Design |
| Jules Holdren | Hairstylist |
| Jennifer Jefferson | Hairstylist |
| Ann Pala | Makeup Department Head |
| Nadine Prigge | Makeup Department Head |
| Nadine Prigge | Hair Department Head |
| Nancy Tong | Hair Department Head |
| Marika Weber | Key Makeup Artist |
| Marika Weber | Key Hair Stylist |
| Adam Brightman | Unit Production Manager |
| Marc A. Hammer | Unit Production Manager |
| Carol Heij | Production Manager |
| Trish Hofmann | Unit Production Manager |
| Kelly Todd | Production Supervisor |
| Hercules Malan | Assistant Director |
| Isabel Martens | Second Assistant Director |
| David H. Venghaus Jr. | First Assistant Director |
| Kimberly Asa | Art Department Coordinator |
| Laurent Ben-Mimoun | Conceptual Illustrator |
| Liz Chancey | Art Department Assistant |
| Trevor Goring | Storyboard Designer |
| Collin Grant | Storyboard Designer |
| Anthony Liberatore | Storyboard Designer |
| Kyle Marchiafava | Set Dresser |
| Etienne Maree | Set Dresser |
| Abner Marín | Creature Design |
| Jeffrey D. McDonald | Assistant Art Director |
| David Meyer | Set Designer |
| David M. Milstien | Leadman |
| Thomas A. Nelson | Storyboard Designer |
| Josh Roth | Property Master |
| Juan Sanchez | Assistant Art Director |
| Malwande Sigabi | Set Designer |
| Pravika Singh | Set Designer |
| Christo Strydom | Art Department Coordinator |
| Dan Sweetman | Storyboard Designer |
| Sam Tung | Storyboard Designer |
| Kerry van Lillenveld | Property Master |
| Lisa Van Velden | Set Designer |
| Tom Caton | Boom Operator |
| Libero Colimberti | Boom Operator |
| Kira Smith | Boom Operator |
| Sarah Bourgeois | Assistant Sound Editor |
| Chris Diebold | Sound Effects Editor |
| Lee Gilmore | Sound Effects Editor |
| Ralph Osborn | Dialogue Editor |
| Jeremy Peirson | Supervising Sound Editor |
| Mark Weingarten | Sound Mixer |
| Peter Schneider | Sound Mixer |
| Burt Dalton | Special Effects Coordinator |
| Nathan Barris | Fight Choreographer |
| Myra 'Dakota' Bown | Stunts |
| Nikki Brower | Stunts |
| Eric Brown | Stunts |
| Peter Bucossi | Stunt Coordinator |
| Mike Burke | Stunts |
| Kabelo Bouga Chalatsane | Stunts |
| Jacques du Plessis | Stunts |
| Dewaldt Du Preez | Stunts |
| Jake Eavey | Stunts |
| Toni Jean Erasmus | Stunts |
| Matt Esof | Stunts |
| Brenda Firmani | Stunts |
| Jim Ford | Stunts |
| Warren Germishuys | Stunts |
| Damian Green | Stunts |
| Kerry Gregg | Stunt Coordinator |
| Garrett Hammond | Stunts |
| Paul Hampshire | Stunts |
| Greg Harvey | Stunts |
| Jenna Hellmuth | Stunts |
| Dan Hirst | Stunts |
| Jermaine Holt | Stunts |
| Grant Hulley | Stunt Coordinator |
| Allen Irwin | Stunts |
| Ben Jenkin | Stunts |
| Malin Kirjonen | Stunts |
| Hiro Koda | Stunts |
| Shane John Kruger | Stunts |
| Tim Lajcik | Stunts |
| Roberto Lopez | Stunts |
| Emmanuel Manzanares | Fight Choreographer |
| Alwyn Marx | Stunts |
| James Northrup | Stunts |
| Larry Nuñez | Stunts |
| Travis Parker | Stunts |
| J.J. Perry | Stunt Coordinator |
| Christopher Place | Stunts |
| Thomas Place | Stunts |
| Vlad Rimburg | Stunts |
| Troy Robinson | Stunts |
| Noah Schultz | Stunts |
| Rose Sias | Stunts |
| Robbie P Smith | Stunts |
| Frans Steyn | Stunts |
| Nuo Sun | Stunts |
| Taheen Tracker | Stunts |
| Ross Van Der Walt | Stunts |
| Matthew Van Leeve | Stunts |
| Shawn Van Zyl | Stunts |
| Ian Williamson | Stunts |
| Mitchell Amundsen | Director of Photography |
| Paul Avery | Best Boy Electric |
| Eric Boncher | Gaffer |
| David Emmerichs | Steadicam Operator |
| David Emmerichs | Camera Operator |
| Pete Escobar | Grip |
| Frank Gardner | First Assistant Camera |
| Jed Harris | Electrician |
| Justin Holdsworth | Gaffer |
| Rob Koch | First Assistant Camera |
| Selemani Mahango | Electrician |
| Nasmie Majiet | Key Grip |
| Riyaad Majiet | Dolly Grip |
| Moses Makateng | Electrician |
| Matthew Pebler | Camera Operator |
| Sarel Pretorius | Camera Operator |
| Rob Riccobono | Best Boy Electric |
| Jim Shelton | Key Grip |
| Adam Sudtell | Key Grip |
| Sven Vosloo | Camera Operator |
| Oliver Wilter | Gaffer |
| Alex Worster | First Assistant Camera |
| Mike Yurich | Key Grip |
| Shane Richards | Animation |
| Valentina Aulisi | Key Costumer |
| Joseph Cigliano | Costume Supervisor |
| Sarah Dano | Set Costumer |
| Mia Hofmann | Costume Supervisor |
| Jimmy McBride | Tailor |
| Tim McKelvey | Wardrobe Supervisor |
| Kelly Porter | Costume Supervisor |
| Rudy Rojas | Set Costumer |
| Rachel Watson | Assistant Editor |
| Matthew Bernstein | Location Manager |
| Steven Carbajal | Location Manager |
| Patty Carey | Location Scout |
| Peter Costelli | Location Manager |
| Deon Du Preez | Location Manager |
| John Rakich | Location Scout |
| Jonathan Beard | Orchestrator |
| Jordan Cox | Music |
| Morag Cameron | Script Supervisor |
| Bernard L. Eatmon | Script Supervisor |
| Susan Hegarty | Dialect Coach |
| Susan Malerstein | Script Supervisor |
| Carla Meyer | Dialect Coach |
| Carien Schutte | Script Supervisor |
| Sarah Sprague | Production Coordinator |
| Dezi Rorich | Unit Publicist |
| Neil Swain | Dialect Coach |
| James Luccarda | Location Scout |
