 | Nell Tiger Free als Margaret |
 | Ralph Ineson als Father Brennan |
 | Sônia Braga als Sister Silva |
 | Bill Nighy als Cardinal Lawrence |
 | María Caballero als Luz |
 | Nicole Sorace als Carlita |
 | Tawfeek Barhom als Father Gabriel |
 | Charles Dance als Father Harris |
 | Ishtar Currie Wilson als Sister Anjelica |
 | Andrea Arcangeli als Paolo |
 | Guido Quaglione als Alfonzo |
 | Dora Romano als Sister Romano |
 | Michelangelo Dalisi als Luca |
 | Anton Alexander als Father Spiletto |
 | Mia McGovern Zaini als Beatrice |
 | Eugenia Delbue als Pregnant Woman |
| Charita Cecamore als Red Headed Girl |
| Federica Santoro als Smoking Nun |
 | Donatella Bartoli als Nun #1 |
| Marial Bajma-Riva als Nun #2 |
 | Mario Opinato als Doctor |
 | Rachel Hurd-Wood als Katherine Thorn |
| Nicola Garofalo als Obstetrician |
| Marcello Paesano als Waiter |
| Giacomo Henri Dossi als Museum Security Guard |
 | Sylvia Panacione als Nurse #1 |
| Daniela Barra als Nurse #2 |
| Alessandra Fallucchi als Nurse #3 |
 | Milena Božić als Young Sister Silva |
 | Dobrila Stojnic als Comforting Nun |
 | Alberto Tierrez als Shadowy Priest |
| Ljiljana Žunić als Sadistic Nun |
 | Eva Ras als Angry Nun |
 | Miodrag Rakočević als Shadowy Figure |
 | James Swanton als Jackal Performer |
| Andjelko Pavlović als Jackal Performer |
| Mina Knežević als Infant / Newborn (1 Month Old) |
| Ema Nastić als Infant / Newborn (1 Month Old) |
| Mateja Nesovic als Baby Layla |
| Lana Stanojević als Baby Layla |
| Borislav Bogosavac als Scaffold Worker |
| Dejan Dragosavac als Scaffold Worker |
| Darko Corovic als Scaffold Worker |
| Strahinja Despic als Scaffold Worker |
 | Amy Clayton als Margaret Picture Double |
| Amalia Strand als Carlita Picture Double |
| Nigel Dyson als Cardinal Lawrence Picture Double |
| David S. Goyer | Producer |
| Arkasha Stevenson | Director |
| Arkasha Stevenson | Screenplay |
| David Seltzer | Characters |
| Tim Smith | Screenplay |
| Tim Smith | Executive Producer |
| Keith Levine | Producer |
| Aaron Morton | Director of Photography |
| Amy E. Duddleston | Editor |
| Keith Thomas | Screenplay |
| Ben Jacoby | Story |
| Whitney Brown | Executive Producer |
| Gracie Wheelan | Executive Producer |
| Bob Murawski | Editor |
| Kharmel Cochrane | Casting |
| Peter Arpesella | ADR & Dubbing |
| Eve Stewart | Production Design |
| Paco Delgado | Costume Design |
| Mark Korven | Music |
| Elisabetta De Leonardis | Hair Department Head |
| Jasmina Banović | Key Hair Stylist |
| Michela Barberini | Key Hair Stylist |
| Laura Fiasco | Additional Hairstylist |
| Jovana Jovanović | Hairstylist |
| Nataša Krstić | Makeup Designer |
| Federico Laurenti | Makeup Designer |
| Petra Macura | Makeup Artist |
| Ludovica Marini | Assistant Makeup Artist |
| Karina Muzzio | Makeup Artist |
| Tiberio Nardi | Key Makeup Artist |
| Valentina Parrino | Assistant Makeup Artist |
| Stefania Trippa | Makeup Artist |
| Rebecca Sorbi | Assistant Makeup Artist |
| Grazia Maria Giorgi | Assistant Hairstylist |
| Raffaella Iorio | Makeup Supervisor |
| Ana Biskupljanin | Production Manager |
| Sabina Angeloni | Assistant Art Director |
| Giulia Berardi | Assistant Art Director |
| Manuela Assennato | Art Department Coordinator |
| Dubravko Bjelajac | Set Dresser |
| Dionisia Cirasola | Assistant Set Decoration |
| Sergio Cosulich | Assistant Art Director |
| Jonathan Davis | Storyboard Artist |
| Carlo Diamantini | Prop Maker |
| Arianna Ferrazin | Assistant Property Master |
| Francesco Grant | Storyboard Artist |
| Andrea Migliaccio | Standby Art Director |
| Marko Milošević | Standby Property Master |
| Craig Price | Property Master |
| AnaMarija Spasenovic | Property Master |
| Keith Thompson | Creature Design |
| Nađa Trajković | Assistant Set Decoration |
| Genadi Vanchev Tsenov | Props |
| Jovan Uhrin | Carpenter |
| Noa Tahita Sbragi | Property Buyer |
| Giovanni Miseri | Property Buyer |
| Marco Cardilli | Art Direction |
| Olga Djurdjevic | Art Direction |
| Tiziana Liberotti | Supervising Art Director |
| Andrea Migliaccio | Art Direction |
| Maria Luigia Battani | Set Decoration |
| Dov Samuel | First Assistant Editor |
| Samuel James Bellamy | Additional Editor |
| Hector Cartagena Jr. | Assistant Editor |
| Alessio David Ciattini | Dailies Manager |
| James Durante | VFX Editor |
| Nick Nassif | Additional Colorist |
| Teresa Razzauti | Casting |
| Cristina Giubbetti | Executive Producer |
| Nuno Martins | Line Producer |
| Matteo Albano | First Assistant Director |
| Barbara Bevacqua | Third Assistant Director |
| Rebecca Creighton | Third Assistant Director |
| Annamarie Dicesare | Assistant Director |
| James Excell | Third Assistant Director |
| Sara Fathi | Assistant Director |
| Alex Gavigan | Second Assistant Director |
| Anna Guerra | Assistant Director |
| Alessandro Labadessa | Assistant Director |
| Francesco Liotti | Third Assistant Director |
| Liam Lock | First Assistant Director |
| Maria Cristina Lucantonio | Assistant Director |
| Dewisinta Nogi | Set Production Assistant |
| Jason Rickwood | Second Second Assistant Director |
| Fiorenza Salvador | Second Assistant Director |
| Alberto Scisco | Third Assistant Director |
| Michael Babcock | Sound Re-Recording Mixer |
| Michael J. Benavente | Supervising Dialogue Editor |
| Michael J. Benavente | ADR Editor |
| Ivan Branisavljevic | Boom Operator |
| Claudio Castorina | Boom Operator |
| Emanuela Cotellessa | Sound Mixer |
| Tommaso Gentile | Boom Operator |
| Shane Hayes | Dialogue Editor |
| Novica Jankov | Production Sound Mixer |
| Caitlin McDaid | ADR Mixer |
| Flavio Moro | Boom Operator |
| Daniel Pagan | Sound Effects Editor |
| Zoran Prodanović | Boom Operator |
| Jamison Rabbe | ADR Mixer |
| Joe Schiff | Dialogue Editor |
| Ric Schnupp | Sound Designer |
| Ric Schnupp | Supervising Sound Editor |
| David Semon | Sound Re-Recording Mixer |
| Jussi Tegelman | Sound Designer |
| Jonathan Wales | Sound Re-Recording Mixer |
| Maurizio Corridori | Special Effects Supervisor |
| Gábor Kiszelly | Special Effects Supervisor |
| Gabriele Cumpact | Special Effects Technician |
| Justin Bates | Compositing Supervisor |
| Marlon Victor Bondoc | VFX Artist |
| James Cooper | Visual Effects Supervisor |
| Magdalena Jurcagova | Visual Effects Coordinator |
| Danny McNair | Visual Effects Producer |
| Dave Sauro | Executive Visual Effects Producer |
| Jason Smeyres | Visual Effects Coordinator |
| Slaviša Ivanović | Stunt Coordinator |
| Daniele Anzalone | Stunts |
| Jelena Bakovic | Stunts |
| Emiliano Barretta | Stunt Driver |
| Emiliano Barretta | Stunt Coordinator |
| Alessandro Borgese | Stunt Coordinator |
| Emanuel Comanducci | Utility Stunts |
| Muzio Fumai | Stunts |
| Lucky Johnson | Stunt Double |
| Roberto Dias McCarthy | Stunts |
| Giuliano Pierini | Utility Stunts |
| Patrizia Baiocchi | Assistant Costume Designer |
| Odeta Cali | Costume Coordinator |
| Agustina Castellani | Costumer |
| Anna Cavaliere | Assistant Costume Designer |
| Vanja Damnjanović | Costumer |
| Clara Diana | Set Costumer |
| Augusto Grassi | Costume Supervisor |
| Mariafrancesca Ricci | Seamstress |
| Amy Wright | Costume Coordinator |
| Timothy Visentin | Script Coordinator |
